| RS753269143 |
ATM
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Ataxia-telangiectasia syndrome |
| RS75326924 |
CD36
|
Health Risk |
Conflicting classifications of pathogenicity |
Platelet-type bleeding disorder 10, Inherited bleeding disorder |
| RS753270420 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CHARGE syndrome |
| RS753270443 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Arrhythmogenic right ventricular dysplasia 8 |
| RS753270542 |
MYO3A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 30, Inborn genetic diseases |
| RS753270641 |
GHR
|
Health Risk |
Pathogenic |
— |
| RS753271148 |
SCN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Brugada syndrome 5 |
| RS753271305 |
DSP
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic cardiomyopathy with wooly hair and keratoderma, Arrhythmogenic right ventricular dysplasia 8 |
| RS753272712 |
FANCF
|
Health Risk |
Likely pathogenic |
Fanconi anemia complementation group F, Fanconi anemia |
| RS753272955 |
KMT2B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753273893 |
SLC26A5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753275152 |
SETD5
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753275336 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS753275419 |
DDC
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of aromatic-L-amino-acid decarboxylase, Deficiency of aromatic-L-amino-acid decarboxylase |
| RS753276270 |
MSH6
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS753277194 |
PDE6B
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Congenital stationary night blindness autosomal dominant 2 |
| RS753277227 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS753277514 |
SACS
|
Health Risk |
Likely pathogenic |
Charlevoix-Saguenay spastic ataxia, Charlevoix-Saguenay spastic ataxia |
| RS753279446 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Miyoshi muscular dystrophy 1 |
| RS753279755 |
KIF1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS753280668 |
GNRHR
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypogonadotropic hypogonadism 7 with or without anosmia, Hypogonadotropic hypogonadism 7 with or without anosmia |
| RS753280877 |
SLC2A10
|
Health Risk |
Conflicting classifications of pathogenicity |
Arterial tortuosity syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS753282248 |
VPS13B
|
Health Risk |
Pathogenic |
— |
| RS753283086 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome, Inborn genetic diseases |
| RS753283873 |
PEX7
|
Health Risk |
Pathogenic/Likely pathogenic |
Peroxisome biogenesis disorder 9B, Peroxisome biogenesis disorder 9B |
| RS753283972 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, Cardiovascular phenotype |
| RS753284434 |
LETM1
|
Health Risk |
Pathogenic |
LETM1-associated clinical spectrum with predominant nervous system involvement, Neurodegeneration |
| RS753284739 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS753286589 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS753287764 |
SH3TC2
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 4, Susceptibility to mononeuropathy of the median nerve |
| RS753287841 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS753288164 |
DMD
|
Health Risk |
Pathogenic |
Colorectal cancer, Colorectal cancer |
| RS753288303 |
MMUT
|
Health Risk |
Pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic acidemia |
| RS753289059 |
TUBGCP6
|
Health Risk |
Likely pathogenic |
Malignant tumor of urinary bladder, Malignant tumor of urinary bladder |
| RS753289586 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS753289916 |
RELN
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial temporal lobe epilepsy 7, Norman-Roberts syndrome |
| RS753291151 |
WDR19
|
Health Risk |
Likely pathogenic |
Senior-Loken syndrome 8, Asphyxiating thoracic dystrophy 5 |
| RS753291303 |
ALDH3A2
|
Health Risk |
Pathogenic |
— |
| RS75329154 |
ARHGEF6
|
Health Risk |
Conflicting classifications of pathogenicity |
ARHGEF6-related disorder, ARHGEF6-related disorder |
| RS753292024 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypercholesterolemia |
| RS753292241 |
SCN10A
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome, Cardiovascular phenotype |
| RS753293188 |
KRT83
|
Health Risk |
Conflicting classifications of pathogenicity |
Erythrokeratodermia variabilis et progressiva 5, Erythrokeratodermia variabilis et progressiva 5 |
| RS753294770 |
SNTA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS753295868 |
NT5C2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary spastic paraplegia 45, Neurodevelopmental disorder |
| RS753295968 |
LZTR1
|
Health Risk |
Pathogenic/Likely pathogenic |
Noonan syndrome 2, Noonan syndrome 10 |
| RS753296078 |
DPYD
|
Health Risk |
Likely pathogenic |
Dihydropyrimidine dehydrogenase deficiency, Dihydropyrimidine dehydrogenase deficiency |
| RS753296261 |
ABCC8
|
Health Risk |
Pathogenic/Likely pathogenic |
Type 2 diabetes mellitus, Hyperinsulinemic hypoglycemia |
| RS753296393 |
TNFRSF13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, common variable |
| RS753297152 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Inborn genetic diseases |
| RS753299061 |
POLD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS753299915 |
CARD8
|
Health Risk |
Likely pathogenic |
Inflammatory bowel disease 30, Inflammatory bowel disease 30 |
| RS753300178 |
CFAP43
|
Health Risk |
Pathogenic |
Spermatogenic failure 19, Spermatogenic failure 19 |
| RS753300394 |
VPS13A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS753300898 |
MYBPC3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy, Hypertrophic cardiomyopathy 4 |
| RS753301358 |
ALMS1
|
Health Risk |
Pathogenic |
Alstrom syndrome, Alstrom syndrome |
| RS753302494 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS753303277 |
PDE6A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS753306883 |
TOPORS
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753307105 |
PKHD1
|
Health Risk |
Likely pathogenic |
Autosomal recessive polycystic kidney disease, PKHD1-related disorder |
| RS753307279 |
DNAH1
|
Health Risk |
Likely pathogenic |
Non-syndromic male infertility due to sperm motility disorder, Non-syndromic male infertility due to sperm motility disorder |
| RS753307498 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS753307725 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS753308387 |
PROM1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinitis pigmentosa 41 |
| RS753308829 |
CLCN1
|
Health Risk |
Likely pathogenic |
Congenital myotonia, autosomal dominant form |
| RS753308994 |
PIGN
|
Health Risk |
Likely pathogenic |
Multiple congenital anomalies-hypotonia-seizures syndrome 1, Multiple congenital anomalies-hypotonia-seizures syndrome 1 |
| RS753309074 |
CPT1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 73, Hereditary spastic paraplegia 73 |
| RS753312340 |
NDRG1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease, Charcot-Marie-Tooth disease type 4D |
| RS753312969 |
RARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
Pontocerebellar hypoplasia type 6, Pontocerebellar hypoplasia type 6 |
| RS753313121 |
CACNA1S
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant hyperthermia, susceptibility to |
| RS753313462 |
SERPINA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alpha-1-antitrypsin deficiency, Alpha-1-antitrypsin deficiency |
| RS753313963 |
B3GLCT
|
Health Risk |
Conflicting classifications of pathogenicity |
Peters plus syndrome, Peters plus syndrome |
| RS753314164 |
MAK
|
Health Risk |
Pathogenic |
Retinitis pigmentosa, Retinitis pigmentosa 62 |
| RS753314680 |
FAT4
|
Health Risk |
Conflicting classifications of pathogenicity |
FAT4-related disorder, FAT4-related disorder |
| RS753315223 |
HGSNAT
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis, MPS-III-C |
| RS753315599 |
SHH
|
Health Risk |
Likely pathogenic |
Microphthalmia, isolated |
| RS753315808 |
HYCC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypomyelination and Congenital Cataract, Inborn genetic diseases |
| RS753316557 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS753317536 |
EVC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS753317811 |
GPR179
|
Health Risk |
Likely pathogenic |
— |
| RS753319377 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, CREBBP-related disorder |
| RS753324280 |
SLC7A9
|
Health Risk |
Pathogenic/Likely pathogenic |
Cystinuria, Cystinuria |
| RS753324919 |
SPTBN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Spinocerebellar ataxia type 5 |
| RS753324947 |
ASCC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Spinal muscular atrophy with congenital bone fractures 2, See cases |
| RS753324965 |
ABCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypoalphalipoproteinemia, primary |
| RS753325067 |
PKD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753325454 |
ERCC4
|
Health Risk |
Pathogenic |
Xeroderma pigmentosum, group F |
| RS753327806 |
INF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis 5, Charcot-Marie-Tooth disease dominant intermediate E |
| RS753329079 |
ABCC2
|
Health Risk |
Likely pathogenic |
ABCC2-related disorder, ABCC2-related disorder |
| RS753329341 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS753330544 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa |
| RS753330854 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS753331607 |
HCN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 8, Cardiovascular phenotype |
| RS753332305 |
RUNX2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cleidocranial dysostosis, Inborn genetic diseases |
| RS753333359 |
TTN-AS1;TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS753334568 |
TTN
|
Health Risk |
Pathogenic/Likely pathogenic |
Myopathy, myofibrillar |
| RS753334715 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
PIEZO1-related disorder, Inborn genetic diseases |
| RS753334806 |
PEX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Zellweger spectrum disorders, PEX1-related disorder |
| RS753334817 |
BEST1
|
Health Risk |
Pathogenic |
BEST1-related disorder, BEST1-related disorder |
| RS753334968 |
ARID1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS753335678 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |