| RS61755813 |
PRPH2
|
Health Risk |
Pathogenic |
Patterned macular dystrophy 1, Cone-rod dystrophy |
| RS61755814 |
PRPH2
|
Health Risk |
Pathogenic |
Macular dystrophy, Stargardt disease |
| RS61755815 |
PRPH2
|
Health Risk |
Pathogenic |
Retinal dystrophy, Retinal dystrophy |
| RS61755816 |
PRPH2
|
Health Risk |
Pathogenic/Likely pathogenic |
Retinitis pigmentosa 7, Retinal dystrophy |
| RS61755817 |
PRPH2
|
Health Risk |
Likely pathogenic |
Retinitis pigmentosa, Vitelliform macular dystrophy 3 |
| RS61755907 |
SH3PXD2B
|
Health Risk |
Pathogenic |
— |
| RS61755909 |
DNAAF5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS61755997 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Connective tissue disorder, Aortic valve disease 1 |
| RS61756006 |
NSD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Sotos syndrome |
| RS61756136 |
ORC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Meier-Gorlin syndrome 1, ORC1-related disorder |
| RS61756137 |
ORC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Meier-Gorlin syndrome 1, Meier-Gorlin syndrome 1 |
| RS61756139 |
ORC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Meier-Gorlin syndrome 1, ORC1-related disorder |
| RS61756146 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS61756147 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS61756177 |
SOX10
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS61756249 |
TNPO3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant limb-girdle muscular dystrophy type 1F, TNPO3-related disorder |
| RS61756250 |
TNPO3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant limb-girdle muscular dystrophy type 1F, TNPO3-related disorder |
| RS61756286 |
CDK5RAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 3, primary |
| RS61756293 |
CENPE
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS61756328 |
BAG3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Dilated cardiomyopathy 1HH |
| RS61756352 |
TRAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
HER2 positive breast carcinoma, TRAP1-related disorder |
| RS61756403 |
POLH
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum variant type, Xeroderma pigmentosum variant type |
| RS61756416 |
PPM1D
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, PPM1D-related disorder |
| RS61756421 |
PPP1R12A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hepatocellular carcinoma, Hepatocellular carcinoma |
| RS61756463 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS61756465 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary nonpolyposis colorectal neoplasms, Hereditary nonpolyposis colon cancer |
| RS61756469 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary nonpolyposis colorectal neoplasms |
| RS61756692 |
CNGA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Achromatopsia 2, Achromatopsia 2 |
| RS61756766 |
TNFRSF13C
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency, common variable |
| RS61757096 |
ITGA6
|
Health Risk |
Conflicting classifications of pathogenicity |
Junctional epidermolysis bullosa with pyloric atresia, ITGA6-related disorder |
| RS61757108 |
ITPR1
|
Health Risk |
Conflicting classifications of pathogenicity |
ITPR1-related disorder, ITPR1-related disorder |
| RS61757111 |
ITPR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant cerebellar ataxia, Autosomal dominant cerebellar ataxia |
| RS61757218 |
DNAH8
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Spermatogenic failure 46 |
| RS61757375 |
EPAS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Erythrocytosis, familial |
| RS61757383 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group A |
| RS61757384 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group A |
| RS61757397 |
FMO3
|
Health Risk |
Likely pathogenic |
Trimethylaminuria, Trimethylaminuria |
| RS61757472 |
ADAMTS10
|
Health Risk |
Conflicting classifications of pathogenicity |
Weill-Marchesani syndrome, Weill-Marchesani syndrome |
| RS61757480 |
ADAMTS3
|
Health Risk |
Pathogenic |
Hennekam lymphangiectasia-lymphedema syndrome 3, Hennekam lymphangiectasia-lymphedema syndrome 3 |
| RS61757582 |
DHCR7
|
Health Risk |
Likely pathogenic |
Smith-Lemli-Opitz syndrome, Inborn genetic diseases |
| RS61757585 |
DHX30
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with severe motor impairment and absent language, Inborn genetic diseases |
| RS61757616 |
DLL1
|
Health Risk |
Conflicting classifications of pathogenicity |
DLL1-related disorder, Thyroid cancer |
| RS61757643 |
BRIP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS61757664 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome 11, Cardiovascular phenotype |
| RS61757671 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS61757674 |
AKAP9
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS61757683 |
ALDH4A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperprolinemia type 2, Hyperprolinemia type 2 |
| RS61757685 |
ALDH7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pyridoxine-dependent epilepsy, Inborn genetic diseases |
| RS61757689 |
ALDOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary fructosuria, ALDOB-related disorder |
| RS61757825 |
RAB18
|
Health Risk |
Conflicting classifications of pathogenicity |
Warburg micro syndrome 3, RAB18-related disorder |
| RS61758020 |
PIK3C2B
|
Health Risk |
Conflicting classifications of pathogenicity |
PIK3C2B-related disorder, PIK3C2B-related disorder |
| RS61758084 |
TPO
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of iodide peroxidase, Deficiency of iodide peroxidase |
| RS61758118 |
TRPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastric cancer, Gastric cancer |
| RS61758122 |
TRPA1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS61758125 |
TRPS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Trichorhinophalangeal syndrome, type III |
| RS61758195 |
MME
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease axonal type 2T, Charcot-Marie-Tooth disease axonal type 2T |
| RS61758368 |
CDK5RAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 3, primary |
| RS61758376 |
VHL
|
Health Risk |
Conflicting classifications of pathogenicity |
Chuvash polycythemia, Von Hippel-Lindau syndrome |
| RS61758405 |
TYRP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Oculocutaneous albinism type 3, TYRP1-related disorder |
| RS61758415 |
DNAH8
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, DNAH8-related disorder |
| RS61758433 |
DNMT3B
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency-centromeric instability-facial anomalies syndrome 1, Centromeric instability of chromosomes 1 |
| RS61758444 |
DPYS
|
Health Risk |
Pathogenic/Likely pathogenic |
Dihydropyrimidinase deficiency, Dihydropyrimidinase deficiency |
| RS61758518 |
NPR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Acromesomelic dysplasia 1, Maroteaux type |
| RS61758531 |
NPR2
|
Health Risk |
Pathogenic/Likely pathogenic |
Acromesomelic dysplasia 1, Maroteaux type |
| RS61758785 |
RAD51B
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, RAD51B-related disorder |
| RS61758858 |
SCNN1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Bronchiectasis with or without elevated sweat chloride 2, Pseudohypoaldosteronism |
| RS61758863 |
AMPD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Muscle AMP deaminase deficiency, AMPD1-related disorder |
| RS61758865 |
ANK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spherocytosis type 1, Spherocytosis |
| RS61758866 |
ANK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spherocytosis type 1, Spherocytosis |
| RS61758977 |
GHR
|
Health Risk |
Conflicting classifications of pathogenicity |
GHR-related disorder, Inborn genetic diseases |
| RS61758992 |
GPSM2
|
Health Risk |
Conflicting classifications of pathogenicity |
GPSM2-related disorder, GPSM2-related disorder |
| RS61758996 |
GRIN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Landau-Kleffner syndrome, Landau-Kleffner syndrome |
| RS61759469 |
CHD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy 94, Inborn genetic diseases |
| RS61759495 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Rubinstein-Taybi syndrome due to CREBBP mutations, Rubinstein-Taybi syndrome |
| RS61759860 |
SCNN1A
|
Health Risk |
Pathogenic |
Bronchiectasis with or without elevated sweat chloride 2, Bronchiectasis with or without elevated sweat chloride 2 |
| RS61759892 |
RECQL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Baller-Gerold syndrome, Hereditary cancer-predisposing syndrome |
| RS61759913 |
SCNN1A
|
Health Risk |
Pathogenic/Likely pathogenic |
Neurodevelopmental delay, Renal tubulopathies |
| RS61759916 |
SCNN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Pseudohypoaldosteronism, type IB1 |
| RS61759917 |
SCNN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Liddle syndrome 1, Pseudohypoaldosteronism |
| RS61760162 |
ERCC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cockayne syndrome, Fanconi anemia complementation group Q |
| RS61760163 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
7 conditions, Inborn genetic diseases |
| RS61760166 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebrooculofacioskeletal syndrome 1, Cockayne syndrome type 2 |
| RS61760167 |
ERCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Cockayne syndrome type 2, Cerebrooculofacioskeletal syndrome 1 |
| RS61760172 |
ESRRB
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 35, ESRRB-related disorder |
| RS61760194 |
UBE3B
|
Health Risk |
Pathogenic |
— |
| RS61760905 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Spastic paraplegia, Inborn genetic diseases |
| RS61760965 |
PCCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Propionic acidemia, Sarcoma |
| RS61760967 |
PCK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Phosphoenolpyruvate carboxykinase deficiency, cytosolic |
| RS61761068 |
PIK3R5
|
Health Risk |
Conflicting classifications of pathogenicity |
Ataxia with oculomotor apraxia type 3, Ataxia with oculomotor apraxia type 3 |
| RS61761321 |
EDAR
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypohidrotic ectodermal dysplasia, Non-syndromic oligodontia |
| RS61761620 |
WDR11
|
Health Risk |
Conflicting classifications of pathogenicity |
WDR11-related disorder, WDR11-related disorder |
| RS61761632 |
XPO1
|
Health Risk |
Conflicting classifications of pathogenicity |
XPO1-associated Neurodevelopmental Disorder, XPO1-associated Neurodevelopmental Disorder |
| RS61761869 |
SERPINA1
|
Health Risk |
Pathogenic/Likely pathogenic |
Alpha-1-antitrypsin deficiency, Alpha-1-antitrypsin deficiency |
| RS61761944 |
SKIC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Trichohepatoenteric syndrome 2, Trichohepatoenteric syndrome 2 |
| RS61762293 |
RPS19
|
Health Risk |
Pathogenic |
Diamond-Blackfan anemia 1, Diamond-Blackfan anemia |
| RS61762303 |
GCH1
|
Health Risk |
Pathogenic |
Dystonia 5, GTP cyclohydrolase I deficiency |
| RS61762498 |
GH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Decreased response to growth hormone stimulation test, Decreased response to growth hormone stimulation test |
| RS61762969 |
XRCC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Colon cancer, Hereditary cancer-predisposing syndrome |
| RS61764068 |
BBS9
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome, Bardet-Biedl syndrome 9 |
| RS6177 |
GHR
|
Health Risk |
Conflicting classifications of pathogenicity |
Short stature due to partial GHR deficiency, Laron-type isolated somatotropin defect |