RS6742078 UGT1A1

Health Risk Chr 2:233763993
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What This Variant Does
"Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cance...
Associated Conditions
GWAS Studies (20)
Trait Risk Allele OR / Beta P-value Study
Bilirubin levels T OR: 0.23 5E-324 PubMed
Plasma bilirubin degradation product, C17H18N2O4 (2)** levels in chronic kidney disease T OR: 0.44 4E-195 PubMed
Bilirubin levels OR: 0.18 1E-158 PubMed
Bilirubin degradation product, C17H20N2O5 (1) levels T OR: 0.39 9E-135 PubMed
Bilirubin levels OR: 0.17 2E-78 PubMed
Direct bilirubin levels x insomnia interaction 3E-69 PubMed
Total bilirubin levels x insomnia interaction 3E-69 PubMed
UDP-glucuronosyltransferase 1-6 levels T OR: 0.24 6E-69 PubMed
Serum metabolite levels β: 0.086 2E-38 PubMed
Serum levels of protein UGT1A6 T OR: 0.26 2E-36 PubMed
Total bilirubin x commonly-tested environments (Sex, Age, Ever-drinking, Ever-smoking, and Current-smoking) interaction T 2E-30 PubMed
Total bilirubin levels T OR: 0.53 4E-28 PubMed
Circulating cell-free DNA T OR: 0.34 2E-23 PubMed
Abnormal results of function study of liver (PheCode 573.7) G β: 0.072 1E-21 PubMed
Total bilirubin x current-smoking interaction T β: 0.047 1E-21 PubMed
Bilirubin (z,z) levels OR: 0.73 3E-20 PubMed
Serum levels of protein CKAP4 T OR: 0.19 1E-19 PubMed
X-11530 levels OR: 0.68 4E-17 PubMed
X-24849 levels OR: 0.72 3E-16 PubMed
X-21448 levels OR: 0.79 5E-16 PubMed
Other Variants in UGT1A1
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