| RS587654671 |
NOTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
NOTCH2-related disorder, Hajdu-Cheney syndrome |
| RS587663163 |
CTSK
|
Health Risk |
Pathogenic/Likely pathogenic |
Pyknodysostosis, Pyknodysostosis |
| RS58766676 |
KRT5
|
Health Risk |
Pathogenic |
Epidermolysis bullosa, Epidermolysis bullosa |
| RS587669420 |
SURF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leigh syndrome, Leigh syndrome |
| RS587671725 |
TSPEAR
|
Health Risk |
Likely pathogenic |
— |
| RS587680396 |
HYAL1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of hyaluronoglucosaminidase, Deficiency of hyaluronoglucosaminidase |
| RS587684563 |
PRUNE1
|
Health Risk |
Likely pathogenic |
PRUNE1-related disorder, PRUNE1-related disorder |
| RS587687884 |
PRPF31
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS587688416 |
HMGCS2
|
Health Risk |
Likely pathogenic |
3-hydroxy-3-methylglutaryl-CoA synthase deficiency, 3-hydroxy-3-methylglutaryl-CoA synthase deficiency |
| RS587690535 |
TSPEAR
|
Health Risk |
Likely pathogenic |
Tooth agenesis, selective |
| RS587696191 |
ADAMTSL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Ectopia lentis 2, isolated |
| RS587697719 |
NOTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hajdu-Cheney syndrome, NOTCH2-related disorder |
| RS587699821 |
SURF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leigh syndrome, Leigh syndrome |
| RS587701622 |
ADAMTS13
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS587704985 |
PRPF3
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Inborn genetic diseases |
| RS587705831 |
PACS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS587707561 |
CNOT3
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS587717339 |
TSPEAR
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 98, Tooth agenesis |
| RS587718458 |
NOTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hajdu-Cheney syndrome, Hajdu-Cheney syndrome |
| RS587720574 |
ADAMTSL4
|
Health Risk |
Conflicting classifications of pathogenicity |
Ectopia lentis 2, isolated |
| RS587726240 |
CACNA2D2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cerebellar atrophy with seizures and variable developmental delay, Early-infantile DEE |
| RS587727388 |
HMGCS2
|
Health Risk |
Pathogenic |
3-hydroxy-3-methylglutaryl-CoA synthase deficiency, 3-hydroxy-3-methylglutaryl-CoA synthase deficiency |
| RS587731307 |
ZMYND10
|
Health Risk |
Pathogenic |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS587731325 |
PHGDH
|
Health Risk |
Conflicting classifications of pathogenicity |
PHGDH deficiency, Neu-Laxova syndrome 1 |
| RS587735797 |
NOTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
NOTCH2-related disorder, Inborn genetic diseases |
| RS587744329 |
CNOT3
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS587745743 |
PACS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS587748556 |
NOTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hajdu-Cheney syndrome, NOTCH2-related disorder |
| RS587750566 |
ADAMTS13
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS587753385 |
SURF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Leigh syndrome, Leigh syndrome |
| RS587757028 |
PRPF31
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinitis pigmentosa |
| RS587764801 |
PEX11B
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS587767779 |
ADAMTSL4
|
Health Risk |
Pathogenic |
— |
| RS587767936 |
CNOT3
|
Health Risk |
Likely pathogenic |
— |
| RS587768675 |
ADAMTS13
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS587771241 |
SLURP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Acroerythrokeratoderma, Acroerythrokeratoderma |
| RS587775302 |
PACS2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS587775407 |
CTSK
|
Health Risk |
Likely pathogenic |
Pyknodysostosis, Pyknodysostosis |
| RS587776350 |
PAX9
|
Health Risk |
Pathogenic |
Tooth agenesis, selective |
| RS587776351 |
BRCA2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Breast-ovarian cancer |
| RS587776384 |
SLC27A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Lamellar ichthyosis, Ichthyosis prematurity syndrome |
| RS587776398 |
CDH1
|
Health Risk |
Pathogenic |
Hereditary diffuse gastric adenocarcinoma, CDH1-related diffuse gastric and lobular breast cancer syndrome |
| RS587776401 |
COL4A5
|
Health Risk |
Pathogenic/Likely pathogenic |
X-linked Alport syndrome, X-linked Alport syndrome |
| RS587776402 |
COL4A5
|
Health Risk |
Pathogenic/Likely pathogenic |
X-linked Alport syndrome, X-linked Alport syndrome |
| RS587776403 |
COL4A5
|
Health Risk |
Likely pathogenic |
X-linked Alport syndrome, X-linked Alport syndrome |
| RS587776404 |
COL4A5
|
Health Risk |
Pathogenic |
— |
| RS587776405 |
PALB2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS587776406 |
PALB2
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS587776407 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS587776408 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS587776409 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS587776410 |
PALB2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS587776411 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS587776412 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS587776413 |
PALB2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS587776414 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS587776415 |
PALB2
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS587776416 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS587776417 |
PALB2
|
Health Risk |
Likely pathogenic |
Pancreatic cancer, susceptibility to |
| RS587776418 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS587776419 |
PALB2
|
Health Risk |
Pathogenic/Likely pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS587776420 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS587776423 |
PALB2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS587776424 |
PALB2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS587776425 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS587776426 |
PALB2
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS587776427 |
PALB2
|
Health Risk |
Pathogenic |
Familial cancer of breast, Familial cancer of breast |
| RS587776428 |
PALB2
|
Health Risk |
Pathogenic/Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS587776429 |
SALL2
|
Health Risk |
Pathogenic |
Coloboma, ocular |
| RS587776434 |
MT-ND1
|
Health Risk |
Likely pathogenic |
Leigh syndrome, Mitochondrial disease |
| RS587776438 |
MT-ND3
|
Health Risk |
Likely pathogenic |
Leigh syndrome, Mitochondrial disease |
| RS587776440 |
MT-ND5
|
Health Risk |
Likely pathogenic |
Leigh syndrome, Mitochondrial disease |
| RS587776441 |
MT-TV
|
Health Risk |
Likely pathogenic |
MELAS syndrome, Mitochondrial disease |
| RS587776445 |
HTRA1
|
Health Risk |
Likely pathogenic |
CARASIL syndrome, CARASIL syndrome |
| RS587776446 |
HTRA1
|
Health Risk |
Conflicting classifications of pathogenicity |
CARASIL syndrome, HTRA1-related cerebral small vessel disease |
| RS587776448 |
HTRA1
|
Health Risk |
Pathogenic |
CARASIL syndrome, CARASIL syndrome |
| RS587776451 |
GATA1
|
Health Risk |
Pathogenic |
Thrombocytopenia, X-linked |
| RS587776452 |
GATA1
|
Health Risk |
Pathogenic |
X-linked dyserythropoetic anemia with abnormal platelets and neutropenia, Thrombocytopenia |
| RS587776453 |
GATA1
|
Health Risk |
Pathogenic |
X-linked dyserythropoetic anemia with abnormal platelets and neutropenia, Thrombocytopenia |
| RS587776454 |
GATA1
|
Health Risk |
Conflicting classifications of pathogenicity |
GATA binding protein 1 related thrombocytopenia with dyserythropoiesis, Diamond-Blackfan anemia |
| RS587776456 |
GATA1
|
Health Risk |
Likely pathogenic |
Thrombocytopenia, X-linked |
| RS587776457 |
NAA10
|
Health Risk |
Pathogenic |
Microphthalmia, syndromic 1 |
| RS587776459 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS587776460 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS587776464 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS587776466 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS587776467 |
BRCA2
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS587776468 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS587776469 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS587776471 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS587776472 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS587776473 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS587776476 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Breast-ovarian cancer |
| RS587776478 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS587776480 |
BRCA1
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS587776481 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS587776482 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS587776484 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |
| RS587776485 |
BRCA1
|
Health Risk |
Pathogenic |
Breast-ovarian cancer, familial |
| RS587776487 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast-ovarian cancer, familial |