| RS768227723 |
ARID1B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS768228172 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant hypocalcemia 1, Familial hypocalciuric hypercalcemia |
| RS768228804 |
SCO2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS768229646 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS768230462 |
NBAS
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS768230831 |
PANK2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pigmentary pallidal degeneration, Pigmentary pallidal degeneration |
| RS768231769 |
IGFALS
|
Health Risk |
Conflicting classifications of pathogenicity |
Short stature due to primary acid-labile subunit deficiency, Short stature due to primary acid-labile subunit deficiency |
| RS768231851 |
IGHMBP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease axonal type 2S, Autosomal recessive distal spinal muscular atrophy 1 |
| RS768233031 |
ALDH7A1
|
Health Risk |
Pathogenic |
Pyridoxine-dependent epilepsy, Pyridoxine-dependent epilepsy |
| RS768233232 |
APC
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS768233248 |
MAN2B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of alpha-mannosidase, Deficiency of alpha-mannosidase |
| RS768233315 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, COL6A3-related disorder |
| RS768233445 |
SGCE
|
Health Risk |
Conflicting classifications of pathogenicity |
Myoclonic dystonia 11, Myoclonic dystonia 11 |
| RS768235246 |
PYCR1
|
Health Risk |
Conflicting classifications of pathogenicity |
PYCR1-related disorder, PYCR1-related disorder |
| RS768235705 |
KLK4
|
Health Risk |
Likely pathogenic |
Amelogenesis imperfecta type 2A1, Amelogenesis imperfecta type 2A1 |
| RS768236474 |
ACADVL
|
Health Risk |
Likely pathogenic |
Very long chain acyl-CoA dehydrogenase deficiency, Very long chain acyl-CoA dehydrogenase deficiency |
| RS768237094 |
TXNDC15
|
Health Risk |
Pathogenic |
Meckel-Gruber syndrome, Meckel syndrome 14 |
| RS768237144 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS768238394 |
APP
|
Health Risk |
Conflicting classifications of pathogenicity |
Alzheimer disease, Cerebral amyloid angiopathy |
| RS768238678 |
CSNK2A1
|
Health Risk |
Likely pathogenic |
Okur-Chung neurodevelopmental syndrome, CSNK2A1-related disorder |
| RS768238895 |
DNAH9
|
Health Risk |
Likely pathogenic |
DNAH9-related disorder, DNAH9-related disorder |
| RS768241184 |
SPAST
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 4, Hereditary spastic paraplegia 4 |
| RS768241563 |
DEPDC5
|
Health Risk |
Pathogenic |
Epilepsy, familial focal |
| RS768241596 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Tuberous sclerosis 2 |
| RS768241743 |
RASA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Capillary malformation-arteriovenous malformation syndrome, RASA1-related disorder |
| RS768242367 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS768242833 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS768243150 |
HTRA1
|
Health Risk |
Pathogenic/Likely pathogenic |
HTRA1-related disorder, CARASIL syndrome |
| RS768244114 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS768245266 |
SLC26A4
|
Health Risk |
Pathogenic |
Pendred syndrome, Autosomal recessive nonsyndromic hearing loss 4 |
| RS768245333 |
COL4A4
|
Health Risk |
Pathogenic |
Autosomal dominant Alport syndrome, Autosomal dominant Alport syndrome |
| RS768245540 |
DOCK6
|
Health Risk |
Pathogenic |
— |
| RS76824727 |
ALDH18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
ALDH18A1-related de Barsy syndrome, Hereditary spastic paraplegia |
| RS768247528 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS768248277 |
HINT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive axonal neuropathy with neuromyotonia, Autosomal recessive axonal neuropathy with neuromyotonia |
| RS768248477 |
POPDC1
|
Health Risk |
Likely pathogenic |
Autosomal recessive limb-girdle muscular dystrophy type 2X, Autosomal recessive limb-girdle muscular dystrophy type 2X |
| RS768249663 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS768250382 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS768253909 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS768255532 |
LRAT
|
Health Risk |
Likely pathogenic |
Leber congenital amaurosis, Leber congenital amaurosis |
| RS768257384 |
MYO15A
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital sensorineural hearing impairment, Autosomal recessive nonsyndromic hearing loss 3 |
| RS768257762 |
IHH
|
Health Risk |
Pathogenic |
Brachydactyly type A1, Brachydactyly type A1 |
| RS768257868 |
MRE11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia-like disorder |
| RS768257998 |
BBS7
|
Health Risk |
Likely pathogenic |
Bardet-Biedl syndrome 7, Bardet-Biedl syndrome 7 |
| RS76825983 |
OPA3
|
Health Risk |
Conflicting classifications of pathogenicity |
3-Methylglutaconic aciduria type 3, Optic atrophy 3 |
| RS768259863 |
BARD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS768260547 |
COL4A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Alport syndrome, Hematuria |
| RS768261185 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS76826147 |
EPHB2
|
Health Risk |
risk factor |
Prostate cancer/brain cancer susceptibility, Prostate cancer/brain cancer susceptibility |
| RS768262653 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS768262862 |
IMPG1
|
Health Risk |
Pathogenic |
— |
| RS768263997 |
COL1A2
|
Health Risk |
Likely pathogenic |
Osteogenesis imperfecta type I, Ehlers-Danlos syndrome |
| RS768265052 |
PKHD1
|
Health Risk |
Likely pathogenic |
Autosomal recessive polycystic kidney disease, Autosomal recessive polycystic kidney disease |
| RS768265149 |
IMPDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS768265778 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, AXIN2-related attenuated familial adenomatous polyposis |
| RS768269251 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS768269976 |
CEP57
|
Health Risk |
Conflicting classifications of pathogenicity |
Mosaic variegated aneuploidy syndrome 2, CEP57-related disorder |
| RS768270021 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS768272302 |
PEX26
|
Health Risk |
Pathogenic/Likely pathogenic |
Peroxisome biogenesis disorder 7A (Zellweger), Peroxisome biogenesis disorder 7B |
| RS768272570 |
MCCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylcrotonyl-CoA carboxylase 2 deficiency, Methylcrotonyl-CoA carboxylase deficiency |
| RS768273248 |
NDUFAF6
|
Health Risk |
Pathogenic |
Mitochondrial complex I deficiency, nuclear type 17 |
| RS768273651 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS768273900 |
MACF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS768275402 |
RYR1
|
Health Risk |
Conflicting classifications of pathogenicity |
RYR1-related disorder, Malignant hyperthermia |
| RS768275798 |
AASS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hyperlysinemia |
| RS768277427 |
KMT2C
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS768278935 |
ABCA4
|
Health Risk |
Pathogenic/Likely pathogenic |
Severe early-childhood-onset retinal dystrophy, Autosomal recessive retinitis pigmentosa |
| RS768280699 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS768281648 |
BACH2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS768283155 |
APC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS768284272 |
POGZ
|
Health Risk |
Conflicting classifications of pathogenicity |
Intellectual disability-microcephaly-strabismus-behavioral abnormalities syndrome, Intellectual disability-microcephaly-strabismus-behavioral abnormalities syndrome |
| RS768284828 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 7 |
| RS768285660 |
DNM2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease dominant intermediate B, Autosomal dominant centronuclear myopathy |
| RS768286024 |
SETBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS768286092 |
PPP1CB
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome, Noonan syndrome |
| RS768286281 |
PKP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 9, Arrhythmogenic right ventricular cardiomyopathy |
| RS768286324 |
KCNJ1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bartter disease type 2, Bartter disease type 2 |
| RS768286574 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS768287089 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS768288230 |
STXBP2
|
Health Risk |
Likely pathogenic |
Familial hemophagocytic lymphohistiocytosis 5, Familial hemophagocytic lymphohistiocytosis 5 |
| RS768289137 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS768290318 |
ALDH3A2
|
Health Risk |
Pathogenic/Likely pathogenic |
Sjögren-Larsson syndrome, Sjögren-Larsson syndrome |
| RS768290597 |
ACTG2
|
Health Risk |
Pathogenic |
Visceral myopathy 1, Visceral myopathy 1 |
| RS768291371 |
IL2RG
|
Health Risk |
Conflicting classifications of pathogenicity |
X-linked severe combined immunodeficiency, X-linked severe combined immunodeficiency |
| RS768291477 |
PDGFRA
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS768292011 |
CHRNA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS768292284 |
CERKL
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa 26, Inborn genetic diseases |
| RS768292803 |
COL6A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS768293070 |
FBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital contractural arachnodactyly, Familial thoracic aortic aneurysm and aortic dissection |
| RS768293167 |
AMT
|
Health Risk |
Likely pathogenic |
Glycine encephalopathy, Glycine encephalopathy |
| RS768294248 |
BSCL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Inborn genetic diseases |
| RS768295360 |
TECTA
|
Health Risk |
Pathogenic |
Rare genetic deafness, Inborn genetic diseases |
| RS768298662 |
MYH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Aortic aneurysm, familial thoracic 4 |
| RS768299251 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS768299416 |
TRMU
|
Health Risk |
Likely pathogenic |
Acute infantile liver failure due to synthesis defect of mtDNA-encoded proteins, Aminoglycoside-induced deafness |
| RS768299417 |
NPC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Niemann-Pick disease, type C |
| RS768299607 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS768299786 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS768300296 |
SPEG
|
Health Risk |
Pathogenic |
Myopathy, centronuclear |
| RS768301915 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 2 |