| RS760423996 |
ACADSB
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of 2-methylbutyryl-CoA dehydrogenase, Clear cell carcinoma of kidney |
| RS760424025 |
STUB1
|
Health Risk |
Likely pathogenic |
Autosomal recessive spinocerebellar ataxia 16, Spinocerebellar ataxia 48 |
| RS760424301 |
ADAMTS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, dermatosparaxis type |
| RS760425899 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS760426025 |
TMEM231
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel syndrome, type 11 |
| RS760426665 |
RGR
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS760426736 |
AFF4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cognitive impairment - coarse facies - heart defects - obesity - pulmonary involvement - short stature - skeletal dysplasia syndrome, AFF4-related disorder |
| RS760426769 |
PKHD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS760428119 |
ALOX12B
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive congenital ichthyosis 2, Autosomal recessive congenital ichthyosis 2 |
| RS760428308 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Episodic ataxia type 2 |
| RS760428437 |
DHCR7
|
Health Risk |
Pathogenic/Likely pathogenic |
Smith-Lemli-Opitz syndrome, Smith-Lemli-Opitz syndrome |
| RS760429286 |
TGM1
|
Health Risk |
Pathogenic |
Autosomal recessive congenital ichthyosis 1, Lamellar ichthyosis |
| RS760429732 |
KBTBD13
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 6, Inborn genetic diseases |
| RS760430056 |
CNGB1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinitis pigmentosa |
| RS760431541 |
SPEN
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, Inborn genetic diseases |
| RS760432217 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 9, Cardiovascular phenotype |
| RS760433367 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal acantholytic epidermolysis bullosa, Arrhythmogenic right ventricular dysplasia 8 |
| RS760433806 |
AMPD2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pontocerebellar hypoplasia type 9, Pontoneocerebellar hypoplasia |
| RS760434412 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS760436036 |
LDLR
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypercholesterolemia, familial |
| RS760437173 |
ZEB2
|
Health Risk |
Pathogenic |
Mowat-Wilson syndrome, Mowat-Wilson syndrome |
| RS760438511 |
SLC25A22
|
Health Risk |
Conflicting classifications of pathogenicity |
Early myoclonic encephalopathy, Early-infantile DEE |
| RS760440073 |
NPHP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Nephronophthisis |
| RS760440581 |
ABCA12
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital ichthyosis of skin, Congenital ichthyosis of skin |
| RS760440966 |
NPHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital nephrotic syndrome, Finnish congenital nephrotic syndrome |
| RS760441649 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS760442721 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS760443264 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2B, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS760445518 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 7, Primary ciliary dyskinesia |
| RS760445854 |
MYH14
|
Health Risk |
Conflicting classifications of pathogenicity |
Peripheral neuropathy-myopathy-hoarseness-hearing loss syndrome, Peripheral neuropathy-myopathy-hoarseness-hearing loss syndrome |
| RS760446904 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Ullrich congenital muscular dystrophy 1A |
| RS760447338 |
TRIP4
|
Health Risk |
Likely pathogenic |
— |
| RS760448302 |
RAG1
|
Health Risk |
Pathogenic |
Combined immunodeficiency with skin granulomas, Severe combined immunodeficiency |
| RS760448993 |
HNF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
HNF1B-related disorder, Type 2 diabetes mellitus |
| RS760451045 |
CUL7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760451348 |
MYORG
|
Health Risk |
Pathogenic |
Basal ganglia calcification, idiopathic |
| RS760451762 |
LAMB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis, LAMB2-related disorder |
| RS760452079 |
RPIA
|
Health Risk |
Pathogenic |
Deficiency of ribose-5-phosphate isomerase, Inborn genetic diseases |
| RS760452532 |
SLC7A9
|
Health Risk |
Pathogenic |
Cystinuria, Cystinuria |
| RS760452661 |
HPS6
|
Health Risk |
Pathogenic |
Hermansky-Pudlak syndrome 6, Hermansky-Pudlak syndrome 6 |
| RS760452917 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS760453324 |
P4HTM
|
Health Risk |
Pathogenic |
— |
| RS760454261 |
DOCK6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760454961 |
PDHX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760455133 |
TMEM231
|
Health Risk |
Pathogenic |
Joubert syndrome 20, Meckel syndrome |
| RS760455624 |
ICOSLG
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760455927 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 39, Retinitis pigmentosa 39 |
| RS760457821 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS760458744 |
MC1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Melanoma, cutaneous malignant |
| RS760459672 |
EVC2
|
Health Risk |
Pathogenic |
Curry-Hall syndrome, Ellis-van Creveld syndrome |
| RS760459724 |
SLC12A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 34 |
| RS760460054 |
COL7A1
|
Health Risk |
Pathogenic |
Transient bullous dermolysis of the newborn, Recessive dystrophic epidermolysis bullosa |
| RS760461056 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 9, Cardiomyopathy |
| RS760461822 |
ALDH5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS760461823 |
MYO15A
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS760462179 |
CUL7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760462252 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Alport syndrome, Autosomal dominant Alport syndrome |
| RS760462654 |
COL4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Brain small vessel disease 1 with or without ocular anomalies |
| RS760466007 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS760467197 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760470297 |
JAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alagille syndrome due to a JAG1 point mutation, Cardiovascular phenotype |
| RS760470520 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS760471578 |
WHRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 31, Usher syndrome type 2D |
| RS760471706 |
PYGM
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type V |
| RS760472019 |
NOTCH3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760472969 |
C8B
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760473402 |
SCLT1
|
Health Risk |
Pathogenic |
— |
| RS760474458 |
TBC1D24
|
Health Risk |
Pathogenic/Likely pathogenic |
DOORS syndrome, Developmental and epileptic encephalopathy |
| RS760476125 |
COL27A1
|
Health Risk |
Likely pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS760477475 |
IMPG2
|
Health Risk |
Pathogenic |
— |
| RS760477654 |
LINS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal recessive 27 |
| RS760478436 |
RP1L1
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa 88, Retinitis pigmentosa 88 |
| RS760479588 |
LDLR
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypercholesterolemia, Hypercholesterolemia |
| RS760479868 |
WDFY3
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 18, primary |
| RS760480600 |
FDXR
|
Health Risk |
Likely pathogenic |
— |
| RS760481450 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS760481743 |
MYH14
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760482209 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS760482527 |
PLA2G6
|
Health Risk |
Conflicting classifications of pathogenicity |
Infantile neuroaxonal dystrophy, Infantile neuroaxonal dystrophy |
| RS760482912 |
COL3A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Ehlers-Danlos syndrome |
| RS760482922 |
LDB3
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Myofibrillar myopathy 4 |
| RS760483684 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS760484081 |
ZFYVE26
|
Health Risk |
Pathogenic |
Spastic paraplegia, Spastic paraplegia |
| RS760484787 |
CEP78
|
Health Risk |
Pathogenic |
Cone-rod dystrophy and hearing loss 1, Cone-rod dystrophy and hearing loss 1 |
| RS760485028 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 1, Hereditary cancer-predisposing syndrome |
| RS760485585 |
BCHE
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of butyrylcholinesterase, Deficiency of butyrylcholinesterase |
| RS76048624 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS760486899 |
ADNP
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760487161 |
LAMA3
|
Health Risk |
Pathogenic/Likely pathogenic |
Junctional epidermolysis bullosa, Epidermolysis bullosa |
| RS760487688 |
TTN
|
Health Risk |
Likely pathogenic |
6 conditions, Cardiovascular phenotype |
| RS76048775 |
IMPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinal dystrophy |
| RS760487849 |
HK1
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with visual defects and brain anomalies, Neurodevelopmental disorder with visual defects and brain anomalies |
| RS760488689 |
BAAT
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760488958 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Charcot-Marie-Tooth disease dominant intermediate E |
| RS760489144 |
IL36RN
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized pustular psoriasis, Autoinflammatory syndrome |
| RS760489473 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS760489717 |
ADCY7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760489970 |
GJB2
|
Health Risk |
Likely pathogenic |
nonsyndromic sensorineural hearing loss, Autosomal recessive nonsyndromic hearing loss 1A |
| RS760490431 |
PAX6
|
Health Risk |
Pathogenic |
Aniridia 1, Aniridia 1 |
| RS760490445 |
MYO15A
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |