| RS755263466 |
PALB2
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial cancer of breast, Malignant tumor of breast |
| RS755264102 |
ABCA1
|
Health Risk |
Pathogenic |
— |
| RS755265316 |
GBA1
|
Health Risk |
Likely pathogenic |
Gaucher disease type II, Gaucher disease type II |
| RS755265519 |
RAD51D
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS755265819 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, CREBBP-related disorder |
| RS755267357 |
ATP7B
|
Health Risk |
Likely pathogenic |
Wilson disease, Wilson disease |
| RS755267771 |
DDHD2
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 54, Hereditary spastic paraplegia 54 |
| RS755268691 |
RP1L1
|
Health Risk |
Conflicting classifications of pathogenicity |
Occult macular dystrophy, Occult macular dystrophy |
| RS755269372 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuropathy, hereditary sensory |
| RS755270593 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic cardiomyopathy with wooly hair and keratoderma |
| RS755271052 |
MLC1
|
Health Risk |
Likely pathogenic |
Megalencephalic leukoencephalopathy with subcortical cysts 1, Megalencephalic leukoencephalopathy with subcortical cysts 1 |
| RS755272017 |
MFRP
|
Health Risk |
Likely pathogenic |
Isolated microphthalmia 5, Isolated microphthalmia 5 |
| RS75527207 |
CFTR
|
Health Risk |
Likely pathogenic |
Cystic fibrosis, Hereditary pancreatitis |
| RS755272601 |
CACNB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 5, Episodic ataxia type 5 |
| RS755272769 |
ATR
|
Health Risk |
Likely pathogenic |
— |
| RS755276378 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 11, Cardiovascular phenotype |
| RS755276554 |
ITSN1
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS755276577 |
MPDZ
|
Health Risk |
Pathogenic |
MPDZ-related disorder, MPDZ-related disorder |
| RS755277543 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS755277801 |
CASR
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant hypocalcemia 1, Familial hypocalciuric hypercalcemia |
| RS755278391 |
FOLR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebral folate transport deficiency, Inborn genetic diseases |
| RS755279097 |
GFER
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755279298 |
ARSB
|
Health Risk |
Likely pathogenic |
Mucopolysaccharidosis type 6, Mucopolysaccharidosis type 6 |
| RS755279579 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 42 |
| RS755280013 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Timothy syndrome |
| RS755283040 |
TET2
|
Health Risk |
Pathogenic |
— |
| RS755284496 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |
| RS755284666 |
KCNMA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy-paroxysmal dyskinesia syndrome, Generalized epilepsy-paroxysmal dyskinesia syndrome |
| RS75528494 |
GBA1
|
Health Risk |
Likely pathogenic |
Gaucher disease, Gaucher disease |
| RS755285181 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS755285941 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Sotos syndrome, Sotos syndrome |
| RS755287045 |
MAPK8IP3
|
Health Risk |
Pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS755287192 |
SCNN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudohypoaldosteronism, type IB1 |
| RS755287426 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 4, Spinocerebellar ataxia |
| RS755287627 |
ANK2
|
Health Risk |
Likely pathogenic |
Long QT syndrome, Long QT syndrome |
| RS755288092 |
CANT1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755288504 |
INVS
|
Health Risk |
Pathogenic/Likely pathogenic |
Infantile nephronophthisis, Nephronophthisis |
| RS75528968 |
CFTR
|
Health Risk |
Pathogenic |
Cystic fibrosis, CFTR-related disorder |
| RS755289850 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS755290745 |
EPS8L2
|
Health Risk |
Likely pathogenic |
— |
| RS755291689 |
IDH2
|
Health Risk |
Conflicting classifications of pathogenicity |
D-2-hydroxyglutaric aciduria 2, D-2-hydroxyglutaric aciduria 2 |
| RS755292321 |
CHD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755292491 |
NALCN
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755294265 |
KIDINS220
|
Health Risk |
Likely pathogenic |
Spastic paraplegia, intellectual disability |
| RS755295390 |
PTEN
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, PTEN hamartoma tumor syndrome |
| RS755295556 |
SMARCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Rhabdoid tumor predisposition syndrome 2 |
| RS755298136 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic osteodysplastic primordial dwarfism type II, PCNT-related disorder |
| RS755298693 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 11, Cardiovascular phenotype |
| RS755299132 |
AUH
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylglutaconic aciduria type 1, 3-methylglutaconic aciduria type 1 |
| RS755299634 |
CPAP
|
Health Risk |
Pathogenic |
— |
| RS755299669 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS755300564 |
KCNE3
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 6, Cardiovascular phenotype |
| RS755301027 |
CDKN1B
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Multiple endocrine neoplasia type 4 |
| RS755301795 |
KIF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 30, Neuropathy |
| RS755302593 |
CIITA
|
Health Risk |
Conflicting classifications of pathogenicity |
MHC class II deficiency, MHC class II deficiency |
| RS755303686 |
CHRNE
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital myasthenic syndrome 4A, Congenital myasthenic syndrome |
| RS755304444 |
MYO3A
|
Health Risk |
Pathogenic |
— |
| RS755305281 |
BCS1L
|
Health Risk |
Conflicting classifications of pathogenicity |
GRACILE syndrome, GRACILE syndrome |
| RS755305465 |
GYS1
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycogen storage disease due to muscle and heart glycogen synthase deficiency, Glycogen storage disease due to muscle and heart glycogen synthase deficiency |
| RS755305630 |
DYNC2H1
|
Health Risk |
Pathogenic |
Asphyxiating thoracic dystrophy 3, Jeune thoracic dystrophy |
| RS755306597 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiomyopathy |
| RS755306741 |
SPAG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 28, Primary ciliary dyskinesia |
| RS755306757 |
MYH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Freeman-Sheldon syndrome, Distal arthrogryposis type 2B1 |
| RS755306887 |
PHIP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755307689 |
SRCAP
|
Health Risk |
Likely pathogenic |
Neurodevelopmental disorder, Neurodevelopmental disorder |
| RS755307749 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755308070 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS755308448 |
CPT1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Carnitine palmitoyl transferase 1A deficiency, Carnitine palmitoyl transferase 1A deficiency |
| RS755309416 |
FANCM
|
Health Risk |
Pathogenic |
Fanconi anemia, Fanconi anemia |
| RS755310507 |
ATP1A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hemiplegic migraine, Migraine |
| RS755311638 |
SLC45A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculocutaneous albinism type 4, SKIN/HAIR/EYE PIGMENTATION 5 |
| RS755311871 |
CEBPA
|
Health Risk |
Conflicting classifications of pathogenicity |
Acute myeloid leukemia, Inborn genetic diseases |
| RS755312472 |
NDUFV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leigh syndrome, Mitochondrial complex I deficiency |
| RS755312623 |
POLR3B
|
Health Risk |
Likely pathogenic |
Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism, Hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism |
| RS755312854 |
SLC4A11
|
Health Risk |
Conflicting classifications of pathogenicity |
Corneal dystrophy, Corneal dystrophy |
| RS755313774 |
CTNNA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary diffuse gastric adenocarcinoma |
| RS755313812 |
DDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of aromatic-L-amino-acid decarboxylase, Inborn genetic diseases |
| RS755313904 |
GLDC
|
Health Risk |
Pathogenic/Likely pathogenic |
Glycine encephalopathy, Glycine encephalopathy |
| RS755314355 |
BBS12
|
Health Risk |
Pathogenic/Likely pathogenic |
Bardet-Biedl syndrome 12, Bardet-Biedl syndrome |
| RS755314562 |
RNF168
|
Health Risk |
Pathogenic/Likely pathogenic |
RIDDLE syndrome, RIDDLE syndrome |
| RS755314719 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS755315398 |
POLG
|
Health Risk |
Likely pathogenic |
Progressive sclerosing poliodystrophy, Progressive sclerosing poliodystrophy |
| RS755315693 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Retinitis pigmentosa 80 |
| RS755316066 |
SYNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 5, autosomal dominant |
| RS755317735 |
ARX
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 1 |
| RS755318029 |
KIFBP
|
Health Risk |
Likely pathogenic |
— |
| RS755319650 |
ELP1
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial dysautonomia, Medulloblastoma |
| RS755320741 |
NAF1
|
Health Risk |
Likely risk allele |
Pulmonary fibrosis, Pulmonary fibrosis |
| RS755322593 |
HIVEP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755322616 |
LIFR
|
Health Risk |
Pathogenic |
Connective tissue disorder, Connective tissue disorder |
| RS755322824 |
HRAS
|
Health Risk |
Likely pathogenic |
— |
| RS755323236 |
SCN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Early-infantile DEE, Early-infantile DEE |
| RS755324231 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, myofibrillar |
| RS755324255 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS755325663 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS755325901 |
PDE6B
|
Health Risk |
Pathogenic |
— |
| RS755328181 |
VPS13A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS755328329 |
MCCC1
|
Health Risk |
Conflicting classifications of pathogenicity |
3-methylcrotonyl-CoA carboxylase 1 deficiency, MCCC1-related disorder |
| RS755328574 |
WFS1
|
Health Risk |
Uncertain significance/Uncertain risk allele |
Autosomal dominant nonsyndromic hearing loss 6, WFS1-Related Spectrum Disorders |
| RS755328835 |
VLDLR
|
Health Risk |
Likely pathogenic |
— |