| RS762855622 |
WRN
|
Health Risk |
Likely pathogenic |
Werner syndrome, Werner syndrome |
| RS762857737 |
PHIP
|
Health Risk |
Likely pathogenic |
PHIP-related behavioral problems-intellectual disability-obesity-dysmorphic features syndrome, PHIP-related behavioral problems-intellectual disability-obesity-dysmorphic features syndrome |
| RS762858023 |
TNC
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762859509 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS762859894 |
ACAD9
|
Health Risk |
Pathogenic |
— |
| RS762859925 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS762860653 |
DMD
|
Health Risk |
Pathogenic |
Duchenne muscular dystrophy, Duchenne muscular dystrophy |
| RS762861196 |
LAMA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Junctional epidermolysis bullosa gravis of Herlitz, Laryngo-onycho-cutaneous syndrome |
| RS762863150 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic osteodysplastic primordial dwarfism type II, Microcephalic osteodysplastic primordial dwarfism type II |
| RS762863861 |
MET
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal cell carcinoma, Hereditary cancer-predisposing syndrome |
| RS762864856 |
GLRA1
|
Health Risk |
Pathogenic |
Hyperekplexia 1, Hyperekplexia 1 |
| RS76286489 |
TGM6
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762865001 |
NEU1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762865950 |
IFIH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Aicardi-Goutieres syndrome 7, Singleton-Merten syndrome 1 |
| RS762866205 |
ARHGAP24
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762866453 |
ATP7B
|
Health Risk |
Pathogenic/Likely pathogenic |
Wilson disease, Wilson disease |
| RS762867111 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Bethlem myopathy 1A, COL6A1-related disorder |
| RS762867923 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS762868036 |
CSPP1
|
Health Risk |
Pathogenic |
Joubert syndrome 21, Joubert syndrome 21 |
| RS762868199 |
AHNAK2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762869685 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2A, Retinal dystrophy |
| RS762870190 |
NSD2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762871408 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762871779 |
SRP54
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762871906 |
TOPORS
|
Health Risk |
Conflicting classifications of pathogenicity |
Retinitis pigmentosa, Retinal dystrophy |
| RS762873423 |
TRNT1
|
Health Risk |
Pathogenic |
Congenital sideroblastic anemia-B-cell immunodeficiency-periodic fever-developmental delay syndrome, Congenital sideroblastic anemia-B-cell immunodeficiency-periodic fever-developmental delay syndrome |
| RS762873425 |
ZNF225
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762873672 |
CYP2U1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary spastic paraplegia 56, Spastic paraplegia |
| RS762873763 |
DYNC2H1
|
Health Risk |
Pathogenic |
Asphyxiating thoracic dystrophy 3, Jeune thoracic dystrophy |
| RS762873839 |
CLN5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronal ceroid lipofuscinosis, Neuronal ceroid lipofuscinosis 5 |
| RS762874007 |
ANO5
|
Health Risk |
Pathogenic/Likely pathogenic |
Gnathodiaphyseal dysplasia, Autosomal recessive limb-girdle muscular dystrophy type 2L |
| RS762874073 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS762874609 |
PIEZO2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762875633 |
TCF20
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762875734 |
CHRND
|
Health Risk |
Pathogenic/Likely pathogenic |
Lethal multiple pterygium syndrome, Congenital myasthenic syndrome 3C |
| RS762876022 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS762876355 |
ABCB7
|
Health Risk |
Likely pathogenic |
X-linked sideroblastic anemia with ataxia, Nonpapillary renal cell carcinoma |
| RS762876554 |
LHFPL5
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 67, Hearing loss |
| RS762876815 |
KDM6B
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities, Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities |
| RS762877422 |
DSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 11, Cardiomyopathy |
| RS762879329 |
SLC18A2
|
Health Risk |
Likely pathogenic |
Abnormal brain morphology, Abnormal brain morphology |
| RS762879569 |
PANK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Pigmentary pallidal degeneration, Pigmentary pallidal degeneration |
| RS762879895 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Cardiovascular phenotype |
| RS762881892 |
NEB
|
Health Risk |
Pathogenic/Likely pathogenic |
Arthrogryposis multiplex congenita 6, Nemaline myopathy 2 |
| RS762881899 |
DONSON
|
Health Risk |
Likely pathogenic |
— |
| RS762884881 |
NEBL
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Primary dilated cardiomyopathy |
| RS762885128 |
PIGO
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperphosphatasia with intellectual disability syndrome 2, Inborn genetic diseases |
| RS762885546 |
ECHS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Mitochondrial short-chain Enoyl-Coa hydratase 1 deficiency, Mitochondrial short-chain Enoyl-Coa hydratase 1 deficiency |
| RS762885804 |
ERCC4
|
Health Risk |
Conflicting classifications of pathogenicity |
Xeroderma pigmentosum, group F |
| RS762885961 |
TTC21B
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Nephronophthisis |
| RS762886975 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Fanconi anemia complementation group D1 |
| RS762887399 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia, Beauce type |
| RS762887805 |
CLCN2
|
Health Risk |
Likely pathogenic |
Leukoencephalopathy with mild cerebellar ataxia and white matter edema, Leukoencephalopathy with mild cerebellar ataxia and white matter edema |
| RS762887911 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS762888022 |
CFTR
|
Health Risk |
Conflicting classifications of pathogenicity |
Cystic fibrosis, CFTR-related disorder |
| RS762889441 |
SMAD3
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Ehlers-Danlos syndrome |
| RS762889850 |
LZTR1
|
Health Risk |
Pathogenic |
Hereditary cancer-predisposing syndrome, Cardiovascular phenotype |
| RS762890510 |
SETBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, See cases |
| RS762890562 |
DDX41
|
Health Risk |
Pathogenic/Likely pathogenic |
Acute myeloid leukemia, DDX41-related hematologic malignancy predisposition syndrome |
| RS762891322 |
CHD7
|
Health Risk |
Conflicting classifications of pathogenicity |
CHARGE syndrome, Inborn genetic diseases |
| RS762891600 |
NRXN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Pitt-Hopkins-like syndrome 2, Pitt-Hopkins-like syndrome 2 |
| RS762892362 |
HEXB
|
Health Risk |
Pathogenic/Likely pathogenic |
Sandhoff disease, Sandhoff disease |
| RS762894736 |
PTS
|
Health Risk |
Conflicting classifications of pathogenicity |
6-Pyruvoyl-tetrahydrobiopterin synthase deficiency, Inborn genetic diseases |
| RS762896797 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Spastic paraplegia |
| RS762896810 |
CACNA1C
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Brugada syndrome 3 |
| RS762898113 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary cancer-predisposing syndrome |
| RS762898505 |
FOXP1
|
Health Risk |
Conflicting classifications of pathogenicity |
FOXP1-related disorder, FOXP1-related disorder |
| RS762899641 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS762900005 |
BMPR1A
|
Health Risk |
Pathogenic |
Juvenile polyposis syndrome, Juvenile polyposis syndrome |
| RS762900727 |
COQ8A
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive ataxia due to ubiquinone deficiency, Autosomal recessive ataxia due to ubiquinone deficiency |
| RS762900875 |
FLG2
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762900894 |
NPHS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Kidney disorder, Kidney disorder |
| RS762901763 |
MTTP
|
Health Risk |
Pathogenic |
Abetalipoproteinaemia, MTTP-related disorder |
| RS762902309 |
FANCA
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group A, Fanconi anemia |
| RS762902447 |
SPTB
|
Health Risk |
Likely pathogenic |
Hereditary spherocytosis type 2, Hereditary spherocytosis type 2 |
| RS762902803 |
PDSS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Deafness-encephaloneuropathy-obesity-valvulopathy syndrome, Deafness-encephaloneuropathy-obesity-valvulopathy syndrome |
| RS762902907 |
CLN6
|
Health Risk |
Pathogenic/Likely pathogenic |
Ceroid lipofuscinosis, neuronal |
| RS762903007 |
IDUA
|
Health Risk |
Pathogenic |
Hurler syndrome, Mucopolysaccharidosis type 1 |
| RS76290319 |
SMCHD1
|
Health Risk |
Conflicting classifications of pathogenicity |
Facioscapulohumeral muscular dystrophy 2, Inborn genetic diseases |
| RS762903420 |
TONSL
|
Health Risk |
Pathogenic |
Sponastrime dysplasia, Sponastrime dysplasia |
| RS762904815 |
BRPF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Intellectual developmental disorder with dysmorphic facies and ptosis |
| RS762905130 |
FAM20A
|
Health Risk |
Likely pathogenic |
Amelogenesis imperfecta type 1G, Amelogenesis imperfecta type 1G |
| RS762905152 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Tibial muscular dystrophy, Myopathy |
| RS762905211 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Arrhythmogenic right ventricular dysplasia 2 |
| RS762905862 |
KIAA0586
|
Health Risk |
Likely pathogenic |
Joubert syndrome 23, Joubert syndrome 23 |
| RS762905941 |
TRIM32
|
Health Risk |
Conflicting classifications of pathogenicity |
Sarcotubular myopathy, Bardet-Biedl syndrome |
| RS762908108 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Hereditary breast ovarian cancer syndrome |
| RS762908120 |
SH3PXD2B
|
Health Risk |
Conflicting classifications of pathogenicity |
Frank-Ter Haar syndrome, Frank-Ter Haar syndrome |
| RS762908677 |
NGLY1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital disorder of deglycosylation, Congenital disorder of deglycosylation |
| RS762909195 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762909359 |
DOCK2
|
Health Risk |
Pathogenic |
DOCK2 deficiency, DOCK2 deficiency |
| RS762909447 |
ABCA4
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS762910638 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Early-infantile DEE |
| RS76291085 |
NLRP3
|
Health Risk |
Conflicting classifications of pathogenicity |
Cryopyrin associated periodic syndrome, Cryopyrin associated periodic syndrome |
| RS762910963 |
OTC
|
Health Risk |
Conflicting classifications of pathogenicity |
Ornithine carbamoyltransferase deficiency, Inborn genetic diseases |
| RS762911032 |
COL2A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762911981 |
PKD1
|
Health Risk |
Pathogenic |
Polycystic kidney disease, adult type |
| RS762913101 |
MECR
|
Health Risk |
Pathogenic/Likely pathogenic |
Dystonia, childhood-onset |
| RS762913325 |
SGMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS762913390 |
LARS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Malignant tumor of urinary bladder, Malignant tumor of urinary bladder |