RS405509 APOE
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What This Variant Does
"obstructive sleep apnea rs405509 Significant Alzheimer's disease associations with were found for rs...
Associated Conditions
Coronary artery disease
severe
susceptibility to
Warfarin response
Coronary artery disease
severe
susceptibility to
Warfarin response
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Linoleic acid to total fatty acids percentage | T | — | 1E-40 | PubMed |
| Linoleic acid to total fatty acids percentage | T | — | 2E-39 | PubMed |
| Alzheimer's disease | G | OR: 0.68 | 3E-38 | PubMed |
| APOE protein levels | — | OR: 0.38 | 3E-32 | PubMed |
| Polyunsaturated fatty acids to saturated fatty acids ratio | T | — | 7E-25 | PubMed |
| Linoleic acid to total fatty acids percentage | T | — | 3E-24 | PubMed |
| Linoleic acid to total fatty acids percentage | T | — | 5E-22 | PubMed |
| Alzheimer's disease | T | OR: 1.61 | 2E-21 | PubMed |
| Total fatty acid levels | T | — | 2E-20 | PubMed |
| Linoleic acid to total fatty acids percentage | T | — | 3E-20 | PubMed |
| Polyunsaturated fatty acids to saturated fatty acids ratio | T | — | 3E-17 | PubMed |
| Linoleic acid to total fatty acids percentage | T | — | 4E-17 | PubMed |
| Monounsaturated fatty acid levels | T | — | 1E-16 | PubMed |
| Polyunsaturated fatty acids to saturated fatty acids ratio | T | — | 1E-13 | PubMed |
| Degree of unsaturation | T | — | 1E-12 | PubMed |
| Polyunsaturated fatty acids to saturated fatty acids ratio | T | — | 1E-12 | PubMed |
| Total fatty acid levels | T | — | 1E-12 | PubMed |
| HDL cholesterol levels x short total sleep time interaction (2df test) | — | β: 0.008 | 3E-12 | PubMed |
| Serum metabolite levels (CMS) | — | β: 0.044 | 4E-12 | PubMed |
| Monounsaturated fatty acid levels | T | — | 7E-12 | PubMed |
ClinVar Assertions (1)
NC_000019.10:g.44905579=
Population Frequencies
1kG AFR
23.7%
1kG ALL
47.2%
1kG AMR
49.7%
1kG EAS
33.3%
1kG EUR
48.4%
1kG SAS
44.6%
Other Variants in APOE