| RS577894144 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS577902897 |
LARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS577913880 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, ZNF469-related disorder |
| RS577915245 |
RAB3GAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
RAB3GAP1-related disorder, Inborn genetic diseases |
| RS577915581 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS577919981 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Endometrial carcinoma |
| RS577921112 |
DYSF
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuromuscular disease caused by qualitative or quantitative defects of dysferlin, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS577922766 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
PIEZO1-related disorder, Inborn genetic diseases |
| RS577929869 |
RET
|
Health Risk |
Pathogenic |
Multiple endocrine neoplasia, type 2 |
| RS577932201 |
RPGRIP1
|
Health Risk |
Pathogenic |
Retinal dystrophy, Leber congenital amaurosis 6 |
| RS577932894 |
LRP5
|
Health Risk |
Likely pathogenic |
— |
| RS577934998 |
LDLR
|
Health Risk |
Likely pathogenic |
Hypercholesterolemia, familial |
| RS577936545 |
LAMA2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMA2-related muscular dystrophy, LAMA2-related muscular dystrophy |
| RS577938494 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Rare genetic deafness, Usher syndrome |
| RS577939684 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS577940601 |
NF2
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 2 |
| RS577945739 |
BRAT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neonatal-onset encephalopathy with rigidity and seizures, Inborn genetic diseases |
| RS577952179 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS577954688 |
HADH
|
Health Risk |
Uncertain significance/Uncertain risk allele |
Hyperinsulinemic hypoglycemia, familial |
| RS577957158 |
NBEAL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Gray platelet syndrome, Inborn genetic diseases |
| RS577958629 |
TSEN54
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS577964890 |
NKX6-2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS577968084 |
GCK
|
Health Risk |
Conflicting classifications of pathogenicity |
Maturity-onset diabetes of the young type 2, Transient Neonatal Diabetes |
| RS577969558 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS57797061 |
FLNC
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Hypertrophic cardiomyopathy 26 |
| RS577972555 |
DST
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex 3, localized or generalized intermediate |
| RS577973228 |
RIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS577979265 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS577983461 |
MAPKBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS577991475 |
TNRC18
|
Health Risk |
Conflicting classifications of pathogenicity |
Ovarian serous cystadenocarcinoma, Thyroid cancer |
| RS578012528 |
THOC6
|
Health Risk |
Pathogenic |
THOC6-related developmental delay-microcephaly-facial dysmorphism syndrome, THOC6-related developmental delay-microcephaly-facial dysmorphism syndrome |
| RS578013785 |
VDR
|
Health Risk |
Conflicting classifications of pathogenicity |
Vitamin D-dependent rickets type II with alopecia, Vitamin D-dependent rickets type II with alopecia |
| RS578014563 |
DUOX2
|
Health Risk |
Pathogenic/Likely pathogenic |
Thyroid dyshormonogenesis 6, Thyroid dyshormonogenesis 6 |
| RS578020342 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Arrhythmogenic right ventricular dysplasia 2 |
| RS57802288 |
KRT83
|
Health Risk |
Likely pathogenic |
Monilethrix-3, Monilethrix |
| RS578023308 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS578023593 |
ALDH5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS578024729 |
TRDN
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 5, Cardiovascular phenotype |
| RS578030952 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, PKHD1-related disorder |
| RS578033982 |
PACS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Schuurs-Hoeijmakers syndrome, Inborn genetic diseases |
| RS578048957 |
ALDOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary fructosuria, Hereditary fructosuria |
| RS578056399 |
SGCD
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2F, Cardiomyopathy |
| RS578069093 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse gastric adenocarcinoma, Hereditary cancer-predisposing syndrome |
| RS578073937 |
GPIHBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS578085621 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS578086869 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS578091032 |
VHL
|
Health Risk |
Conflicting classifications of pathogenicity |
Von Hippel-Lindau syndrome, Chuvash polycythemia |
| RS578091934 |
RMRP
|
Health Risk |
Conflicting classifications of pathogenicity |
Anauxetic dysplasia, RMRP-related disorder |
| RS578092914 |
PRF1
|
Health Risk |
Pathogenic |
Familial hemophagocytic lymphohistiocytosis 2, PRF1-related disorder |
| RS578095133 |
NTRK1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary insensitivity to pain with anhidrosis, Inborn genetic diseases |
| RS578102641 |
MFSD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis 7, Neuronal ceroid lipofuscinosis 7 |
| RS578112440 |
TNFRSF1A
|
Health Risk |
Conflicting classifications of pathogenicity |
TNF receptor-associated periodic fever syndrome (TRAPS), TNF receptor-associated periodic fever syndrome (TRAPS) |
| RS578113271 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Endometrial carcinoma |
| RS578116271 |
C3
|
Health Risk |
Conflicting classifications of pathogenicity |
Age related macular degeneration 9, Complement component 3 deficiency |
| RS578118592 |
VARS2
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS578127995 |
COL6A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, Bethlem myopathy 1A |
| RS578128759 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 3 |
| RS578137786 |
COL11A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS578140620 |
FAT4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS578141234 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS578153138 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 7 |
| RS578156841 |
AXIN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Oligodontia-cancer predisposition syndrome, Hereditary cancer-predisposing syndrome |
| RS578166707 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS578166720 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
MYH7-related skeletal myopathy, Hypertrophic cardiomyopathy |
| RS578184315 |
FLG
|
Health Risk |
Pathogenic/Likely pathogenic |
Ichthyosis vulgaris, Dermatitis |
| RS578185749 |
DEPDC5
|
Health Risk |
Pathogenic |
Epilepsy, familial focal |
| RS578187010 |
ZFP57
|
Health Risk |
Conflicting classifications of pathogenicity |
Diabetes mellitus, transient neonatal |
| RS578189296 |
ADAM17
|
Health Risk |
Conflicting classifications of pathogenicity |
Inflammatory skin and bowel disease, neonatal |
| RS578189699 |
COQ8A
|
Health Risk |
Likely pathogenic |
Autosomal recessive ataxia due to ubiquinone deficiency, Autosomal recessive ataxia due to ubiquinone deficiency |
| RS578191306 |
DES
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurogenic scapuloperoneal syndrome, Kaeser type |
| RS578191491 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Myopathy |
| RS578193315 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS578199793 |
POMT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A1 |
| RS578202936 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS578204135 |
LTBP4
|
Health Risk |
Conflicting classifications of pathogenicity |
Cutis laxa with severe pulmonary, gastrointestinal and urinary anomalies |
| RS578205635 |
SLC35A1
|
Health Risk |
Pathogenic/Likely pathogenic |
SLC35A1-congenital disorder of glycosylation, SLC35A1-congenital disorder of glycosylation |
| RS578207030 |
PNKP
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 12 |
| RS578214371 |
COQ9
|
Health Risk |
Conflicting classifications of pathogenicity |
Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome, Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome |
| RS578218280 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS578222814 |
PIDD1
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual developmental disorder, autosomal recessive 75 |
| RS578226820 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinoblastoma, Hereditary cancer-predisposing syndrome |
| RS578228721 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Familial thoracic aortic aneurysm and aortic dissection |
| RS578233776 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS578234038 |
CFAP74
|
Health Risk |
Likely pathogenic |
Ciliary dyskinesia, primary |
| RS578239628 |
MYF6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant centronuclear myopathy, Autosomal dominant centronuclear myopathy |
| RS578245415 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS578245757 |
GAA
|
Health Risk |
Conflicting classifications of pathogenicity |
Glycogen storage disease, type II |
| RS57830985 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial partial lipodystrophy, Dunnigan type |
| RS57837128 |
KRT1
|
Health Risk |
Pathogenic/Likely pathogenic |
Annular epidermolytic ichthyosis, Ichthyosis |
| RS57845028 |
KRT5
|
Health Risk |
Likely pathogenic |
— |
| RS57848467 |
NEFL
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease, dominant intermediate G |
| RS57872071 |
KRT3
|
Health Risk |
Pathogenic |
Corneal dystrophy, Meesmann |
| RS57890479 |
KRT5
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex 2A, generalized severe |
| RS57901307 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Charcot-Marie-Tooth disease type 2 |
| RS57920071 |
LMNA
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial partial lipodystrophy, Dunnigan type |
| RS57932685 |
TMEM216
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Joubert syndrome 2 |
| RS57946868 |
GJA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Syndactyly type 3, Oculodentodigital dysplasia |
| RS57955682 |
DES
|
Health Risk |
Likely pathogenic |
Desmin-related myofibrillar myopathy, Limb-girdle muscular dystrophy |
| RS57959072 |
KRT1
|
Health Risk |
Pathogenic |
Epidermolytic ichthyosis, Epidermolytic ichthyosis |
| RS57965306 |
DES
|
Health Risk |
Pathogenic |
Neurogenic scapuloperoneal syndrome, Kaeser type |