| RS6733774 |
FAM161A
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa 28 |
| RS67364703 |
COL1A1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta with normal sclerae, dominant form |
| RS67367843 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS6736791 |
NDUFA10
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex I deficiency, nuclear type 1 |
| RS67368147 |
COL1A1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type III, Osteogenesis imperfecta with normal sclerae |
| RS67394386 |
COL1A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Osteogenesis imperfecta type III, Osteogenesis imperfecta type I |
| RS67398234 |
COL1A2
|
Health Risk |
Pathogenic |
Ehlers-Danlos syndrome, arthrochalasia type |
| RS67414444 |
OTC
|
Health Risk |
Pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS67416837 |
COL1A1
|
Health Risk |
Pathogenic |
— |
| RS67418243 |
OTC
|
Health Risk |
Pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS6742078 |
UGT1A1
|
Health Risk |
Benign; association |
BILIRUBIN, SERUM LEVEL OF |
| RS67445413 |
COL1A1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type III, Osteogenesis imperfecta type I |
| RS67468335 |
OTC
|
Health Risk |
Pathogenic/Likely pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS67470842 |
ABCC6
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive inherited pseudoxanthoma elasticum, Autosomal recessive inherited pseudoxanthoma elasticum |
| RS67486158 |
OTC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS6749719 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS67501347 |
OTC
|
Health Risk |
Pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS67507747 |
COL1A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Osteogenesis imperfecta type I, Osteogenesis imperfecta |
| RS6751967 |
IL1RL1
|
Health Risk |
association |
Ascending aortic dissection, Ascending aortic dissection |
| RS6752026 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial hypobetalipoproteinemia 1, Hypercholesterolemia |
| RS67525025 |
COL1A2
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta, perinatal lethal |
| RS67543427 |
COL1A2
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type I, Ehlers-Danlos syndrome |
| RS67543897 |
COL1A1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS6755258 |
TTC7A
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple gastrointestinal atresias, Inborn genetic diseases |
| RS67561842 |
ABCC6
|
Health Risk |
Likely pathogenic |
Autosomal recessive inherited pseudoxanthoma elasticum, Arterial calcification |
| RS67569268 |
COL1A1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS67586389 |
DCTN1
|
Health Risk |
Pathogenic |
Perry syndrome, Neuronopathy |
| RS67606936 |
MMAB;MVK
|
Health Risk |
Conflicting classifications of pathogenicity |
Mevalonic aciduria, Hyperimmunoglobulin D with periodic fever |
| RS67608943 |
PCSK9
|
Health Risk |
Conflicting classifications of pathogenicity |
Low density lipoprotein cholesterol level quantitative trait locus 1, Familial hypercholesterolemia |
| RS67609234 |
COL1A2
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type III, Osteogenesis imperfecta |
| RS67651903 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS67675951 |
COL1A2;COL1A2-AS1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type I, Ehlers-Danlos syndrome |
| RS67682641 |
COL1A1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type III, Osteogenesis imperfecta type I |
| RS67693970 |
COL1A1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta with normal sclerae, dominant form |
| RS67707918 |
COL1A2
|
Health Risk |
Pathogenic/Likely pathogenic |
Osteogenesis imperfecta with normal sclerae, dominant form |
| RS67729041 |
COL1A2
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type III, Osteogenesis imperfecta type III |
| RS67752076 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS67767715 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperinsulinemic hypoglycemia, familial |
| RS67768540 |
COL1A2
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type I, Osteogenesis imperfecta |
| RS67771061 |
COL1A1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta, Osteogenesis imperfecta type I |
| RS67791546 |
ABCC6
|
Health Risk |
Pathogenic |
Autosomal recessive inherited pseudoxanthoma elasticum, Arterial calcification |
| RS67815019 |
COL1A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Osteogenesis imperfecta type I, Osteogenesis imperfecta |
| RS67828806 |
COL1A1
|
Health Risk |
Likely pathogenic |
Osteogenesis imperfecta type 1, mild |
| RS67839036 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS67839039 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS67865220 |
COL1A2
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type I, Ehlers-Danlos syndrome |
| RS67867306 |
ABCC6
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive inherited pseudoxanthoma elasticum, Arterial calcification |
| RS67870244 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS67870245 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS67879854 |
COL1A1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type I, 7 conditions |
| RS67890094 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS67891210 |
COL1A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Osteogenesis imperfecta type I, Osteogenesis imperfecta with normal sclerae |
| RS6790979 |
WNT5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant Robinow syndrome 1, Autosomal dominant Robinow syndrome 1 |
| RS67916658 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS67939114 |
ALDH3A2
|
Health Risk |
Conflicting classifications of pathogenicity |
ALDH3A2-related disorder, Sjögren-Larsson syndrome |
| RS67939655 |
OTC
|
Health Risk |
Pathogenic |
Ornithine carbamoyltransferase deficiency, OTC-related disorder |
| RS67954347 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS67960011 |
OTC
|
Health Risk |
Pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS67965462 |
COL1A1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta, perinatal lethal |
| RS67967266 |
HSPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia, Spastic paraplegia |
| RS67993095 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS68018207 |
SLC22A5
|
Health Risk |
Pathogenic |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS68026851 |
OTC
|
Health Risk |
Likely pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS68031618 |
OTC
|
Health Risk |
Likely pathogenic |
Ornithine carbamoyltransferase deficiency, Inborn genetic diseases |
| RS68033093 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS6804746 |
ACY1
|
Health Risk |
Conflicting classifications of pathogenicity |
Aminoacylase 1 deficiency, ACY1-related disorder |
| RS68058881 |
OTC
|
Health Risk |
Pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS68062484 |
COL1A1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type I |
| RS68063264 |
COL1A2
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta with normal sclerae, dominant form |
| RS68071147 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS68114505 |
COL1A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Osteogenesis imperfecta type I, Osteogenesis imperfecta type III |
| RS68132885 |
COL1A2
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type I, Osteogenesis imperfecta with normal sclerae |
| RS68170503 |
OTC
|
Health Risk |
Pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS68181175 |
COL1A1
|
Health Risk |
Pathogenic |
Osteogenesis imperfecta type I, Osteogenesis imperfecta with normal sclerae |
| RS6848974 |
IDUA
|
Health Risk |
Conflicting classifications of pathogenicity |
Mucopolysaccharidosis type 1, Mucopolysaccharidosis type 1 |
| RS6850908 |
DOK7
|
Health Risk |
Likely pathogenic |
Fetal akinesia deformation sequence 3, Fetal akinesia deformation sequence 3 |
| RS6874630 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease type 4C |
| RS6880264 |
DNAH5
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS690016537 |
FAM136A
|
Health Risk |
Pathogenic |
Meniere disease, Meniere disease |
| RS690016538 |
BRCA2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Breast-ovarian cancer |
| RS690016539 |
BRCA2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Breast-ovarian cancer |
| RS690016540 |
BRCA2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Breast-ovarian cancer |
| RS690016541 |
BRCA2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Breast-ovarian cancer |
| RS690016542 |
BRCA2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Breast-ovarian cancer |
| RS690016543 |
SBF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4B3, Charcot-Marie-Tooth disease |
| RS690016544 |
STUB1
|
Health Risk |
Likely pathogenic |
Autosomal recessive spinocerebellar ataxia 16, Spinocerebellar ataxia 48 |
| RS690016545 |
KIF5A
|
Health Risk |
Pathogenic |
Hereditary spastic paraplegia 10, Hereditary spastic paraplegia 10 |
| RS690016546 |
CSF1R
|
Health Risk |
Pathogenic |
Hereditary diffuse leukoencephalopathy with spheroids, Hereditary diffuse leukoencephalopathy with spheroids |
| RS690016548 |
CSF1R
|
Health Risk |
Pathogenic |
Hereditary diffuse leukoencephalopathy with spheroids, CSF1R-related disorder |
| RS690016549 |
CSF1R
|
Health Risk |
Likely pathogenic |
— |
| RS690016551 |
CSF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse leukoencephalopathy with spheroids, Hereditary diffuse leukoencephalopathy with spheroids |
| RS690016554 |
CSF1R
|
Health Risk |
Pathogenic |
Hereditary diffuse leukoencephalopathy with spheroids, Hereditary diffuse leukoencephalopathy with spheroids |
| RS690016556 |
CSF1R
|
Health Risk |
Likely pathogenic |
Hereditary diffuse leukoencephalopathy with spheroids, Hereditary diffuse leukoencephalopathy with spheroids |
| RS690016562 |
CSF1R
|
Health Risk |
Pathogenic |
Hereditary diffuse leukoencephalopathy with spheroids, Hereditary diffuse leukoencephalopathy with spheroids |
| RS690016564 |
CSF1R
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse leukoencephalopathy with spheroids, Brain abnormalities |
| RS6925845 |
MYO6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 22, Autosomal recessive nonsyndromic hearing loss 37 |
| RS6926133 |
FKBP5
|
Health Risk |
Likely risk allele |
Susceptibility to severe depressive disorder, Susceptibility to severe depressive disorder |
| RS6929137 |
CCDC170
|
Health Risk |
Conflicting classifications of pathogenicity |
Estrogen resistance syndrome, CCDC170-related condition |
| RS696217 |
GHRL
|
Health Risk |
Conflicting classifications of pathogenicity |
Metabolic syndrome, susceptibility to |
| RS6972869 |
PMS2
|
Health Risk |
Pathogenic |
Hereditary nonpolyposis colorectal neoplasms, Hereditary cancer-predisposing syndrome |