| RS587784573 |
GUCY2C
|
Health Risk |
Pathogenic |
Meconium ileus, Meconium ileus |
| RS58789393 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Cardiovascular phenotype |
| RS58806616 |
ALMS1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alstrom syndrome, Monogenic diabetes |
| RS58820146 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperinsulinemic hypoglycemia, familial |
| RS58824091 |
TMC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nonsyndromic hearing loss 36, Autosomal recessive nonsyndromic hearing loss 7 |
| RS5882827 |
DNAH11
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary ciliary dyskinesia 7, DNAH11-related disorder |
| RS58835716 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS58850446 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Cardiovascular phenotype |
| RS58852768 |
KRT10
|
Health Risk |
Pathogenic |
Congenital reticular ichthyosiform erythroderma, Annular epidermolytic ichthyosis |
| RS5887 |
CETP
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS58896330 |
POMT1
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive limb-girdle muscular dystrophy type 2K, Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability) |
| RS58898021 |
DES
|
Health Risk |
Pathogenic |
Myofibrillar myopathy, Myofibrillar myopathy |
| RS58901407 |
KRT10
|
Health Risk |
Pathogenic |
Epidermolytic hyperkeratosis 2A, autosomal dominant |
| RS58907919 |
NEFL
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 1F, Charcot-Marie-Tooth disease type 2E |
| RS58912633 |
LMNA
|
Health Risk |
Pathogenic |
Congenital muscular dystrophy due to LMNA mutation, Congenital muscular dystrophy due to LMNA mutation |
| RS58916399 |
POLE
|
Health Risk |
Conflicting classifications of pathogenicity |
Colorectal cancer, susceptibility to |
| RS58917027 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Primary dilated cardiomyopathy, Inborn genetic diseases |
| RS58918655 |
KRT12
|
Health Risk |
Pathogenic |
Corneal dystrophy, Meesmann |
| RS58922911 |
LMNA
|
Health Risk |
Pathogenic |
Dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome, Dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome |
| RS58928370 |
KRT1
|
Health Risk |
Likely pathogenic |
Palmoplantar keratoderma, epidermolytic |
| RS58932704 |
LMNA
|
Health Risk |
Pathogenic/Likely pathogenic |
Emery-Dreifuss muscular dystrophy 2, autosomal dominant |
| RS58949162 |
KRT1
|
Health Risk |
Pathogenic |
— |
| RS58949384 |
MYH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 14, MYH6-related disorder |
| RS58978449 |
LMNA
|
Health Risk |
Pathogenic/Likely pathogenic |
Primary dilated cardiomyopathy, Charcot-Marie-Tooth disease type 2 |
| RS58982919 |
NEFL
|
Health Risk |
Pathogenic/Likely pathogenic |
Charcot-Marie-Tooth disease type 1F, Charcot-Marie-Tooth disease type 2E |
| RS5899 |
F2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital prothrombin deficiency, Thrombophilia due to thrombin defect |
| RS58999456 |
DES
|
Health Risk |
Pathogenic/Likely pathogenic |
Desmin-related myofibrillar myopathy, Primary familial dilated cardiomyopathy |
| RS5900 |
F2
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital prothrombin deficiency, Thrombophilia due to thrombin defect |
| RS5900078 |
COL27A1
|
Health Risk |
Pathogenic |
Steel syndrome, Steel syndrome |
| RS59004709 |
BRCA2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS59007872 |
FBN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial thoracic aortic aneurysm and aortic dissection, 8 conditions |
| RS5901000 |
TSC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Tuberous sclerosis syndrome, Tuberous sclerosis 1 |
| RS59022806 |
KRT1
|
Health Risk |
Pathogenic |
— |
| RS59026483 |
LMNA
|
Health Risk |
Pathogenic |
Dilated cardiomyopathy 1S, Charcot-Marie-Tooth disease type 2 |
| RS59027578 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS5903 |
PI4KA;SERPIND1
|
Health Risk |
Conflicting classifications of pathogenicity |
Heparin cofactor II deficiency, Heparin cofactor II deficiency |
| RS59040894 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS59056100 |
MSH6
|
Health Risk |
Conflicting classifications of pathogenicity |
Lynch syndrome 5, Breast and/or ovarian cancer |
| RS59062945 |
KDM6B
|
Health Risk |
Pathogenic |
Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities, Neurodevelopmental disorder with coarse facies and mild distal skeletal abnormalities |
| RS5906354 |
UBA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Infantile-onset X-linked spinal muscular atrophy, Inborn genetic diseases |
| RS59075499 |
KRT10
|
Health Risk |
Pathogenic |
Annular epidermolytic ichthyosis, Annular epidermolytic ichthyosis |
| RS59089201 |
KRT1
|
Health Risk |
Pathogenic |
Epidermolytic hyperkeratosis 1, Epidermolytic hyperkeratosis 1 |
| RS59092197 |
KRT5
|
Health Risk |
Pathogenic/Likely pathogenic |
Epidermolysis bullosa simplex with mottled pigmentation, Epidermolysis bullosa simplex with mottled pigmentation |
| RS59103647 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS59110575 |
KRT14
|
Health Risk |
Pathogenic |
— |
| RS59115483 |
KRT5
|
Health Risk |
Likely pathogenic |
Epidermolysis bullosa simplex, Epidermolysis bullosa simplex 2C |
| RS59117380 |
PLEKHG5
|
Health Risk |
Conflicting classifications of pathogenicity |
Neuronopathy, distal hereditary motor |
| RS59139861 |
USH2A
|
Health Risk |
Conflicting classifications of pathogenicity |
Usher syndrome type 2A, Retinitis pigmentosa |
| RS59148238 |
TTN
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Dilated cardiomyopathy 1G |
| RS59151464 |
KRT1
|
Health Risk |
Pathogenic |
Epidermolytic hyperkeratosis 1, Epidermolytic hyperkeratosis 1 |
| RS59151893 |
KRT17
|
Health Risk |
Pathogenic |
Pachyonychia congenita 2, Abnormality of the skin |
| RS59157279 |
ABCC6
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal recessive inherited pseudoxanthoma elasticum, Arterial calcification |
| RS59157477 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic osteodysplastic primordial dwarfism type II, PCNT-related disorder |
| RS59167148 |
EYA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1J, Autosomal dominant nonsyndromic hearing loss 10 |
| RS59169454 |
KRT1
|
Health Risk |
Pathogenic |
Ichthyosis hystrix of Curth-Macklin, Ichthyosis hystrix of Curth-Macklin |
| RS5917414 |
USP9X
|
Health Risk |
Conflicting classifications of pathogenicity |
Inborn genetic diseases, Inborn genetic diseases |
| RS59175042 |
KRT10
|
Health Risk |
Pathogenic |
— |
| RS5918118 |
USP9X
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual disability, X-linked 99 |
| RS59183158 |
PCNT
|
Health Risk |
Conflicting classifications of pathogenicity |
Microcephalic osteodysplastic primordial dwarfism type II, PCNT-related disorder |
| RS59184265 |
KRT5
|
Health Risk |
Conflicting classifications of pathogenicity |
Epidermolysis bullosa simplex, Epidermolysis bullosa simplex |
| RS59190330 |
RAB3GAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Martsolf syndrome, Warburg micro syndrome 2 |
| RS59190510 |
KRT5
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex 2A, generalized severe |
| RS5922 |
LCAT
|
Health Risk |
Conflicting classifications of pathogenicity |
LCAT deficiency, Cardiovascular phenotype |
| RS59243757 |
KRT5
|
Health Risk |
Pathogenic/Likely pathogenic |
Epidermolysis bullosa simplex, Epidermolysis bullosa simplex |
| RS59270054 |
LMNA
|
Health Risk |
Pathogenic |
Primary dilated cardiomyopathy, Charcot-Marie-Tooth disease type 2 |
| RS59285727 |
GFAP
|
Health Risk |
Pathogenic |
Alexander disease, Alexander disease |
| RS59296273 |
KRT9
|
Health Risk |
Pathogenic |
Epidermolytic palmoplantar keratoderma, 1 |
| RS59301204 |
LMNA
|
Health Risk |
Likely pathogenic |
Primary dilated cardiomyopathy, Cardiomyopathy |
| RS59308628 |
DES
|
Health Risk |
Pathogenic |
Desmin-related myofibrillar myopathy, Desmin-related myofibrillar myopathy |
| RS59328451 |
KRT16
|
Health Risk |
Conflicting classifications of pathogenicity |
Pachyonychia congenita 1, Pachyonychia congenita 1 |
| RS59331340 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiomyopathy, Catecholaminergic polymorphic ventricular tachycardia 1 |
| RS59332535 |
LMNA
|
Health Risk |
Pathogenic/Likely pathogenic |
Emery-Dreifuss muscular dystrophy 2, autosomal dominant |
| RS59349773 |
KRT16
|
Health Risk |
Likely pathogenic |
Pachyonychia congenita 1, Pachyonychia congenita 1 |
| RS59355923 |
CACNA1F
|
Health Risk |
Conflicting classifications of pathogenicity |
CACNA1F-related disorder, CACNA1F-related disorder |
| RS59362219 |
GALNT12
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast neoplasm, GALNT12-related disorder |
| RS59375065 |
KRT14
|
Health Risk |
Likely pathogenic |
— |
| RS59429455 |
KRT1
|
Health Risk |
Likely pathogenic |
Epidermolytic ichthyosis, KRT1-related disorder |
| RS59431308 |
ACTC1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypertrophic cardiomyopathy 11, Dilated cardiomyopathy 1R |
| RS59442925 |
KRT14
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex, Epidermolysis bullosa simplex |
| RS59443548 |
CYP27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cholestanol storage disease, Cholestanol storage disease |
| RS59443585 |
NEFL
|
Health Risk |
Pathogenic |
Charcot-Marie-Tooth disease type 2E, Charcot-Marie-Tooth disease type 2E |
| RS59446030 |
PIEZO1
|
Health Risk |
Conflicting classifications of pathogenicity |
Dehydrated hereditary stomatocytosis with or without pseudohyperkalemia and/or perinatal edema, Lymphatic malformation 6 |
| RS5945206 |
IKBKG
|
Health Risk |
Conflicting classifications of pathogenicity |
Ectodermal dysplasia and immunodeficiency 1, Ectodermal dysplasia and immunodeficiency 1 |
| RS5945430 |
PLXNA3
|
Health Risk |
Conflicting classifications of pathogenicity |
Hypogonadotropic hypogonadism, Hypogonadotropic hypogonadism |
| RS59461207 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Idiopathic generalized epilepsy, Hyperaldosteronism |
| RS59472972 |
CYP1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Irido-corneo-trabecular dysgenesis, Glaucoma 3A |
| RS59477041 |
TTC21B
|
Health Risk |
Conflicting classifications of pathogenicity |
Jeune thoracic dystrophy, Nephronophthisis |
| RS59493015 |
TMEM216
|
Health Risk |
Conflicting classifications of pathogenicity |
Joubert syndrome 2, TMEM216-related disorder |
| RS59507540 |
SLC25A13
|
Health Risk |
Pathogenic |
Citrin deficiency, Citrin deficiency |
| RS59510579 |
KRT9
|
Health Risk |
Conflicting classifications of pathogenicity |
Palmoplantar keratoderma, epidermolytic |
| RS59520182 |
MAGEC1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS59551486 |
NEFH
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 1, Inborn genetic diseases |
| RS59558623 |
DOCK7
|
Health Risk |
Conflicting classifications of pathogenicity |
Developmental and epileptic encephalopathy, 23 |
| RS5956 |
CD36
|
Health Risk |
Conflicting classifications of pathogenicity |
Platelet-type bleeding disorder 10, Platelet-type bleeding disorder 10 |
| RS59564495 |
LMNA
|
Health Risk |
Likely pathogenic |
Primary dilated cardiomyopathy, Charcot-Marie-Tooth disease type 2 |
| RS59565950 |
GFAP
|
Health Risk |
Pathogenic |
Alexander disease, Spastic paraplegia |
| RS59601651 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Charcot-Marie-Tooth disease type 2 |
| RS59616921 |
KRT9
|
Health Risk |
Pathogenic/Likely pathogenic |
Palmoplantar keratoderma, epidermolytic |
| RS59629244 |
KRT14
|
Health Risk |
Likely pathogenic |
Epidermolysis bullosa simplex, Koebner type |
| RS5964 |
F11
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary factor XI deficiency disease, Plasma factor XI deficiency |