| RS571306161 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
WFS1-related disorder, WFS1-related disorder |
| RS571307356 |
MYO6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 37, Autosomal dominant nonsyndromic hearing loss 22 |
| RS571326568 |
RHOBTB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571328201 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS571329853 |
SHQ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dystonia 35, childhood-onset |
| RS571342427 |
INS
|
Health Risk |
Conflicting classifications of pathogenicity |
Type 2 diabetes mellitus, INS-related disorder |
| RS571347913 |
GAN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571348685 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS571348995 |
ELP1
|
Health Risk |
Likely pathogenic |
Familial dysautonomia, Medulloblastoma |
| RS571353547 |
MATN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Connective tissue disorder |
| RS571357479 |
FLAD1
|
Health Risk |
Conflicting classifications of pathogenicity |
FLAD1-related disorder, Myopathy with abnormal lipid metabolism |
| RS571363127 |
DICER1
|
Health Risk |
Conflicting classifications of pathogenicity |
DICER1-related tumor predisposition, DICER1-related tumor predisposition |
| RS571364996 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Miyoshi muscular dystrophy 1 |
| RS571365493 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS571375136 |
JUP
|
Health Risk |
Conflicting classifications of pathogenicity |
Naxos disease, Arrhythmogenic right ventricular dysplasia 12 |
| RS571376371 |
SLC4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant distal renal tubular acidosis, Renal tubular acidosis |
| RS571389435 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Cardiovascular phenotype |
| RS571392819 |
SMARCAL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schimke immuno-osseous dysplasia, SMARCAL1-related disorder |
| RS571402316 |
JAK3
|
Health Risk |
Conflicting classifications of pathogenicity |
T-B+ severe combined immunodeficiency due to JAK3 deficiency, JAK3-related disorder |
| RS571408451 |
SOS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Fibromatosis, gingival |
| RS571409000 |
KARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS571417296 |
TMPO
|
Health Risk |
Conflicting classifications of pathogenicity |
Loeys-Dietz syndrome 2, Loeys-Dietz syndrome 2 |
| RS571419754 |
CNGA3
|
Health Risk |
Likely pathogenic |
Achromatopsia 2, Achromatopsia 2 |
| RS57142010 |
KRT5
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex, Epidermolysis bullosa simplex |
| RS571420165 |
PTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gorlin syndrome, Hereditary cancer-predisposing syndrome |
| RS571432854 |
RERE
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571438309 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, RAI1-related disorder |
| RS571440448 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease, Charcot-Marie-Tooth disease type 4 |
| RS571451076 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS571454176 |
GJB6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 1B, Autosomal dominant nonsyndromic hearing loss 3B |
| RS571456553 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Alstrom syndrome |
| RS571457875 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Cardiomyopathy |
| RS571466270 |
ELP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial dysautonomia, Familial dysautonomia |
| RS571468082 |
TRAPPC9
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571468136 |
FLG
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571471319 |
GNAT1
|
Health Risk |
Pathogenic |
— |
| RS571471435 |
RERE
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with or without anomalies of the brain, eye |
| RS571471637 |
KRT2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS571473762 |
AMPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscle AMP deaminase deficiency, Muscle AMP deaminase deficiency |
| RS571478179 |
LPL
|
Health Risk |
Likely pathogenic |
Hyperlipoproteinemia, type I |
| RS571485213 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, familial |
| RS571488000 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS571489273 |
RXYLT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a |
| RS571493564 |
GYS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disorder due to hepatic glycogen synthase deficiency, Glycogen storage disorder due to hepatic glycogen synthase deficiency |
| RS571497788 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex 5C, with pyloric atresia |
| RS571504063 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS571511652 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS571517554 |
CARD11
|
Health Risk |
Pathogenic |
BENTA disease, Severe combined immunodeficiency due to CARD11 deficiency |
| RS571522834 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS571523023 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS571524382 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS571532949 |
PNPT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571547770 |
PLXNB1
|
Health Risk |
Conflicting classifications of pathogenicity |
PLXNB1-related disorder, PLXNB1-related disorder |
| RS571550652 |
LRPPRC
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital lactic acidosis, Saguenay-Lac-Saint-Jean type |
| RS571551238 |
CRPPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2U, Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies) |
| RS571552794 |
DNAH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571554235 |
CTC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, Inborn genetic diseases |
| RS571555115 |
ABCB4
|
Health Risk |
Likely pathogenic |
Cholestasis, intrahepatic |
| RS571556177 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Inborn genetic diseases |
| RS571559303 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS571560082 |
COQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Coenzyme Q10 deficiency |
| RS571563767 |
FIG4
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease |
| RS571564926 |
USB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS571569206 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS571576756 |
ASS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Citrullinemia type I, Citrullinemia |
| RS571577908 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS571588033 |
INPP5E
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Joubert syndrome 1 |
| RS571588512 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS571594379 |
MYO15A
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 3, Papillary renal cell carcinoma type 1 |
| RS571595612 |
COG8
|
Health Risk |
Conflicting classifications of pathogenicity |
COG8-congenital disorder of glycosylation, COG8-congenital disorder of glycosylation |
| RS571597296 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
COL18A1-related disorder, COL18A1-related disorder |
| RS571603222 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2C, Usher syndrome type 2C |
| RS571613839 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS571617130 |
CRTAP
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type 7, Osteogenesis imperfecta type 7 |
| RS571622542 |
TRAPPC9
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS571622809 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Brittle cornea syndrome 1 |
| RS571625657 |
GALE
|
Health Risk |
Conflicting classifications of pathogenicity |
UDPglucose-4-epimerase deficiency, UDPglucose-4-epimerase deficiency |
| RS571626569 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS571627974 |
SMARCAL1
|
Health Risk |
Pathogenic |
Schimke immuno-osseous dysplasia, Schimke immuno-osseous dysplasia |
| RS571637787 |
CACNB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 4, Cardiovascular phenotype |
| RS571640983 |
MFSD2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Microcephaly 15, primary |
| RS571641824 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS571641878 |
WDPCP
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 15, Bardet-Biedl syndrome |
| RS571644669 |
ALG6
|
Health Risk |
Conflicting classifications of pathogenicity |
ALG6-congenital disorder of glycosylation 1C, Renal cyst |
| RS571644858 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS571645304 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS571646732 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS571654307 |
SAMD11
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS571666221 |
STAT2
|
Health Risk |
Pathogenic |
Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection, Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection |
| RS571668370 |
CDH23
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 1D, Autosomal recessive nonsyndromic hearing loss 12 |
| RS571668582 |
FANCC
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Hereditary cancer-predisposing syndrome |
| RS571671091 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS571686284 |
IFT172
|
Health Risk |
Conflicting classifications of pathogenicity |
Short-rib thoracic dysplasia 10 with or without polydactyly, Retinitis pigmentosa 71 |
| RS571694324 |
FREM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Fraser syndrome 2, Fraser syndrome 2 |
| RS571702144 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS571709285 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, DNAH11-related disorder |
| RS571713474 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS571713476 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS571714796 |
PIGT
|
Health Risk |
Likely pathogenic |
Multiple congenital anomalies-hypotonia-seizures syndrome 3, Multiple congenital anomalies-hypotonia-seizures syndrome 3 |
| RS571722733 |
RFT1
|
Health Risk |
Conflicting classifications of pathogenicity |
RFT1-congenital disorder of glycosylation, RFT1-congenital disorder of glycosylation |