| RS752428321 |
MLC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Megalencephalic leukoencephalopathy with subcortical cysts 1, Megalencephalic leukoencephalopathy with subcortical cysts |
| RS752428475 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS752428699 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Adams-Oliver syndrome 5 |
| RS752429062 |
VPS13B
|
Health Risk |
Pathogenic/Likely pathogenic |
Cohen syndrome, Cohen syndrome |
| RS752429712 |
PDE6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital stationary night blindness autosomal dominant 2, Retinitis pigmentosa |
| RS752429719 |
BNC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752429735 |
BBS7
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome 7, Bardet-Biedl syndrome 7 |
| RS752430880 |
PIK3R2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Megalencephaly-polymicrogyria-postaxial polydactyly-hydrocephalus syndrome |
| RS752431578 |
COL1A2
|
Health Risk |
Pathogenic |
Ehlers-Danlos syndrome, classic type |
| RS752431673 |
ENG
|
Health Risk |
Conflicting classifications of pathogenicity |
Telangiectasia, hereditary hemorrhagic |
| RS752432041 |
AIRE
|
Health Risk |
Conflicting classifications of pathogenicity |
Polyglandular autoimmune syndrome, type 1 |
| RS752432156 |
PRKAR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Carney complex, type 1 |
| RS752432261 |
SCNN1G
|
Health Risk |
Conflicting classifications of pathogenicity |
Liddle syndrome 2, Pseudohypoaldosteronism |
| RS752432317 |
SON
|
Health Risk |
Conflicting classifications of pathogenicity |
ZTTK syndrome, ZTTK syndrome |
| RS752433735 |
ADAMTS2
|
Health Risk |
Pathogenic |
Ehlers-Danlos syndrome, dermatosparaxis type |
| RS752434188 |
DNMT3A
|
Health Risk |
Conflicting classifications of pathogenicity |
DNMT3A-related disorder, Inborn genetic diseases |
| RS752434998 |
HESX1
|
Health Risk |
Conflicting classifications of pathogenicity |
GROWTH HORMONE DEFICIENCY WITH PITUITARY ANOMALIES, Septo-optic dysplasia sequence |
| RS752435825 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS752436384 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS752436391 |
RP1L1
|
Health Risk |
Likely pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS752436924 |
CHKB
|
Health Risk |
Pathogenic |
Megaconial type congenital muscular dystrophy, Megaconial type congenital muscular dystrophy |
| RS752437276 |
C9
|
Health Risk |
Pathogenic/Likely pathogenic |
Age related macular degeneration 15, Complement component 9 deficiency |
| RS752439023 |
ADGRG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bilateral frontoparietal polymicrogyria, Bilateral frontoparietal polymicrogyria |
| RS752440109 |
POMT2
|
Health Risk |
Pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B2 |
| RS752440638 |
PEPD
|
Health Risk |
Conflicting classifications of pathogenicity |
Prolidase deficiency, Prolidase deficiency |
| RS752441031 |
DAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A9 |
| RS752441753 |
LARS1
|
Health Risk |
Pathogenic |
Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins, Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins |
| RS752442185 |
SAMHD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Aicardi-Goutieres syndrome 5, Chilblain lupus 2 |
| RS752442261 |
NEB
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS752443408 |
COL4A5
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked Alport syndrome, COL4A5-related disorder |
| RS752443893 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS752444746 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Colorectal cancer |
| RS752447493 |
MPI
|
Health Risk |
Pathogenic |
MPI-congenital disorder of glycosylation, MPI-congenital disorder of glycosylation |
| RS752448040 |
FLNC
|
Health Risk |
Pathogenic |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS752448493 |
DDX11
|
Health Risk |
Likely pathogenic |
Warsaw breakage syndrome, Warsaw breakage syndrome |
| RS752449341 |
DYNC2H1
|
Health Risk |
Likely pathogenic |
Jeune thoracic dystrophy, Jeune thoracic dystrophy |
| RS752450605 |
DCLRE1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Histiocytic medullary reticulosis, Severe combined immunodeficiency due to DCLRE1C deficiency |
| RS752450678 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS752450856 |
HIBCH
|
Health Risk |
Likely pathogenic |
3-hydroxyisobutyryl-CoA hydrolase deficiency, 3-hydroxyisobutyryl-CoA hydrolase deficiency |
| RS752450983 |
C19orf12
|
Health Risk |
Pathogenic/Likely pathogenic |
Global developmental delay, Intellectual disability |
| RS752452129 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS752452590 |
COL4A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive Alport syndrome, Alport syndrome 3b |
| RS752452731 |
PRKRA
|
Health Risk |
Pathogenic/Likely pathogenic |
Dystonia 16, Dystonia 16 |
| RS752452948 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS752453368 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS752453717 |
MPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital amegakaryocytic thrombocytopenia, Essential thrombocythemia |
| RS752453773 |
EPHB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS752455591 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS752457145 |
KCNQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiac arrhythmia, Cardiovascular phenotype |
| RS752457309 |
VPS13C
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive early-onset Parkinson disease 23, Young-onset Parkinson disease |
| RS752457319 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia, Fanconi anemia complementation group A |
| RS752458888 |
CRX
|
Health Risk |
Conflicting classifications of pathogenicity |
Leber congenital amaurosis 7, Cone-rod dystrophy 2 |
| RS752459996 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS752460023 |
OCA2
|
Health Risk |
Pathogenic/Likely pathogenic |
SKIN/HAIR/EYE PIGMENTATION 1, BLUE/NONBLUE EYES |
| RS752460436 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS752461164 |
MYO5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Griscelli syndrome type 1, MYO5A-related disorder |
| RS752461187 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Wolfram syndrome 1, See cases |
| RS752462796 |
SDHAF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary pheochromocytoma and paraganglioma, Ovarian cancer |
| RS752463700 |
TTPA
|
Health Risk |
Pathogenic |
— |
| RS752464745 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS752465293 |
WRN
|
Health Risk |
Likely pathogenic |
Werner syndrome, Werner syndrome |
| RS752465579 |
FANCI
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Inborn genetic diseases |
| RS752466285 |
MACF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS752468216 |
CPT2
|
Health Risk |
Pathogenic/Likely pathogenic |
Carnitine palmitoyltransferase II deficiency, Carnitine palmitoyl transferase II deficiency |
| RS752469036 |
MVK
|
Health Risk |
Conflicting classifications of pathogenicity |
Mevalonic aciduria, Porokeratosis 3 |
| RS752469952 |
WNK4
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Pseudohypoaldosteronism type 2B |
| RS752470665 |
ALDH18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
ALDH18A1-related de Barsy syndrome, de Barsy syndrome |
| RS752472169 |
ARL13B
|
Health Risk |
Pathogenic |
Joubert syndrome 8, Joubert syndrome and related disorders |
| RS752473055 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate B, Inborn genetic diseases |
| RS752473063 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 1, Hereditary cancer-predisposing syndrome |
| RS752473164 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS752473449 |
ABHD5
|
Health Risk |
Pathogenic |
— |
| RS752473648 |
LMF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, LMF1-related disorder |
| RS752474843 |
BRCA1
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS752476527 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Sick sinus syndrome 1, Long QT syndrome 3 |
| RS752476855 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |
| RS752477271 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Congenital multicore myopathy with external ophthalmoplegia |
| RS752477890 |
MAX
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary pheochromocytoma and paraganglioma |
| RS752477959 |
KMT2D
|
Health Risk |
Conflicting classifications of pathogenicity |
Kabuki syndrome, Kabuki syndrome 1 |
| RS752478345 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia-telangiectasia syndrome, Hereditary cancer-predisposing syndrome |
| RS752478645 |
PDE6C
|
Health Risk |
Conflicting classifications of pathogenicity |
Achromatopsia, Cone dystrophy 4 |
| RS752478913 |
MAN1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Rafiq syndrome, Rafiq syndrome |
| RS752479330 |
SPAG1
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia 28, Primary ciliary dyskinesia 28 |
| RS752479889 |
DYSF
|
Health Risk |
Pathogenic |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Neuromuscular disease caused by qualitative or quantitative defects of dysferlin |
| RS752480853 |
FUCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Fucosidosis |
| RS752482499 |
SLC7A8
|
Health Risk |
Likely pathogenic |
Short stature, Short stature |
| RS752484607 |
RAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS752485540 |
SLC26A4
|
Health Risk |
Pathogenic |
— |
| RS752485547 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy, limb-girdle |
| RS752485728 |
HADHB
|
Health Risk |
Likely pathogenic |
Mitochondrial trifunctional protein deficiency, Mitochondrial trifunctional protein deficiency |
| RS752487562 |
CHRNG
|
Health Risk |
Pathogenic |
— |
| RS752487771 |
ATP13A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive spastic paraplegia type 78, Kufor-Rakeb syndrome |
| RS752488141 |
DNAAF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 10 |
| RS752488156 |
TPM4
|
Health Risk |
Pathogenic |
Bleeding disorder, platelet-type |
| RS752489470 |
LZTR1
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Cardiovascular phenotype |
| RS752492512 |
RASGRP2
|
Health Risk |
Pathogenic/Likely pathogenic |
Abnormal platelet aggregation, Platelet-type bleeding disorder 18 |
| RS752492830 |
WNK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudohypoaldosteronism type 2C, Neuropathy |
| RS752492870 |
SGCB
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2E, Limb-girdle muscular dystrophy |
| RS752493018 |
KLHL40
|
Health Risk |
Likely pathogenic |
Nemaline myopathy 8, Nemaline myopathy 8 |
| RS752493285 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |