PLXNB1 Chromosome 3
Plexin B1
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What This Gene Does
Enables semaphorin receptor activity. Involved in several processes, including negative regulation of cell adhesion; regulation of cell shape; and semaphorin-plexin signaling pathway. Located in plasma membrane. Part of semaphorin receptor complex. [provided by Alliance of Genome Resources, Jul 2025]
Gene Info
Gene Group
"Plexins|IPT domain containing"
Locus Type
gene with protein product
Location
3p21.31
Ensembl
ENSG00000164050
Associated Conditions (1)
PLXNB1-related disorder
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS571547770 | Health Risk | Conflicting classifications of pathogenicity | PLXNB1-related disorder, PLXNB1-related disorder |