RS713598 TAS2R38

Drug Response Chr 7:141973544 snv missense variant

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What This Variant Does

"rs713598 is one of three SNPs that form the main haplotypes behind the ability to perceive as bitter...

Associated Conditions

Phenylthiocarbamide tasting

GWAS Studies (7)

Trait	Risk Allele	OR / Beta	P-value	Study
Bitter taste response	—	—	2E-104	PubMed
Horseradish liking	G	β: 0.041	5E-29	PubMed
Drinks per week	G	β: 0.008	5E-22	PubMed
Drinks per week	G	β: 0.009	1E-20	PubMed
Tea consumption	G	β: 0.01	3E-10	PubMed
Alcohol liking	G	β: 0.077	1E-9	PubMed
Whiskey liking	G	β: 0.022	1E-9	PubMed

Population Frequencies

gnomAD ALL

1kG AFR

47.5%

1kG ALL

50.5%

1kG AMR

34.1%

1kG EAS

32.4%

1kG EUR

57.8%

1kG SAS

65.5%

Other Variants in TAS2R38