RS67608943 PCSK9

Health Risk Chr 1:55046549
Upload your DNA to see your genotype for this variant.
What This Variant Does
"rs67608943, also known as Y142X, is a SNP in the PCSK9 gene. It has been reported in several studies...
Associated Conditions
Low density lipoprotein cholesterol level quantitative trait locus 1
Familial hypercholesterolemia
Hypercholesterolemia
autosomal dominant
3
Cardiovascular phenotype
Low density lipoprotein cholesterol level quantitative trait locus 1
Familial hypercholesterolemia
Hypercholesterolemia
autosomal dominant
3
Cardiovascular phenotype
GWAS Studies (3)
Trait Risk Allele OR / Beta P-value Study
Low density lipoprotein cholesterol levels — OR: 38.4 5E-13 PubMed
Low density lipoprotein cholesterol levels — OR: 0.98 5E-13 PubMed
Total cholesterol levels — OR: 33.93 5E-9 PubMed
Other Variants in PCSK9
rs28942111 rs28942112 rs137852912 rs28362286 rs793888521 rs794728683 rs141502002 rs374603772 rs41297883 rs28362270
Ask Dr. Hemsworth about this variant