| RS760552036 |
LRP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cenani-Lenz syndactyly syndrome, Congenital myasthenic syndrome 17 |
| RS76055256 |
CEP135
|
Health Risk |
Pathogenic |
— |
| RS760552749 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS760552878 |
SPTAN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS760552939 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS760555508 |
TGFBR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Loeys-Dietz syndrome |
| RS760555702 |
SMYD4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760555834 |
DYRK1A
|
Health Risk |
Conflicting classifications of pathogenicity |
DYRK1A-related intellectual disability syndrome, DYRK1A-related intellectual disability syndrome |
| RS760556127 |
RNF43
|
Health Risk |
Conflicting classifications of pathogenicity |
Sessile serrated polyposis cancer syndrome, Sessile serrated polyposis cancer syndrome |
| RS760556162 |
FLCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Birt-Hogg-Dube syndrome |
| RS760556327 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS760557332 |
PDZD7
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760558287 |
MSH6
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS760558712 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypercholesterolemia, Hypercholesterolemia |
| RS760558831 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Recessive dystrophic epidermolysis bullosa, Recessive dystrophic epidermolysis bullosa |
| RS76055909 |
CFAP44
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760559263 |
ZFYVE26
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 15, Spastic paraplegia |
| RS760559303 |
ASL
|
Health Risk |
Likely pathogenic |
Argininosuccinate lyase deficiency, Argininosuccinate lyase deficiency |
| RS760559435 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS760559534 |
BCS1L
|
Health Risk |
Pathogenic |
GRACILE syndrome, Pili torti-deafness syndrome |
| RS760560618 |
RMND1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Combined oxidative phosphorylation defect type 11 |
| RS760561462 |
COL4A3
|
Health Risk |
Pathogenic |
— |
| RS760562117 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS760562478 |
GLDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycine encephalopathy, Glycine encephalopathy |
| RS760562518 |
TFRC
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760564848 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, Inborn genetic diseases |
| RS760565311 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |
| RS760565441 |
CHRNE
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome, CHRNE-related disorder |
| RS760565615 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS760566516 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS760568557 |
HCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS760569139 |
PFKM
|
Health Risk |
Likely pathogenic |
Glycogen storage disease, type VII |
| RS760569328 |
PHKB
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease IXb, Mitochondrial disease |
| RS760569762 |
SMCHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Facioscapulohumeral muscular dystrophy 2, Facioscapulohumeral muscular dystrophy 2 |
| RS760569998 |
LIAS
|
Health Risk |
Pathogenic |
Lipoic acid synthetase deficiency, Lipoic acid synthetase deficiency |
| RS760571406 |
SMAD6
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic valve disease 2, Aortic valve disease 2 |
| RS760571465 |
SERPINH1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760573469 |
PNPLA6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 39, Inborn genetic diseases |
| RS760573914 |
OTOA
|
Health Risk |
Pathogenic/Likely pathogenic |
OTOA-related disorder, Sarcoma |
| RS760574657 |
TECTA
|
Health Risk |
Pathogenic/Likely pathogenic |
Rare genetic deafness, Rare genetic deafness |
| RS760575386 |
C2CD3
|
Health Risk |
Pathogenic |
— |
| RS760575768 |
FIG4
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 4, Inborn genetic diseases |
| RS760576804 |
PKP2
|
Health Risk |
Pathogenic |
Arrhythmogenic right ventricular dysplasia 9, Cardiomyopathy |
| RS760577035 |
HPS3
|
Health Risk |
Pathogenic |
Hermansky-Pudlak syndrome 3, Hermansky-Pudlak syndrome |
| RS760577812 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS760578346 |
C1QTNF5
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS760579409 |
TXNDC15
|
Health Risk |
Pathogenic |
Meckel syndrome 14, Meckel syndrome 14 |
| RS760580647 |
DOCK7
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 23 |
| RS760580885 |
CASP10
|
Health Risk |
Conflicting classifications of pathogenicity |
Autoimmune lymphoproliferative syndrome type 1, Autoimmune lymphoproliferative syndrome type 2A |
| RS760581700 |
PRPF31
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760584131 |
KCNH2
|
Health Risk |
Pathogenic |
Long QT syndrome 2, Long QT syndrome 2 |
| RS760584464 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS760584527 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS760584840 |
PLOD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, kyphoscoliotic type 1 |
| RS760584946 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS760585193 |
PHKA2
|
Health Risk |
Pathogenic |
Glycogen storage disease IXa1, Glycogen storage disease IXa1 |
| RS760586271 |
PKHD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS760587319 |
PSTPIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyogenic arthritis-pyoderma gangrenosum-acne syndrome, Pyogenic arthritis-pyoderma gangrenosum-acne syndrome |
| RS760588490 |
ITPR1
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS760588785 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS760589837 |
AGL
|
Health Risk |
Pathogenic |
Glycogen storage disease type III, Glycogen storage disease type III |
| RS760591174 |
CDC73
|
Health Risk |
Pathogenic |
Parathyroid gland adenoma, Parathyroid carcinoma |
| RS760591932 |
TBC1D24
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Developmental and epileptic encephalopathy |
| RS760592410 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant polycystic kidney disease, Polycystic kidney disease |
| RS760594164 |
TREX1
|
Health Risk |
Pathogenic/Likely pathogenic |
Aicardi-Goutieres syndrome 1, Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations |
| RS760594879 |
UFSP2
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy 106, Developmental and epileptic encephalopathy 106 |
| RS760595439 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS760595654 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS760596943 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS760597183 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS760597240 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS760597333 |
CAPNS1
|
Health Risk |
Pathogenic |
Pulmonary hypertension, primary |
| RS760597864 |
FRMPD4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS760598490 |
ATAD3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual disability |
| RS760598925 |
TMEM43
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS76060070 |
MLYCD
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of malonyl-CoA decarboxylase, Deficiency of malonyl-CoA decarboxylase |
| RS760601613 |
KDM6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome 2, Kabuki syndrome 2 |
| RS760602053 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS760603184 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS760603443 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS760605470 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
CREBBP-related disorder, Rubinstein-Taybi syndrome |
| RS760607210 |
EVC
|
Health Risk |
Pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS760607228 |
UPB1
|
Health Risk |
Pathogenic |
— |
| RS760608076 |
ITPR1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS760608593 |
CDHR1
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS760608643 |
SGCA
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2D, Autosomal recessive limb-girdle muscular dystrophy |
| RS760609383 |
CBS
|
Health Risk |
Likely pathogenic |
Classic homocystinuria, HYPERHOMOCYSTEINEMIA |
| RS760609580 |
CFAP43
|
Health Risk |
Pathogenic |
Spermatogenic failure 19, Spermatogenic failure 19 |
| RS760609798 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS760609808 |
SEMA4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS760609867 |
PLPBP
|
Health Risk |
Pathogenic/Likely pathogenic |
Epilepsy, early-onset |
| RS760611511 |
ABCC6
|
Health Risk |
Likely pathogenic |
— |
| RS760612112 |
F11
|
Health Risk |
Likely pathogenic |
Hereditary factor XI deficiency disease, Hereditary factor XI deficiency disease |
| RS760612966 |
BTD
|
Health Risk |
Likely pathogenic |
Biotinidase deficiency, Biotinidase deficiency |
| RS760613522 |
GRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 3, Fraser syndrome 3 |
| RS760613992 |
BSCL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Congenital generalized lipodystrophy type 2 |
| RS76061451 |
CNGA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa 49 |
| RS760614599 |
TGIF2LY
|
Health Risk |
Likely pathogenic |
Male infertility with azoospermia or oligozoospermia due to single gene mutation, Male infertility with azoospermia or oligozoospermia due to single gene mutation |
| RS760615315 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS760615496 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory and autonomic |