Uveal Melanoma

Cancer 80 variants 24 genes

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Associated Genes (24)

CYP2D6 MGST3 HERC2 IRF4 CSPP1 NDUFS2 ERCC6 CPLANE1 VLDLR SMARCA4 CC2D1A ABCB7 KANK1 ARID4A GALT CAPN1 IFT122 EXOSC9 ASAH1 PITRM1 TCTN2 BAP1 MBD4 SLC27A5

Associated Variants (80)

RSID	Gene	Risk Allele	Odds Ratio	Evidence
RS551143	—	A	—	exploratory
RS3892097	CYP2D6	—	—	exploratory
RS8133	MGST3	—	—	exploratory
RS142100881	—	G	—	exploratory
RS12913832	HERC2	A	—	exploratory
RS421284	—	T	—	exploratory
RS11707457	—	T	—	exploratory
RS113515519	—	T	3.79	moderate
RS17184817	—	G	2.52	moderate
RS11074306	—	A	1.85	moderate
RS3759710	—	C	1.78	moderate
RS62080688	—	G	1.77	moderate
RS12203592	IRF4	T	1.76	moderate
RS146125348	—	C	1.73	moderate
RS452932	—	C	1.72	moderate
RS370348	—	G	1.59	moderate
RS9307941	—	T	1.52	moderate
RS2488636	—	G	1.52	moderate
RS6733440	—	G	1.51	moderate
RS4743170	—	G	1.47	moderate
RS71464210	—	A	1.45	moderate
RS12163644	—	A	1.45	moderate
RS11197576	—	T	1.43	moderate
RS35257692	—	G	1.39	moderate
RS6710583	—	T	1.38	moderate
RS8038456	—	G	1.37	moderate
RS13013614	—	A	1.36	moderate
RS7846812	—	T	0.68	moderate
RS285902	—	A	0.65	moderate
RS1129038	—	C	0.56	moderate
RS760205035	CSPP1	—	—	strong
RS190184430	NDUFS2	—	—	strong
RS145720191	ERCC6	—	—	strong
RS199810663	CPLANE1	—	—	strong
RS141850403	VLDLR	—	—	strong
RS117611401	SMARCA4	—	—	strong
RS201251295	CC2D1A	—	—	strong
RS61323727	ABCB7	—	—	strong
RS76738278	KANK1	—	—	strong
RS62621193	ARID4A	—	—	strong
RS151309174	GALT	—	—	strong
RS17883283	CAPN1	—	—	strong
RS200915373	IFT122	—	—	strong
RS151134983	EXOSC9	—	—	strong
RS771628836	ASAH1	—	—	strong
RS190434719	PITRM1	—	—	strong
RS141752910	TCTN2	—	—	strong
RS1705120040	BAP1	—	—	strong
RS778697654	MBD4	—	—	strong
RS200252519	SLC27A5	—	—	strong

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