SNP Directory

1,898 genetic variants in our database.

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All (1,898) Health Risk (400,964) Other (47,777) Drug Response (1,898) Trait (128) Protective (50)
RSID Gene Category Clinical Significance Conditions
RS552928147 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS554056486 COMT Drug Response drug response Tramadol response, Tramadol response
RS55640102 CYP2C19 Drug Response drug response CYP2C19: uncertain function, CYP2C19: uncertain function
RS55752064 CYP2C19 Drug Response drug response CYP2C19: uncertain function, CYP2C19: uncertain function
RS557690438 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS55886062 DPYD Drug Response drug response Dihydropyrimidine dehydrogenase deficiency, fluorouracil response - Other
RS56005131 DPYD Drug Response drug response Dihydropyrimidine dehydrogenase deficiency, fluorouracil response - Other
RS56019966 TPMT Drug Response Likely benign; drug response Azathioprine response, TPMT-related disorder
RS56038477 DPYD Drug Response drug response Dihydropyrimidine dehydrogenase deficiency, capecitabine response - Toxicity
RS561496509 CYP2D6 Drug Response drug response Tramadol response, Tramadol response
RS561536243 COMT Drug Response drug response Tramadol response, Tramadol response
RS56161402 TPMT Drug Response drug response Thiopurine S-methyltransferase deficiency, Thiopurine S-methyltransferase deficiency
RS562436480 CYP2D6 Drug Response drug response Tramadol response, Tramadol response
RS562859 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS563256432 UGT2B7 Drug Response drug response Tramadol response, Tramadol response
RS56337013 CYP2C19 Drug Response drug response MEPHENYTOIN, POOR METABOLISM OF
RS563649 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS565311765 ABCB1 Drug Response drug response Tramadol response, Tramadol response
RS566654614 ABCB1 Drug Response drug response Tramadol response, Tramadol response
RS567300902 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS570852533 COMT Drug Response drug response Tramadol response, Tramadol response
RS571184450 ABCB1 Drug Response drug response Tramadol response, Tramadol response
RS571470402 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS573146761 CYP2D6 Drug Response drug response Tramadol response, Tramadol response
RS573698787 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS577345039 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS57913007 UGT2B7 Drug Response drug response Tramadol response, Tramadol response
RS58898486 ABCB1 Drug Response drug response Tramadol response, Tramadol response
RS58973490 CYP2C19 Drug Response drug response CYP2C19: normal function, CYP2C19: normal function
RS59086055 DPYD Drug Response drug response Dihydropyrimidine dehydrogenase deficiency, fluorouracil response - Other
RS59439148 ALOX5 Drug Response drug response; risk factor Atherosclerosis, susceptibility to
RS60254893 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS60529914 UGT2B7 Drug Response drug response Tramadol response, Tramadol response
RS606545 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS61040122 ABCB1 Drug Response drug response Tramadol response, Tramadol response
RS61122623 ABCB1 Drug Response drug response Tramadol response, Tramadol response
RS61737946 CYP2D6 Drug Response drug response Tramadol response, Tramadol response
RS61742245 VKORC1 Drug Response drug response Warfarin response, Vitamin K-dependent clotting factors
RS623956 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS6413438 CYP2C19 Drug Response drug response CYP2C19: decreased function, CYP2C19: decreased function
RS650245 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS650825 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS671 ALDH2 Drug Response drug response Alcohol sensitivity, acute
RS67376798 DPYD Drug Response drug response Dihydropyrimidine dehydrogenase deficiency, Fluorouracil response
RS675026 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS6851533 UGT2B7 Drug Response drug response Tramadol response, Tramadol response
RS6912029 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS71021021 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS713598 TAS2R38 Drug Response drug response Phenylthiocarbamide tasting, Phenylthiocarbamide tasting
RS71647871 CES1 Drug Response drug response clopidogrel response - Efficacy, clopidogrel response - Metabolism/PK
RS72549303 DPYD Drug Response drug response fluorouracil response - Other, Dihydropyrimidine dehydrogenase deficiency
RS72549306 DPYD Drug Response drug response fluorouracil response - Other, fluorouracil response - Other
RS72552267 CYP2C19 Drug Response drug response CYP2C19: no function, CYP2C19: no function
RS72558186 CYP2C19 Drug Response drug response CYP2C19: no function, CYP2C19: no function
RS7270101 ITPA Drug Response drug response Inosine triphosphatase deficiency, peginterferon alfa-2b and ribavirin response - Toxicity
RS727479 CYP19A1 Drug Response drug response Letrozole response, Letrozole response
RS727503013 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727503014 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727503015 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727503016 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727503019 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727503020 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727503021 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504232 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504256 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504257 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504258 EGFR Drug Response Likely pathogenic; drug response Tyrosine kinase inhibitor response, Lung adenocarcinoma
RS727504263 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Diffuse midline glioma
RS727504266 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504278 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Lung adenocarcinoma
RS727504281 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504282 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504316 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504324 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504326 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504332 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504339 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504395 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504402 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504414 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504428 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS727504444 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS7294 VKORC1 Drug Response drug response warfarin response - Dosage, Vitamin K-dependent clotting factors
RS730880333 EGFR Drug Response drug response Tyrosine kinase inhibitor response, Tyrosine kinase inhibitor response
RS730882170 CYP2D6 Drug Response drug response —
RS730882251 CYP2D6 Drug Response drug response —
RS73823859 UGT2B7 Drug Response drug response Tramadol response, Tramadol response
RS73823860 UGT2B7 Drug Response drug response Tramadol response, Tramadol response
RS7412 APOE Drug Response drug response Familial type 3 hyperlipoproteinemia, atorvastatin response - Efficacy
RS7438244 UGT2B7 Drug Response drug response Tramadol response, Tramadol response
RS7439326 UGT2B7 Drug Response drug response Tramadol response, Tramadol response
RS7439366 UGT2B7 Drug Response drug response Tramadol response, Tramadol response
RS74423290 TPMT Drug Response drug response Thiopurine S-methyltransferase deficiency, Thiopurine S-methyltransferase deficiency
RS74503330 CFTR Drug Response Pathogenic; drug response Cystic fibrosis, ivacaftor response - Efficacy
RS745638449 UGT2B7 Drug Response drug response Tramadol response, Tramadol response
RS745863104 OPRM1 Drug Response drug response Tramadol response, Tramadol response
RS746071566 NUDT15 Drug Response Likely benign; drug response Thiopurines, poor metabolism of
RS746205498 ABCB1 Drug Response drug response Tramadol response, Tramadol response
RS746946995 ABCB1 Drug Response drug response Tramadol response, Tramadol response
RS747345350 OPRM1 Drug Response drug response Tramadol response, Tramadol response
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