Hypercholesterolemia

Metabolic 2,586 variants 7 genes

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Associated Genes (7)

EPHX2 APOE APOB SORT1 LDLR LDLRAP1 PCSK9

Associated Variants (2,586)

RSID	Gene	Risk Allele	Odds Ratio	Evidence
RS751141	EPHX2	—	—	exploratory
RS7412	APOE	—	—	exploratory
RS569210477	—	T	3.3	moderate
RS13306206	APOB	G	2.5	moderate
RS821840	—	A	1.3	moderate
RS9958734	—	T	1.2	moderate
RS1077835	—	A	1.2	moderate
RS651821	—	T	1.2	moderate
RS550057	—	C	1.2	moderate
RS2980875	—	G	1.1	moderate
RS17672352	—	C	0.9	moderate
RS75214121	—	C	0.9	moderate
RS1501908	—	C	0.9	moderate
RS1260326	—	T	0.9	moderate
RS1883025	—	C	0.8	moderate
RS17244834	—	T	0.8	moderate
RS217184	—	T	0.8	moderate
RS2738464	—	C	0.8	moderate
RS12740374	SORT1	G	0.7	moderate
RS111784051	—	T	0.6	moderate
RS387906307	LDLR	—	—	strong
RS121908326	LDLRAP1	—	—	strong
RS121908325	LDLRAP1	—	—	strong
RS1557703339	LDLRAP1	—	—	strong
RS121908324	LDLRAP1	—	—	strong
RS28942085	LDLR	—	—	strong
RS28942112	PCSK9	—	—	strong
RS67608943	PCSK9	—	—	strong
RS28362286	PCSK9	—	—	strong
RS121908025	LDLR	—	—	strong
RS121908026	LDLR	—	—	strong
RS28942083	LDLR	—	—	strong
RS121908028	LDLR	—	—	strong
RS121908029	LDLR	—	—	strong
RS121908030	LDLR	—	—	strong
RS28942081	LDLR	—	—	strong
RS28941776	LDLR	—	—	strong
RS121908031	LDLR	—	—	strong
RS28942111	PCSK9	—	—	strong
RS387906302	LDLR	—	—	strong
RS387906303	LDLR	—	—	strong
RS121908033	LDLR	—	—	strong
RS121908034	LDLR	—	—	strong
RS387906304	LDLR	—	—	strong
RS387906305	LDLR	—	—	strong
RS121908039	LDLR	—	—	strong
RS121908040	LDLR	—	—	strong
RS121908041	LDLR	—	—	strong
RS121908042	LDLR	—	—	strong
RS145787161	LDLR	—	—	strong

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