| RS762559863 |
MFSD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 7, Neuronal ceroid lipofuscinosis 7 |
| RS762559979 |
ALPK3
|
Health Risk |
Pathogenic |
— |
| RS762559980 |
LIPA
|
Health Risk |
Pathogenic |
Wolman disease, Lysosomal acid lipase deficiency |
| RS762560221 |
MEGF10
|
Health Risk |
Conflicting classifications of pathogenicity |
MEGF10-related myopathy, MEGF10-related myopathy |
| RS762561768 |
COL3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, type 4 |
| RS762561997 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS762562272 |
SLC25A38
|
Health Risk |
Pathogenic |
Sideroblastic anemia 2, Sideroblastic anemia 2 |
| RS762566248 |
BBS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 1 |
| RS762567071 |
LONP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762567430 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS762570079 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS762570903 |
FANCM
|
Health Risk |
Pathogenic |
Hereditary breast ovarian cancer syndrome, Fanconi anemia |
| RS762571376 |
TUBGCP4
|
Health Risk |
Pathogenic |
— |
| RS762571378 |
TOP3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762571776 |
ABCB11
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive familial intrahepatic cholestasis type 2, Benign recurrent intrahepatic cholestasis type 2 |
| RS762572576 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS762573043 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 2, Hereditary cancer-predisposing syndrome |
| RS762573767 |
VWA1
|
Health Risk |
Likely pathogenic |
VWA1-related disorder, Neuromuscular disease |
| RS762575015 |
NKX2-1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762576212 |
DGKE
|
Health Risk |
Pathogenic, low penetrance |
Immunoglobulin-mediated membranoproliferative glomerulonephritis, Atypical hemolytic-uremic syndrome |
| RS762576741 |
GFM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1, Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1 |
| RS762576997 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, RASopathy |
| RS762577093 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Familial restrictive cardiomyopathy |
| RS762577403 |
ZFYVE26
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Hereditary spastic paraplegia 15 |
| RS762578274 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS762578912 |
DYNC2H1
|
Health Risk |
Pathogenic |
Autosomal recessive retinitis pigmentosa, Autosomal recessive retinitis pigmentosa |
| RS762580256 |
TRIP11
|
Health Risk |
Conflicting classifications of pathogenicity |
Achondrogenesis, type IA |
| RS762580458 |
NCDN
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with infantile epileptic spasms, Neurodevelopmental disorder with infantile epileptic spasms |
| RS762580578 |
MVK
|
Health Risk |
Conflicting classifications of pathogenicity |
Porokeratosis 3, disseminated superficial actinic type |
| RS762580714 |
KCNA2
|
Health Risk |
Pathogenic |
— |
| RS762583668 |
SLC2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Encephalopathy due to GLUT1 deficiency, Childhood onset GLUT1 deficiency syndrome 2 |
| RS762583937 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, COL6A2-related disorder |
| RS762583993 |
TPP1
|
Health Risk |
Pathogenic |
— |
| RS762584015 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, COL6A3-related disorder |
| RS762584715 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, PKHD1-related disorder |
| RS762586 |
IDUA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis type 1, Inborn genetic diseases |
| RS762587131 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Coffin-Siris syndrome 1, Inborn genetic diseases |
| RS762588205 |
DUOX2
|
Health Risk |
Pathogenic |
DUOX2-related disorder, DUOX2-related disorder |
| RS762588270 |
ALDH18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cutis laxa, autosomal dominant 3 |
| RS762588952 |
DYNC2H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Asphyxiating thoracic dystrophy 3, DYNC2H1-related disorder |
| RS762589415 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS762590281 |
SMARCAL1
|
Health Risk |
Pathogenic |
Schimke immuno-osseous dysplasia, Schimke immuno-osseous dysplasia |
| RS762590394 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Tibial muscular dystrophy |
| RS762590894 |
AICDA
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyper-IgM syndrome type 2, Hyper-IgM syndrome type 2 |
| RS762591075 |
RECQL4
|
Health Risk |
Pathogenic |
Baller-Gerold syndrome, Baller-Gerold syndrome |
| RS762591130 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS762592218 |
TTN
|
Health Risk |
Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS762593235 |
IDUA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis type 1, Mucopolysaccharidosis type 1 |
| RS762593451 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, Cardiovascular phenotype |
| RS762593908 |
ARSA
|
Health Risk |
Pathogenic |
Metachromatic leukodystrophy, Metachromatic leukodystrophy |
| RS762595592 |
TG
|
Health Risk |
Conflicting classifications of pathogenicity |
Iodotyrosyl coupling defect, Iodotyrosyl coupling defect |
| RS762595829 |
FAT4
|
Health Risk |
Conflicting classifications of pathogenicity |
Van Maldergem syndrome 2, Hennekam lymphangiectasia-lymphedema syndrome 2 |
| RS762596098 |
SLC4A11
|
Health Risk |
Pathogenic |
Corneal dystrophy-perceptive deafness syndrome, Corneal dystrophy-perceptive deafness syndrome |
| RS762596479 |
DNAH11
|
Health Risk |
Likely pathogenic |
— |
| RS762597192 |
ADGRV1
|
Health Risk |
Pathogenic |
— |
| RS762598540 |
ADGRV1
|
Health Risk |
Pathogenic |
— |
| RS762598979 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, 8 conditions |
| RS762600030 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex 5C, with pyloric atresia |
| RS762600525 |
FMO3
|
Health Risk |
Likely pathogenic |
Trimethylaminuria, Trimethylaminuria |
| RS762601855 |
BARD1
|
Health Risk |
Likely pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS762602838 |
AGL
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS762602865 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS762603514 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Connective tissue disorder |
| RS76260483 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS762605718 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, Inborn genetic diseases |
| RS762605919 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, Autoinflammatory syndrome |
| RS762606406 |
CLRN1
|
Health Risk |
Pathogenic |
Usher syndrome type 3A, Retinitis pigmentosa |
| RS762607878 |
WDR81
|
Health Risk |
Pathogenic |
Cerebellar ataxia, intellectual disability |
| RS762608746 |
USH2A
|
Health Risk |
Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS762608997 |
DCAF17
|
Health Risk |
Pathogenic |
Woodhouse-Sakati syndrome, Woodhouse-Sakati syndrome |
| RS762609054 |
ADCY5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762610106 |
ETV6
|
Health Risk |
Conflicting classifications of pathogenicity |
Thrombocytopenia 5, Inborn genetic diseases |
| RS762610288 |
SLC34A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive hypophosphatemic bone disease, Autosomal recessive hypophosphatemic bone disease |
| RS762611736 |
DNAI1
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS762612208 |
TCTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 13, Joubert syndrome 13 |
| RS762612242 |
LARGE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy type B6, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS762612591 |
AP4B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 47, Hereditary spastic paraplegia 47 |
| RS762613036 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH9-related disorder, MYH9-related disorder |
| RS762613490 |
MKKS
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS762613611 |
CLCNKB
|
Health Risk |
Likely pathogenic |
— |
| RS762614253 |
NPHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Finnish congenital nephrotic syndrome, Inborn genetic diseases |
| RS762614315 |
ARSB
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucopolysaccharidosis type 6, Mucopolysaccharidosis type 6 |
| RS762615459 |
ANK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spherocytosis type 1, Spherocytosis |
| RS762615993 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS762616491 |
CPT1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 73, Hereditary spastic paraplegia 73 |
| RS762617660 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762619071 |
ACADVL
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS762619360 |
ALDOA
|
Health Risk |
Pathogenic |
HNSHA due to aldolase A deficiency, HNSHA due to aldolase A deficiency |
| RS762619509 |
HSD17B3
|
Health Risk |
Conflicting classifications of pathogenicity |
Testosterone 17-beta-dehydrogenase deficiency, Testosterone 17-beta-dehydrogenase deficiency |
| RS762620949 |
NDUFAF6
|
Health Risk |
Likely pathogenic |
Leigh syndrome, Leigh syndrome |
| RS762621113 |
IDUA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis type 1, Mucopolysaccharidosis type 1 |
| RS762621627 |
BLM
|
Health Risk |
Conflicting classifications of pathogenicity |
Bloom syndrome, Hereditary cancer-predisposing syndrome |
| RS762622002 |
ERCC2
|
Health Risk |
Likely pathogenic |
Cerebrooculofacioskeletal syndrome 2, Cerebrooculofacioskeletal syndrome 2 |
| RS762623799 |
SMARCE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial meningioma, Hereditary cancer-predisposing syndrome |
| RS762624092 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS762624758 |
GARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS762625409 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, COL6A1-related disorder |
| RS762625437 |
RAD51D
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS762626209 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS762626359 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial colorectal cancer, Facial dysmorphism-immunodeficiency-livedo-short stature syndrome |