| RS575922741 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Stiff skin syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS575926270 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, KIT-related disorder |
| RS575928986 |
TET2
|
Health Risk |
Pathogenic |
EBV-positive nodal T- and NK-cell lymphoma, EBV-positive nodal T- and NK-cell lymphoma |
| RS575937427 |
SH3TC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease type 4C |
| RS575938861 |
DNAJB6
|
Health Risk |
Likely pathogenic |
Autosomal dominant limb-girdle muscular dystrophy type 1D (DNAJB6), Autosomal dominant limb-girdle muscular dystrophy type 1D (DNAJB6) |
| RS575939045 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS575939496 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS575944941 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS575947038 |
KRT6C
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS575957641 |
BBS10
|
Health Risk |
Conflicting classifications of pathogenicity |
Bardet-Biedl syndrome 10, Bardet-Biedl syndrome |
| RS575958060 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS575959163 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia, autosomal recessive |
| RS575962845 |
PEPD
|
Health Risk |
Likely pathogenic |
— |
| RS575983927 |
SOS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Noonan syndrome 9, Cardiovascular phenotype |
| RS57599352 |
KRT5
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex, Epidermolysis bullosa simplex 2B |
| RS575999145 |
TF
|
Health Risk |
Conflicting classifications of pathogenicity |
Atransferrinemia, TF-related disorder |
| RS576001667 |
PKHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive polycystic kidney disease, Polycystic kidney disease 4 |
| RS576025689 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS576030298 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Aortic valve disease 1 |
| RS576035669 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS576041742 |
RAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, RASopathy |
| RS576051028 |
ANKH
|
Health Risk |
Conflicting classifications of pathogenicity |
Chondrocalcinosis 2, Craniometaphyseal dysplasia |
| RS576055272 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome 4 |
| RS576057388 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 42 |
| RS57605939 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial cancer of breast, Hereditary cancer-predisposing syndrome |
| RS576071932 |
GNAS
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant tumor of esophagus, Familial cancer of breast |
| RS576073679 |
MAGEL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, MAGEL2-related disorder |
| RS576076237 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS576076928 |
EVC
|
Health Risk |
Likely pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS576080629 |
MAP3K1
|
Health Risk |
Conflicting classifications of pathogenicity |
46, XY sex reversal 6 |
| RS576081828 |
PALB2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS576091247 |
BMPR2
|
Health Risk |
Pathogenic |
Pulmonary hypertension, primary |
| RS576096758 |
DNAH5
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 3, Primary ciliary dyskinesia |
| RS576099495 |
CACNA1A
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 42 |
| RS576108168 |
DOCK6
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS576108341 |
LAMB2
|
Health Risk |
Conflicting classifications of pathogenicity |
LAMB2-related disorder, Pierson syndrome |
| RS576118131 |
ADCY10
|
Health Risk |
Pathogenic |
— |
| RS576125279 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Long QT syndrome 2 |
| RS576127046 |
STX1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Generalized epilepsy with febrile seizures plus, type 9 |
| RS576130413 |
DYSF
|
Health Risk |
Pathogenic |
Miyoshi muscular dystrophy 1, Autosomal recessive limb-girdle muscular dystrophy type 2B |
| RS576139929 |
ASPM
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly 5, primary |
| RS576141199 |
CACNA1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Episodic ataxia type 2, Developmental and epileptic encephalopathy |
| RS576156828 |
KCNJ5
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiovascular phenotype |
| RS576163042 |
ANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS576171217 |
LIPT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS576172127 |
COL18A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS576175174 |
CBL
|
Health Risk |
Conflicting classifications of pathogenicity |
RASopathy, Cardiovascular phenotype |
| RS576176888 |
BAP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, BAP1-related tumor predisposition syndrome |
| RS576180572 |
TUBB3
|
Health Risk |
Conflicting classifications of pathogenicity |
TUBB3-related disorder, TUBB3-related disorder |
| RS576187743 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic osteodysplastic primordial dwarfism type II, PCNT-related disorder |
| RS576190086 |
CDH3
|
Health Risk |
Conflicting classifications of pathogenicity |
EEM syndrome, EEM syndrome |
| RS576193460 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS576198476 |
DCTN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Perry syndrome, Amyotrophic lateral sclerosis type 1 |
| RS576204286 |
MSH3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, MSH3-related disorder |
| RS576215366 |
DOK7
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital myasthenic syndrome 10, Fetal akinesia deformation sequence 1 |
| RS576221121 |
AARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease axonal type 2N |
| RS576233044 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS576239597 |
MKS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Meckel-Gruber syndrome, Joubert syndrome |
| RS576243101 |
PROKR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism 3 with or without anosmia, Hypogonadotropic hypogonadism 3 with or without anosmia |
| RS576247658 |
BMPR1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Juvenile polyposis syndrome |
| RS576252504 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex 5B, with muscular dystrophy |
| RS576269342 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome 5 |
| RS576271894 |
VCL
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1W, Cardiovascular phenotype |
| RS576279166 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS576282835 |
NLRC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Periodic fever-infantile enterocolitis-autoinflammatory syndrome, Familial cold autoinflammatory syndrome 4 |
| RS576284122 |
IHH
|
Health Risk |
Conflicting classifications of pathogenicity |
Brachydactyly type A1, Inborn genetic diseases |
| RS576284630 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 6, WFS1-Related Spectrum Disorders |
| RS576293240 |
POLQ
|
Health Risk |
Conflicting classifications of pathogenicity |
POLQ-related disorder, POLQ-related disorder |
| RS57629361 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 2, autosomal dominant |
| RS576298659 |
CC2D2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 9, Meckel-Gruber syndrome |
| RS57629991 |
KRT6A
|
Health Risk |
Pathogenic/Likely pathogenic |
— |
| RS576300014 |
VSX1
|
Health Risk |
Conflicting classifications of pathogenicity |
Posterior polymorphous corneal dystrophy, Craniofacial anomalies and anterior segment dysgenesis syndrome |
| RS576303132 |
MSH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Lynch syndrome 1 |
| RS576303662 |
CPS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital hyperammonemia, type I |
| RS576304398 |
TMEM80
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS576315457 |
CTNS
|
Health Risk |
Conflicting classifications of pathogenicity |
Ocular cystinosis, Juvenile nephropathic cystinosis |
| RS576320358 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS576323709 |
APOB
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypercholesterolemia, autosomal dominant |
| RS576324046 |
HSPG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Lethal Kniest-like syndrome, Schwartz-Jampel syndrome |
| RS576330538 |
RPL5
|
Health Risk |
Conflicting classifications of pathogenicity |
Diamond-Blackfan anemia 6, Diamond-Blackfan anemia |
| RS576332528 |
COL5A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS576340695 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary hyperinsulinism, Maturity-onset diabetes of the young |
| RS576359448 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS576369528 |
PLEC
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex 5B, with muscular dystrophy |
| RS576373730 |
RBP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinal dystrophy, Retinal dystrophy |
| RS576374797 |
IL12RB1
|
Health Risk |
Pathogenic |
Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency, Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency |
| RS576383569 |
CARD11
|
Health Risk |
Conflicting classifications of pathogenicity |
BENTA disease, Severe combined immunodeficiency due to CARD11 deficiency |
| RS576395584 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Marfan syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS576399072 |
MYO15A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive nonsyndromic hearing loss 3, Autosomal recessive nonsyndromic hearing loss 3 |
| RS576399709 |
PEX6
|
Health Risk |
Conflicting classifications of pathogenicity |
Peroxisome biogenesis disorder, PEX6-related disorder |
| RS57639980 |
DES
|
Health Risk |
Pathogenic/Likely pathogenic |
Desmin-related myofibrillar myopathy, Desmin-related myofibrillar myopathy |
| RS576401026 |
OTOF
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS576401425 |
ZNF469
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, Cardiovascular phenotype |
| RS576404380 |
DSG2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Arrhythmogenic right ventricular dysplasia 10 |
| RS576411922 |
RAB3GAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Martsolf syndrome, Warburg micro syndrome 2 |
| RS576429729 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS576430165 |
NDUFAF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial complex I deficiency, nuclear type 1 |
| RS576431612 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS576434469 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Adams-Oliver syndrome 5, Adams-Oliver syndrome 5 |
| RS576445739 |
CHST6
|
Health Risk |
Conflicting classifications of pathogenicity |
Macular corneal dystrophy, Macular corneal dystrophy |