| RS573119781 |
HMCN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 1, Age related macular degeneration 1 |
| RS573123885 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS573125799 |
PMS2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Lynch syndrome |
| RS573136400 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS57315342 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS573154781 |
CD19
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, common variable |
| RS573157071 |
ABAT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gamma-aminobutyric acid transaminase deficiency, Gamma-aminobutyric acid transaminase deficiency |
| RS573158320 |
SPINK5
|
Health Risk |
Conflicting classifications of pathogenicity |
Ichthyosis linearis circumflexa, Inborn genetic diseases |
| RS573163079 |
PDE11A
|
Health Risk |
Conflicting classifications of pathogenicity |
Pigmented nodular adrenocortical disease, primary |
| RS573164516 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Inborn genetic diseases |
| RS573165930 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS573177564 |
DHODH
|
Health Risk |
Conflicting classifications of pathogenicity |
Miller syndrome, Miller syndrome |
| RS573185206 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS57318642 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mandibuloacral dysplasia with type A lipodystrophy, Hutchinson-Gilford syndrome |
| RS573187346 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS573192954 |
NPHP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Nephronophthisis, Inborn genetic diseases |
| RS573213368 |
SZT2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS573218266 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS573222502 |
POT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumor predisposition syndrome 3, Hereditary cancer-predisposing syndrome |
| RS573246972 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS573255254 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS573258363 |
GSDME
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, GSDME-related disorder |
| RS573267388 |
PMPCA
|
Health Risk |
Pathogenic |
Autosomal recessive spinocerebellar ataxia 2, Autosomal recessive spinocerebellar ataxia 2 |
| RS573270795 |
GUCY2D
|
Health Risk |
Likely pathogenic |
Leber congenital amaurosis 1, Leber congenital amaurosis 1 |
| RS573275770 |
LZTR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Cardiovascular phenotype |
| RS573279159 |
BIVM-ERCC5;ERCC5
|
Health Risk |
Conflicting classifications of pathogenicity |
Ovarian cancer, Ovarian cancer |
| RS573282005 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS573282230 |
GNPTAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucolipidosis type II, Pseudo-Hurler polydystrophy |
| RS573282381 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Familial thoracic aortic aneurysm and aortic dissection |
| RS573290117 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS573290536 |
TTC21B
|
Health Risk |
Conflicting classifications of pathogenicity |
Asphyxiating thoracic dystrophy 4, Nephronophthisis 12 |
| RS573301881 |
SETD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Luscan-Lumish syndrome, Inborn genetic diseases |
| RS573302664 |
HIBCH
|
Health Risk |
Conflicting classifications of pathogenicity |
3-hydroxyisobutyryl-CoA hydrolase deficiency, See cases |
| RS573306680 |
GOSR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive myoclonic epilepsy, Progressive myoclonic epilepsy type 6 |
| RS57330753 |
LOXHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 77, Autosomal recessive nonsyndromic hearing loss 77 |
| RS573308525 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS573313754 |
AGT
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal tubular dysgenesis, AGT-related disorder |
| RS573319891 |
TTLL5
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS573322878 |
FGF23
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumoral calcinosis, hyperphosphatemic |
| RS573327073 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
RAI1-related disorder, Inborn genetic diseases |
| RS573330522 |
COCH
|
Health Risk |
Conflicting classifications of pathogenicity |
COCH-related disorder, COCH-related disorder |
| RS573350587 |
FKBP10
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type 11, Osteogenesis imperfecta |
| RS573353481 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
PIEZO1-related disorder, PIEZO1-related disorder |
| RS573353679 |
CDKN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia type 4, Hereditary cancer-predisposing syndrome |
| RS573362121 |
FLNC
|
Health Risk |
Pathogenic |
Primary familial dilated cardiomyopathy, Primary familial dilated cardiomyopathy |
| RS573374779 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS573384357 |
PHKB
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease IXb, Glycogen storage disease IXb |
| RS573384750 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS573388805 |
FLG
|
Health Risk |
Pathogenic |
— |
| RS573399358 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 5, Hypertrophic cardiomyopathy 26 |
| RS573401319 |
LCT
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital lactase deficiency, Congenital lactase deficiency |
| RS573406234 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS573415766 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS573418899 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
ABCA4-related disorder, ABCA4-related disorder |
| RS573424409 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex with nail dystrophy, Autosomal recessive limb-girdle muscular dystrophy type 2Q |
| RS573426783 |
RBM20
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1DD |
| RS573431795 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS573432153 |
COL7A1
|
Health Risk |
Pathogenic |
7 conditions, 7 conditions |
| RS573432571 |
HNF4A
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hyperinsulinism, Maturity-onset diabetes of the young type 1 |
| RS573432728 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex 5B, with muscular dystrophy |
| RS573433508 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 6, WFS1-Related Spectrum Disorders |
| RS573435546 |
RRM2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 8a, Progressive external ophthalmoplegia with mitochondrial DNA deletions |
| RS573438233 |
SPTB
|
Health Risk |
Likely pathogenic |
— |
| RS573444140 |
SLC12A6
|
Health Risk |
Pathogenic |
Agenesis of the corpus callosum with peripheral neuropathy, Agenesis of the corpus callosum with peripheral neuropathy |
| RS573444416 |
SPTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS57344541 |
AHCY
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase, Hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase |
| RS573447174 |
HEXB
|
Health Risk |
Pathogenic |
Sandhoff disease, Sandhoff disease |
| RS573454071 |
SLC7A7
|
Health Risk |
Conflicting classifications of pathogenicity |
Lysinuric protein intolerance, Lysinuric protein intolerance |
| RS573463511 |
BMPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary pulmonary hypertension, Inborn genetic diseases |
| RS573466361 |
MTOR
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS573472397 |
FBXL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial DNA depletion syndrome 13, FBXL4-related disorder |
| RS573474554 |
TNRC6A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS573476401 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS57348201 |
KRT5
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex 2B, generalized intermediate |
| RS573482671 |
SPG11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 11, Amyotrophic lateral sclerosis type 5 |
| RS573483617 |
CTSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 13, Inborn genetic diseases |
| RS573484984 |
IL21R
|
Health Risk |
Conflicting classifications of pathogenicity |
Cryptosporidiosis-chronic cholangitis-liver disease syndrome, Inborn genetic diseases |
| RS573487375 |
DUOX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS573493017 |
PRPF8
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS573498430 |
GCKR
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS573499594 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Amyotrophic lateral sclerosis type 4 |
| RS573508258 |
UNC13D
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemophagocytic lymphohistiocytosis 3, Autoinflammatory syndrome |
| RS573509767 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS573510559 |
LBR
|
Health Risk |
Pathogenic/Likely pathogenic |
Regressive spondylometaphyseal dysplasia, Pelger-Huët anomaly |
| RS573511043 |
FAT2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS573514896 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS573518562 |
POMGNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Autosomal recessive limb-girdle muscular dystrophy type 2O |
| RS573523090 |
CIITA
|
Health Risk |
Likely pathogenic |
MHC class II deficiency 1, MHC class II deficiency 1 |
| RS573525939 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS573527081 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Alport syndrome, Nephrotic syndrome |
| RS573528468 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS573530168 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa dystrophica, Epidermolysis bullosa dystrophica |
| RS573535377 |
ATP1A3
|
Health Risk |
Pathogenic |
Dystonia 12, Dystonia 12 |
| RS573545872 |
DDX41
|
Health Risk |
Conflicting classifications of pathogenicity |
DDX41-related hematologic malignancy predisposition syndrome, DDX41-related disorder |
| RS573554562 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Hypogonadotropic hypogonadism 5 with or without anosmia |
| RS573566419 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Polycystic kidney disease, adult type |
| RS573567814 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis 5, Charcot-Marie-Tooth disease dominant intermediate E |
| RS573577299 |
P3H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type 8, Inborn genetic diseases |
| RS573582812 |
RGPD8
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS573586512 |
MYO15A
|
Health Risk |
Likely pathogenic |
— |