| RS754338217 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Retinitis pigmentosa 80 |
| RS754338522 |
FIG4
|
Health Risk |
Likely pathogenic |
Charcot-Marie-Tooth disease type 4, Charcot-Marie-Tooth disease type 4 |
| RS754341326 |
COL7A1
|
Health Risk |
Conflicting classifications of pathogenicity |
See cases, Inborn genetic diseases |
| RS754341393 |
BRAT1
|
Health Risk |
Pathogenic |
Neonatal-onset encephalopathy with rigidity and seizures, Neonatal-onset encephalopathy with rigidity and seizures |
| RS754341838 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Inborn genetic diseases |
| RS754342536 |
THBD
|
Health Risk |
Conflicting classifications of pathogenicity |
Thrombomodulin-related bleeding disorder, Atypical hemolytic-uremic syndrome with thrombomodulin anomaly |
| RS754342872 |
VIPAS39
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754343113 |
SYNE4
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 76, Autosomal recessive nonsyndromic hearing loss 76 |
| RS754343186 |
TSC2
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis 2, Hereditary cancer-predisposing syndrome |
| RS754343223 |
NF1
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurofibromatosis, type 1 |
| RS754343759 |
NME8
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia 6 |
| RS754345067 |
EIF2AK3
|
Health Risk |
Pathogenic |
— |
| RS754346307 |
ADGRV1
|
Health Risk |
Conflicting classifications of pathogenicity |
Febrile seizures, familial |
| RS754346893 |
WFS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 6, WFS1-Related Spectrum Disorders |
| RS754347572 |
DMD
|
Health Risk |
Conflicting classifications of pathogenicity |
Duchenne muscular dystrophy, Cardiovascular phenotype |
| RS75434768 |
ALK
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuroblastoma, susceptibility to |
| RS754348627 |
KAT6B
|
Health Risk |
Likely pathogenic |
Blepharophimosis - intellectual disability syndrome, SBBYS type |
| RS754348681 |
SETX
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Amyotrophic lateral sclerosis type 4 |
| RS754348901 |
ELP1
|
Health Risk |
Likely pathogenic |
Familial dysautonomia, Familial dysautonomia |
| RS754349088 |
PYCR2
|
Health Risk |
Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS754349366 |
PYCR1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754349925 |
STXBP1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754350357 |
CLCN1
|
Health Risk |
Likely pathogenic |
Congenital myotonia, autosomal dominant form |
| RS754350384 |
SELENON
|
Health Risk |
Conflicting classifications of pathogenicity |
SEPN1-related disorder, Eichsfeld type congenital muscular dystrophy |
| RS754350576 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS754351705 |
VPS16
|
Health Risk |
Conflicting classifications of pathogenicity |
Dystonia 30, Dystonia 30 |
| RS754351718 |
FBN1
|
Health Risk |
Pathogenic |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS754352569 |
NBN
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephaly, normal intelligence and immunodeficiency |
| RS754353693 |
CERKL
|
Health Risk |
Pathogenic |
— |
| RS754354190 |
DSP
|
Health Risk |
Pathogenic/Likely pathogenic |
Cardiovascular phenotype, Cardiomyopathy |
| RS754354210 |
MYH9
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 17, Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss |
| RS754354488 |
NEB
|
Health Risk |
Conflicting classifications of pathogenicity |
Nemaline myopathy 2, Nemaline myopathy 2 |
| RS754354560 |
RB1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Retinoblastoma |
| RS754355185 |
ZNF143
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754355745 |
SYNE1
|
Health Risk |
Conflicting classifications of pathogenicity |
Emery-Dreifuss muscular dystrophy 4, autosomal dominant |
| RS754356257 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2J, Dilated cardiomyopathy 1G |
| RS754357121 |
MMAB
|
Health Risk |
Conflicting classifications of pathogenicity |
Methylmalonic aciduria, cblB type |
| RS754357906 |
USP9X
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental delay, Developmental delay |
| RS754358467 |
ABCA12
|
Health Risk |
Pathogenic |
— |
| RS754358716 |
GPR179
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754358942 |
SLC26A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Hypersulfaturia |
| RS754359147 |
TERT
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, Idiopathic Pulmonary Fibrosis |
| RS754359356 |
ACADM
|
Health Risk |
Conflicting classifications of pathogenicity |
Medium-chain acyl-coenzyme A dehydrogenase deficiency, Medium-chain acyl-coenzyme A dehydrogenase deficiency |
| RS754360853 |
FLNB
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754361205 |
LAMA1
|
Health Risk |
Pathogenic |
— |
| RS754363068 |
CPT2
|
Health Risk |
Pathogenic/Likely pathogenic |
Carnitine palmitoyl transferase II deficiency, myopathic form |
| RS754363694 |
APC
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 1 |
| RS754364233 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS754364718 |
MUTYH
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial adenomatous polyposis 2 |
| RS754364756 |
AHDC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS754365572 |
POU4F1
|
Health Risk |
Conflicting classifications of pathogenicity |
POU4F1-related disorder, POU4F1-related disorder |
| RS754365623 |
CD36
|
Health Risk |
Conflicting classifications of pathogenicity |
Platelet-type bleeding disorder 10, CD36-related disorder |
| RS754366579 |
CDKN2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial melanoma |
| RS754367349 |
RAD51C
|
Health Risk |
Pathogenic/Likely pathogenic |
Fanconi anemia complementation group O, Breast-ovarian cancer |
| RS754368658 |
PARN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dyskeratosis congenita, autosomal recessive 6 |
| RS754368714 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
TTN-related disorder, TTN-related disorder |
| RS754369323 |
MMUT
|
Health Risk |
Pathogenic |
Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency, Methylmalonic aciduria due to complete methylmalonyl-CoA mutase deficiency |
| RS754369875 |
NEB
|
Health Risk |
Pathogenic |
Nemaline myopathy 2, Arthrogryposis multiplex congenita 6 |
| RS754369980 |
SETD1A
|
Health Risk |
Conflicting classifications of pathogenicity |
Neurodevelopmental disorder with speech impairment and dysmorphic facies, Neurodevelopmental disorder with speech impairment and dysmorphic facies |
| RS754370015 |
NFATC1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754370463 |
TMEM67
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome, Meckel-Gruber syndrome |
| RS754370770 |
ANKRD11
|
Health Risk |
Conflicting classifications of pathogenicity |
KBG syndrome, KBG syndrome |
| RS754371531 |
UNC80
|
Health Risk |
Pathogenic |
— |
| RS754371834 |
LIFR
|
Health Risk |
Conflicting classifications of pathogenicity |
Stuve-Wiedemann syndrome, Stuve-Wiedemann syndrome |
| RS754372754 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Marfan syndrome |
| RS754373136 |
ACTN2
|
Health Risk |
Conflicting classifications of pathogenicity |
Myopathy, congenital |
| RS754373273 |
SEPSECS
|
Health Risk |
Likely pathogenic |
Pontocerebellar hypoplasia type 2D, Pontocerebellar hypoplasia type 2D |
| RS754373473 |
WFS1
|
Health Risk |
Likely pathogenic |
— |
| RS754373519 |
IFT140
|
Health Risk |
Conflicting classifications of pathogenicity |
Saldino-Mainzer syndrome, Retinitis pigmentosa 80 |
| RS754374132 |
USH2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Usher syndrome type 2A, Retinitis pigmentosa 39 |
| RS754374362 |
NOTCH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, Adams-Oliver syndrome 5 |
| RS754374567 |
DOCK8
|
Health Risk |
Conflicting classifications of pathogenicity |
Combined immunodeficiency due to DOCK8 deficiency, Combined immunodeficiency due to DOCK8 deficiency |
| RS754375124 |
CAPN3
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2A, Autosomal recessive limb-girdle muscular dystrophy type 2A |
| RS754378340 |
SLC12A3
|
Health Risk |
Pathogenic |
Familial hypokalemia-hypomagnesemia, Inborn genetic diseases |
| RS754378464 |
GCDH
|
Health Risk |
Pathogenic |
Glutaric aciduria, type 1 |
| RS754378887 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS754379238 |
RAI1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS754379411 |
NGLY1
|
Health Risk |
Pathogenic |
Congenital disorder of deglycosylation, Inborn genetic diseases |
| RS754379518 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS754379725 |
THOC6
|
Health Risk |
Likely pathogenic |
THOC6-related developmental delay-microcephaly-facial dysmorphism syndrome, THOC6-related developmental delay-microcephaly-facial dysmorphism syndrome |
| RS754380009 |
CACNB4
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, CACNB4-related disorder |
| RS754380060 |
EHMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Kleefstra syndrome 1, Inborn genetic diseases |
| RS754381972 |
SACS
|
Health Risk |
Conflicting classifications of pathogenicity |
Charlevoix-Saguenay spastic ataxia, Inborn genetic diseases |
| RS754383840 |
FOXRED1
|
Health Risk |
Pathogenic |
— |
| RS754383898 |
KCNT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 14 |
| RS754384143 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1G, Autosomal recessive limb-girdle muscular dystrophy type 2J |
| RS754384963 |
COL6A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Collagen 6-related myopathy, Bethlem myopathy 1A |
| RS754385182 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia, Primary ciliary dyskinesia |
| RS754385274 |
ARMC9
|
Health Risk |
Pathogenic |
Joubert syndrome 30, Joubert syndrome 30 |
| RS754385929 |
NOTCH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hajdu-Cheney syndrome, NOTCH2-related disorder |
| RS754386072 |
CREBBP
|
Health Risk |
Conflicting classifications of pathogenicity |
Menke-Hennekam syndrome 1, Rubinstein-Taybi syndrome due to CREBBP mutations |
| RS754386565 |
CPT2
|
Health Risk |
Pathogenic/Likely pathogenic |
Carnitine palmitoyl transferase II deficiency, neonatal form |
| RS754386652 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 4, Cardiovascular phenotype |
| RS754387675 |
PDE10A
|
Health Risk |
Conflicting classifications of pathogenicity |
PDE10A-related disorder, PDE10A-related disorder |
| RS754388460 |
MYH7
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiomyopathy |
| RS754388534 |
CDH1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary diffuse gastric adenocarcinoma, Hereditary cancer-predisposing syndrome |
| RS754389345 |
COL5A2
|
Health Risk |
Conflicting classifications of pathogenicity |
Ehlers-Danlos syndrome, classic type |
| RS754389465 |
TWNK
|
Health Risk |
Conflicting classifications of pathogenicity |
Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 3 |
| RS754390284 |
RBBP8
|
Health Risk |
Pathogenic/Likely pathogenic |
Inborn genetic diseases, Inborn genetic diseases |
| RS754390440 |
ACTN4
|
Health Risk |
Conflicting classifications of pathogenicity |
Focal segmental glomerulosclerosis 1, Inborn genetic diseases |