| RS571733505 |
SPTB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571739078 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS571740084 |
SLC4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive distal renal tubular acidosis, Renal tubular acidosis |
| RS571742202 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS571742271 |
LEMD3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS571757257 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS571767462 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS571769859 |
DOK7
|
Health Risk |
Likely pathogenic |
Fetal akinesia deformation sequence 1, Congenital myasthenic syndrome 10 |
| RS571792728 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Isolated focal cortical dysplasia type II, Hereditary cancer-predisposing syndrome |
| RS571797590 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex, Ogna type |
| RS57179857 |
ABCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCC6-related disorder, ABCC6-related disorder |
| RS571799365 |
MPDZ
|
Health Risk |
Pathogenic |
Hydrocephalus, nonsyndromic |
| RS571800639 |
PIEZO2
|
Health Risk |
Pathogenic |
— |
| RS571800995 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS571806809 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS571809727 |
EVC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS571810545 |
TYR
|
Health Risk |
Pathogenic/Likely pathogenic |
SKIN/HAIR/EYE PIGMENTATION 3, LIGHT/DARK SKIN |
| RS571812048 |
SPINK5
|
Health Risk |
Conflicting classifications of pathogenicity |
Netherton syndrome, Ichthyosis linearis circumflexa |
| RS571817807 |
ATP6V1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571823764 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS571824470 |
PLOD1
|
Health Risk |
Likely pathogenic |
Ehlers-Danlos syndrome, kyphoscoliotic type 1 |
| RS571831870 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic valve disease 1, Adams-Oliver syndrome 5 |
| RS571832030 |
MEFV
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial Mediterranean fever, Inborn genetic diseases |
| RS571832933 |
TPO
|
Health Risk |
Likely pathogenic |
— |
| RS571833399 |
IDUA
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Mucopolysaccharidosis type 1 |
| RS571837788 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571850239 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital multicore myopathy with external ophthalmoplegia, Malignant hyperthermia |
| RS571854709 |
PLEKHG2
|
Health Risk |
Conflicting classifications of pathogenicity |
PLEKHG2-related disorder, PLEKHG2-related disorder |
| RS571858561 |
DYNC1H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2O, Charcot-Marie-Tooth disease axonal type 2O |
| RS571861704 |
ITGB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Junctional epidermolysis bullosa with pyloric atresia, Epidermolysis bullosa |
| RS571869797 |
COL4A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive Alport syndrome, Benign familial hematuria |
| RS571871217 |
CLPB
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylglutaconic aciduria, type VIIB |
| RS57187183 |
KRT5
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex 2C, localized |
| RS571875820 |
CPLANE1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS571894941 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex 5C, with pyloric atresia |
| RS571899254 |
KCNQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS571903706 |
HBA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS571906190 |
MYO1A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS571918997 |
PIEZO2
|
Health Risk |
Likely pathogenic |
Arthrogryposis, distal |
| RS571919972 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS571926464 |
ETV6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS57193077 |
ALB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperthyroxinemia, familial dysalbuminemic |
| RS571932580 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS571935637 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS571938170 |
EPM2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive myoclonic epilepsy, Inborn genetic diseases |
| RS571940397 |
CLN6
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis, Neuronal ceroid lipofuscinosis |
| RS571941412 |
PRRT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic kinesigenic dyskinesia, Episodic kinesigenic dyskinesia |
| RS571944290 |
VPS13C
|
Health Risk |
Pathogenic |
— |
| RS571945132 |
GALC
|
Health Risk |
Conflicting classifications of pathogenicity |
Galactosylceramide beta-galactosidase deficiency, Galactosylceramide beta-galactosidase deficiency |
| RS571946670 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS571950296 |
MFSD8
|
Health Risk |
Pathogenic/Likely pathogenic |
Neuronal ceroid lipofuscinosis 7, Late-infantile neuronal ceroid lipofuscinosis |
| RS571950456 |
PKD2
|
Health Risk |
Pathogenic |
— |
| RS571952564 |
ENPP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Type 2 diabetes mellitus, Hypopigmentation-punctate palmoplantar keratoderma syndrome |
| RS571962145 |
XYLT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta, XYLT2-related disorder |
| RS571966529 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, PKHD1-related disorder |
| RS571971903 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS571976990 |
SKI
|
Health Risk |
Conflicting classifications of pathogenicity |
Shprintzen-Goldberg syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS571979064 |
CANT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Desbuquois dysplasia 1, Desbuquois dysplasia 1 |
| RS571981688 |
COL11A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571985775 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Left ventricular noncompaction, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS571986845 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571986941 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate E, Focal segmental glomerulosclerosis 5 |
| RS571997198 |
SIX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 23, Branchiootic syndrome 3 |
| RS571999908 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS572007088 |
COL12A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ullrich congenital muscular dystrophy 2, Bethlem myopathy 2 |
| RS572010193 |
FAT4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS572010627 |
MPZ
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease, type I |
| RS572010910 |
ACADVL
|
Health Risk |
Conflicting classifications of pathogenicity |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS572013653 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS572017658 |
SLC39A13
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, spondylocheirodysplastic type |
| RS572018781 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS572020866 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS572021052 |
PROC
|
Health Risk |
Conflicting classifications of pathogenicity |
Thrombophilia due to protein C deficiency, autosomal dominant |
| RS572021323 |
ADGRG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bilateral frontoparietal polymicrogyria, Bilateral frontoparietal polymicrogyria |
| RS572028093 |
PEX14
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, complementation group K |
| RS572034879 |
CFH
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 4, CFH-Related Dense Deposit Disease / Membranoproliferative Glomerulonephritis Type II |
| RS572036022 |
BAG3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 6, Dilated cardiomyopathy 1HH |
| RS572038196 |
BAG3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 6, Dilated cardiomyopathy 1HH |
| RS572043133 |
ABCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypoalphalipoproteinemia, primary |
| RS572043246 |
KAT8
|
Health Risk |
Conflicting classifications of pathogenicity |
Li-Ghorbani-Weisz-Hubshman syndrome, Li-Ghorbani-Weisz-Hubshman syndrome |
| RS572044496 |
ALDOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary fructosuria, Hereditary fructosuria |
| RS572052810 |
TRIM32
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 11, Sarcotubular myopathy |
| RS572056540 |
EVC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Curry-Hall syndrome, Ellis-van Creveld syndrome |
| RS572061488 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS572063023 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
BAP1-related tumor predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS57207746 |
LMNA
|
Health Risk |
Pathogenic/Likely pathogenic |
Emery-Dreifuss muscular dystrophy 2, autosomal dominant |
| RS572081330 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Susceptibility to mononeuropathy of the median nerve, mild |
| RS572089064 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS572095826 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS572097661 |
COL3A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Ehlers-Danlos syndrome, type 4 |
| RS572101154 |
ABCA3
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS572102702 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS572110753 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Inborn genetic diseases |
| RS572115942 |
PHKG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Mauriac syndrome, Glycogen storage disease IXc |
| RS572116317 |
MYO18B
|
Health Risk |
Likely pathogenic |
Klippel-Feil anomaly-myopathy-facial dysmorphism syndrome, Klippel-Feil anomaly-myopathy-facial dysmorphism syndrome |
| RS572118148 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS572122562 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS572124553 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex 5C, with pyloric atresia |
| RS572126510 |
AFF4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cognitive impairment - coarse facies - heart defects - obesity - pulmonary involvement - short stature - skeletal dysplasia syndrome, Inborn genetic diseases |
| RS572132215 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Distal myopathy with posterior leg and anterior hand involvement |