| RS752493616 |
NLRP12
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cold autoinflammatory syndrome 2, NLRP12-related disorder |
| RS752494819 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
DDX41-related hematologic malignancy predisposition syndrome, Inborn genetic diseases |
| RS752495145 |
DNMT3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency-centromeric instability-facial anomalies syndrome 1, Centromeric instability of chromosomes 1 |
| RS752495590 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Inborn genetic diseases |
| RS752496736 |
PKD1L1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752497243 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752497984 |
POMGNT1
|
Health Risk |
Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A3 |
| RS752499497 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS752500112 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Spinocerebellar ataxia |
| RS752500492 |
POLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive sclerosing poliodystrophy, Hereditary spastic paraplegia |
| RS752500721 |
BRD4
|
Health Risk |
Likely pathogenic |
Mental disorder, Mental disorder |
| RS752501149 |
TEX15
|
Health Risk |
Likely pathogenic |
Spermatogenic failure 25, Spermatogenic failure 25 |
| RS752501243 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS752501574 |
SLC45A2
|
Health Risk |
Pathogenic |
SKIN/HAIR/EYE PIGMENTATION 5, BLACK/NONBLACK HAIR |
| RS752502287 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS752503322 |
FOLR1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cerebral folate transport deficiency, Cerebral folate transport deficiency |
| RS752503425 |
XRCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS752504125 |
FOXF1
|
Health Risk |
Likely pathogenic |
VATER association, VATER association |
| RS752504462 |
EYS
|
Health Risk |
Pathogenic |
Retinitis pigmentosa 25, Retinitis pigmentosa 25 |
| RS752505638 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Familial thoracic aortic aneurysm and aortic dissection |
| RS752505720 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752506584 |
PEX10
|
Health Risk |
Likely pathogenic |
Peroxisome biogenesis disorder 6A (Zellweger), Peroxisome biogenesis disorder 6A (Zellweger) |
| RS752506719 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1DD, Cardiovascular phenotype |
| RS752506833 |
DAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2P, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS752507559 |
LAS1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson-Turner syndrome, Wilson-Turner syndrome |
| RS752508274 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Kleefstra syndrome 1 |
| RS752509045 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, PKHD1-related disorder |
| RS752509098 |
ALOX12B
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive congenital ichthyosis 2, Lamellar ichthyosis |
| RS752509706 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
COL4A4-related disorder, Hematuria |
| RS752509887 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752510156 |
MYH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Freeman-Sheldon syndrome, Distal arthrogryposis type 2B1 |
| RS752510317 |
ERCC2
|
Health Risk |
Pathogenic/Likely pathogenic |
Cerebrooculofacioskeletal syndrome 2, Trichothiodystrophy 1 |
| RS752510351 |
OCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
OCA2-related disorder, Tyrosinase-positive oculocutaneous albinism |
| RS752510907 |
DIAPH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 1, Progressive microcephaly-seizures-cortical blindness-developmental delay syndrome |
| RS752511532 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS752513328 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypokalemic periodic paralysis, type 1 |
| RS752513330 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS752513342 |
CEP290
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Meckel-Gruber syndrome |
| RS752513498 |
PALB2
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS752513525 |
NDUFA13
|
Health Risk |
Likely pathogenic |
Mitochondrial complex I deficiency, nuclear type 28 |
| RS752513542 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS752514155 |
BARD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS752514306 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS752514808 |
KCNT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal dominant nocturnal frontal lobe epilepsy 5, Developmental and epileptic encephalopathy |
| RS752515390 |
PTPN23
|
Health Risk |
Pathogenic |
— |
| RS752516170 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, Developmental and epileptic encephalopathy |
| RS752518735 |
CEP164
|
Health Risk |
Pathogenic |
Nephronophthisis 15, Nephronophthisis 15 |
| RS752518966 |
DES
|
Health Risk |
Conflicting classifications of pathogenicity |
Desmin-related myofibrillar myopathy, Cardiovascular phenotype |
| RS752519066 |
APC
|
Health Risk |
Pathogenic |
Familial adenomatous polyposis 1, Familial adenomatous polyposis 1 |
| RS752519227 |
AP3B1
|
Health Risk |
Pathogenic |
Hermansky-Pudlak syndrome 2, Hermansky-Pudlak syndrome 2 |
| RS752519410 |
IL10RA
|
Health Risk |
Conflicting classifications of pathogenicity |
Inflammatory bowel disease 28, Inflammatory bowel disease 28 |
| RS752521456 |
BEST1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive bestrophinopathy, Retinal dystrophy |
| RS752521629 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Becker muscular dystrophy |
| RS752522727 |
ALPK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752522753 |
DSG2
|
Health Risk |
Pathogenic/Likely pathogenic |
Arrhythmogenic right ventricular dysplasia 10, Cardiovascular phenotype |
| RS752523070 |
ALDH7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyridoxine-dependent epilepsy, Inborn genetic diseases |
| RS752523300 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Choanal atresia-athelia-hypothyroidism-delayed puberty-short stature syndrome, Kabuki syndrome 1 |
| RS752523400 |
GUSB
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis type 7, Inborn genetic diseases |
| RS752523459 |
SCN4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Paramyotonia congenita of Von Eulenburg, Hyperkalemic periodic paralysis |
| RS752523704 |
CIB2
|
Health Risk |
Pathogenic |
— |
| RS752523757 |
MTMR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752525400 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, Cardiovascular phenotype |
| RS752526400 |
ATM
|
Health Risk |
Pathogenic |
Ataxia-telangiectasia syndrome, Familial cancer of breast |
| RS752526782 |
MTR
|
Health Risk |
Pathogenic |
Methylcobalamin deficiency type cblG, Methylcobalamin deficiency type cblG |
| RS752527478 |
NAGLU
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-B |
| RS752527657 |
CCNO
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 29, Primary ciliary dyskinesia 29 |
| RS752528409 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease type 4C |
| RS752528416 |
ABCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypoalphalipoproteinemia, primary |
| RS752528550 |
IFT43
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752530061 |
VPS13A
|
Health Risk |
Pathogenic |
— |
| RS752530417 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS752530755 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS752531051 |
PNPLA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neutral lipid storage myopathy, Neutral lipid storage myopathy |
| RS752531162 |
ATP6V0A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive distal renal tubular acidosis, Autosomal recessive distal renal tubular acidosis |
| RS752531267 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, KMT2D-related disorder |
| RS752532048 |
HID1
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS752532336 |
DNAAF19
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 17, Primary ciliary dyskinesia |
| RS752532497 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS752532578 |
MSH6
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS752532780 |
SDHA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex II deficiency, nuclear type 1 |
| RS752534420 |
PHIP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752534913 |
ANO5
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2L, Gnathodiaphyseal dysplasia |
| RS752534981 |
ACSF3
|
Health Risk |
Likely pathogenic |
Combined malonic and methylmalonic acidemia, Combined malonic and methylmalonic acidemia |
| RS752535248 |
FOXC1
|
Health Risk |
Pathogenic |
— |
| RS752535474 |
MBD5
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability, autosomal dominant 1 |
| RS752535640 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Renal cell carcinoma |
| RS752536081 |
MYLK
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 7 |
| RS752536342 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
BAP1-related tumor predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS752537118 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial adenomatous polyposis 2, Carcinoma of colon |
| RS752537557 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752537599 |
SYT2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752537626 |
GALC
|
Health Risk |
Pathogenic/Likely pathogenic |
Galactosylceramide beta-galactosidase deficiency, Inborn genetic diseases |
| RS752538741 |
RET
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 2 |
| RS752539001 |
TNFAIP3
|
Health Risk |
Likely pathogenic |
Autoinflammatory syndrome, familial |
| RS752539924 |
IFT74
|
Health Risk |
Pathogenic |
— |
| RS752540777 |
CYP17A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of steroid 17-alpha-monooxygenase, Deficiency of steroid 17-alpha-monooxygenase |
| RS752540976 |
MSH6
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Lynch syndrome 5 |
| RS752541064 |
MAN2B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS752541243 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Neurofibromatosis |
| RS752542644 |
WRN
|
Health Risk |
Conflicting classifications of pathogenicity |
Werner syndrome, Werner syndrome |