SNP Directory

400,964 genetic variants in our database.

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All (400,964) Health Risk (400,964) Other (47,777) Drug Response (1,898) Trait (128) Protective (50)
RSID Gene Category Clinical Significance Conditions
RS1060499640 FH Health Risk Conflicting classifications of pathogenicity Hereditary leiomyomatosis and renal cell cancer, FH-related disorder
RS1060499641 FH Health Risk Pathogenic Hereditary leiomyomatosis and renal cell cancer, Hereditary cancer-predisposing syndrome
RS1060499642 FH Health Risk Likely pathogenic Hereditary leiomyomatosis and renal cell cancer, Hereditary cancer-predisposing syndrome
RS1060499643 FH Health Risk Pathogenic Hereditary leiomyomatosis and renal cell cancer, Hereditary cancer-predisposing syndrome
RS1060499644 FH Health Risk Pathogenic/Likely pathogenic Hereditary leiomyomatosis and renal cell cancer, Hereditary cancer-predisposing syndrome
RS1060499645 FH Health Risk Pathogenic/Likely pathogenic Hereditary leiomyomatosis and renal cell cancer, Hereditary cancer-predisposing syndrome
RS1060499646 TRPM6 Health Risk Likely pathogenic Intestinal hypomagnesemia 1, Intestinal hypomagnesemia 1
RS1060499647 TSC2 Health Risk Pathogenic Tuberous sclerosis 2, Tuberous sclerosis 2
RS1060499649 TJP2 Health Risk Likely pathogenic Cholestasis, progressive familial intrahepatic
RS1060499651 MYO7A Health Risk Pathogenic Autosomal recessive nonsyndromic hearing loss 2, Autosomal recessive nonsyndromic hearing loss 2
RS1060499652 NEXMIF Health Risk Pathogenic X-linked intellectual disability, Cantagrel type
RS1060499653 PLP1 Health Risk Pathogenic Pelizaeus-Merzbacher disease, Pelizaeus-Merzbacher disease
RS1060499654 COL4A3 Health Risk Pathogenic/Likely pathogenic Autosomal recessive Alport syndrome, Autosomal dominant Alport syndrome
RS1060499655 ZBTB18 Health Risk Pathogenic Intellectual disability, autosomal dominant 22
RS1060499656 SACS Health Risk Likely pathogenic Charlevoix-Saguenay spastic ataxia, Charlevoix-Saguenay spastic ataxia
RS1060499657 UMOD Health Risk Likely pathogenic Familial juvenile hyperuricemic nephropathy type 1, Familial juvenile hyperuricemic nephropathy type 1
RS1060499658 ATRX Health Risk Pathogenic Alpha thalassemia-X-linked intellectual disability syndrome, Alpha thalassemia-X-linked intellectual disability syndrome
RS1060499659 GRIN2B Health Risk Pathogenic/Likely pathogenic Developmental and epileptic encephalopathy, 27
RS1060499660 IQSEC2 Health Risk Pathogenic Intellectual disability, X-linked 1
RS1060499661 KDM5C Health Risk Pathogenic Syndromic X-linked intellectual disability Claes-Jensen type, Syndromic X-linked intellectual disability Claes-Jensen type
RS1060499662 LIG4 Health Risk Likely pathogenic DNA ligase IV deficiency, DNA ligase IV deficiency
RS1060499663 FGFR1 Health Risk Pathogenic Hypogonadotropic hypogonadism 2 with or without anosmia, Hypogonadotropic hypogonadism 2 with or without anosmia
RS1060499665 KDM6A Health Risk Likely pathogenic Kabuki syndrome 2, Kabuki syndrome 2
RS1060499666 PIGA Health Risk Conflicting classifications of pathogenicity Multiple congenital anomalies-hypotonia-seizures syndrome 2, Multiple congenital anomalies-hypotonia-seizures syndrome 2
RS1060499667 VAC14 Health Risk Likely pathogenic Yunis-Varon syndrome, Yunis-Varon syndrome
RS1060499668 ARID1B Health Risk Pathogenic Nicolaides-Baraitser syndrome, Coffin-Siris syndrome 1
RS1060499669 KMT2D Health Risk Pathogenic Kabuki syndrome 1, Kabuki syndrome 1
RS1060499670 SPAST Health Risk Likely pathogenic Hereditary spastic paraplegia 4, Hereditary spastic paraplegia
RS1060499672 AP1S2 Health Risk Pathogenic Pettigrew syndrome, Pettigrew syndrome
RS1060499673 MYBPC3 Health Risk Pathogenic Hypertrophic cardiomyopathy 4, Hypertrophic cardiomyopathy 4
RS1060499676 TSC2 Health Risk Pathogenic/Likely pathogenic Tuberous sclerosis 2, Lymphangiomyomatosis
RS1060499679 GNPTAB Health Risk Likely pathogenic Mucolipidosis type II, Pseudo-Hurler polydystrophy
RS1060499680 GNPTAB Health Risk Pathogenic/Likely pathogenic Mucolipidosis type II, Pseudo-Hurler polydystrophy
RS1060499681 GNPTAB Health Risk Likely pathogenic Mucolipidosis type II, Pseudo-Hurler polydystrophy
RS1060499684 GNPTAB Health Risk Likely pathogenic Mucolipidosis type II, Pseudo-Hurler polydystrophy
RS1060499685 GNPTAB Health Risk Likely pathogenic Mucolipidosis type II, Pseudo-Hurler polydystrophy
RS1060499687 GNPTAB Health Risk Likely pathogenic Mucolipidosis type II, Pseudo-Hurler polydystrophy
RS1060499688 GNPTAB Health Risk Likely pathogenic Mucolipidosis type II, Pseudo-Hurler polydystrophy
RS1060499689 GNPTAB Health Risk Likely pathogenic Mucolipidosis type II, Pseudo-Hurler polydystrophy
RS1060499690 GNPTG Health Risk Likely pathogenic GNPTG-mucolipidosis, Mucolipidosis
RS1060499691 GNPTG Health Risk Likely pathogenic GNPTG-mucolipidosis, GNPTG-mucolipidosis
RS1060499692 GHR Health Risk Pathogenic Laron-type isolated somatotropin defect, Laron-type isolated somatotropin defect
RS1060499694 COL4A5 Health Risk Pathogenic X-linked Alport syndrome, X-linked Alport syndrome
RS1060499695 THRB Health Risk Likely pathogenic Thyroid hormone resistance, generalized
RS1060499696 COL4A3 Health Risk Pathogenic Hematuria, benign familial
RS1060499697 SLC34A3 Health Risk Likely pathogenic Autosomal recessive hypophosphatemic bone disease, Autosomal recessive hypophosphatemic bone disease
RS1060499699 PKD1 Health Risk Conflicting classifications of pathogenicity Polycystic kidney disease, adult type
RS1060499701 HEXB Health Risk Pathogenic Sandhoff disease, Sandhoff disease
RS1060499702 PKD1 Health Risk Pathogenic Polycystic kidney disease, adult type
RS1060499703 NPHS2 Health Risk Pathogenic Nephrotic syndrome, type 2
RS1060499704 PKD1 Health Risk Likely pathogenic Polycystic kidney disease, adult type
RS1060499708 DGKE Health Risk Pathogenic Immunoglobulin-mediated membranoproliferative glomerulonephritis, Immunoglobulin-mediated membranoproliferative glomerulonephritis
RS1060499709 DGKE Health Risk Likely pathogenic Immunoglobulin-mediated membranoproliferative glomerulonephritis, Immunoglobulin-mediated membranoproliferative glomerulonephritis
RS1060499710 COL4A5 Health Risk Likely pathogenic X-linked Alport syndrome, X-linked Alport syndrome
RS1060499714 CDH23 Health Risk Likely pathogenic Usher syndrome type 1D, Pituitary adenoma 5
RS1060499715 BCKDHB Health Risk Likely pathogenic Maple syrup urine disease, Maple syrup urine disease
RS1060499716 MYO7A Health Risk Likely pathogenic Usher syndrome type 1, Usher syndrome type 1
RS1060499717 FOXL2 Health Risk Pathogenic Blepharophimosis, ptosis
RS1060499718 PKD1 Health Risk Pathogenic Polycystic kidney disease, adult type
RS1060499724 KMT2D Health Risk Pathogenic Kabuki syndrome 1, Kabuki syndrome 1
RS1060499726 FBP1 Health Risk Pathogenic Fructose-biphosphatase deficiency, Fructose-biphosphatase deficiency
RS1060499728 MYH8 Health Risk Conflicting classifications of pathogenicity Hecht syndrome, Hecht syndrome
RS1060499733 DHX30 Health Risk Pathogenic 7 conditions, Neurodevelopmental disorder with severe motor impairment and absent language
RS1060499734 VARS1 Health Risk Conflicting classifications of pathogenicity Abnormal brain morphology, Neurodevelopmental disorder with microcephaly
RS1060499735 CPLX1 Health Risk Likely pathogenic Abnormal brain morphology, Developmental and epileptic encephalopathy
RS1060499736 SMARCA1 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499737 DHX37 Health Risk Likely pathogenic Abnormal brain morphology, Neurodevelopmental disorder with brain anomalies and with or without vertebral or cardiac anomalies
RS1060499738 ACTL6B Health Risk Likely pathogenic Intellectual disability, Global developmental delay
RS1060499739 CEP97 Health Risk Likely pathogenic Global developmental delay, Intellectual disability
RS1060499740 CINP Health Risk Likely pathogenic Intellectual disability, Seizure
RS1060499742 ANK3 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499743 ARHGAP21 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499744 ASH2L Health Risk Likely pathogenic Global developmental delay, Intellectual disability
RS1060499745 CDK10 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499746 GTF3C1 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499747 HELZ Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499748 KLHL15 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499749 PTPRT Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499750 SLITRK5 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499751 SNAPIN Health Risk Likely pathogenic Abnormal brain morphology, See cases
RS1060499752 TTC1 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499753 UBQLN1 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499754 ULK2 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499755 ALDH7A1 Health Risk Likely pathogenic Abnormal brain morphology, Pyridoxine-dependent epilepsy
RS1060499756 AP4B1 Health Risk Likely pathogenic Abnormal brain morphology, Spastic paraplegia
RS1060499757 ASPM Health Risk Likely pathogenic Microcephaly, Microcephaly
RS1060499758 ASPM Health Risk Likely pathogenic Microcephaly, Microcephaly
RS1060499759 ATRX Health Risk Likely pathogenic Global developmental delay, Microcephaly
RS1060499760 ATRX Health Risk Conflicting classifications of pathogenicity Microcephaly, Global developmental delay
RS1060499761 GALC Health Risk Conflicting classifications of pathogenicity Abnormal brain morphology, Galactosylceramide beta-galactosidase deficiency
RS1060499762 LARP7 Health Risk Likely pathogenic Abnormal brain morphology, Microcephalic primordial dwarfism
RS1060499763 PIGN Health Risk Conflicting classifications of pathogenicity Abnormal brain morphology, Multiple congenital anomalies-hypotonia-seizures syndrome 1
RS1060499764 PLA2G6 Health Risk Likely pathogenic Abnormal brain morphology, Infantile neuroaxonal dystrophy
RS1060499765 PLCB1 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499766 POMT2 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499768 SPG11 Health Risk Pathogenic Abnormal brain morphology, Hereditary spastic paraplegia 11
RS1060499769 SYNE1 Health Risk Conflicting classifications of pathogenicity Abnormal brain morphology, Emery-Dreifuss muscular dystrophy 4
RS1060499770 ZEB2 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
RS1060499771 AP4B1 Health Risk Likely pathogenic Abnormal brain morphology, Spastic paraplegia
RS1060499772 DARS1 Health Risk Likely pathogenic Abnormal brain morphology, Abnormal brain morphology
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