| RS1057519430 |
DDX3X
|
Health Risk |
Pathogenic |
Intellectual disability, X-linked 102 |
| RS1057519431 |
DDX3X
|
Health Risk |
Pathogenic |
Intellectual disability, X-linked 102 |
| RS1057519432 |
NALCN
|
Health Risk |
Likely pathogenic |
Congenital contractures of the limbs and face, hypotonia |
| RS1057519433 |
NALCN
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital contractures of the limbs and face, hypotonia |
| RS1057519434 |
NR2F1
|
Health Risk |
Pathogenic |
Bosch-Boonstra-Schaaf optic atrophy syndrome, Bosch-Boonstra-Schaaf optic atrophy syndrome |
| RS1057519435 |
ZBTB20
|
Health Risk |
Pathogenic/Likely pathogenic |
Primrose syndrome, SHORT syndrome |
| RS1057519436 |
DHX30
|
Health Risk |
Pathogenic |
6 conditions, Neurodevelopmental disorder with severe motor impairment and absent language |
| RS1057519437 |
EBF3
|
Health Risk |
Pathogenic |
Renal tubular dysgenesis, Neurogenic bladder |
| RS1057519439 |
DNAH7
|
Health Risk |
Pathogenic |
Abnormal muscle tone, Seizure |
| RS1057519440 |
GSPT2
|
Health Risk |
Pathogenic |
Seizure, Delayed speech and language development |
| RS1057519441 |
GUCY2C
|
Health Risk |
Pathogenic |
Abnormal biliary tract morphology, Asplenia |
| RS1057519442 |
SLC30A7
|
Health Risk |
Pathogenic |
Joubert syndrome 1, Joubert syndrome 1 |
| RS1057519443 |
MPP4
|
Health Risk |
Pathogenic |
7 conditions, 7 conditions |
| RS1057519444 |
SYN3
|
Health Risk |
Pathogenic |
Global developmental delay, Cerebellar vermis atrophy |
| RS1057519447 |
FBXL4
|
Health Risk |
Pathogenic/Likely pathogenic |
Mitochondrial DNA depletion syndrome 13, Mitochondrial DNA depletion syndrome 13 |
| RS1057519448 |
NAA10
|
Health Risk |
Likely pathogenic |
Ogden syndrome, Ogden syndrome |
| RS1057519449 |
SLC13A5
|
Health Risk |
Likely pathogenic |
Developmental and epileptic encephalopathy, 25 |
| RS1057519450 |
ACOT1
|
Health Risk |
Pathogenic |
Generalized hypotonia, Generalized hypotonia |
| RS1057519451 |
NRXN3
|
Health Risk |
Pathogenic |
Short stature, Relative macrocephaly |
| RS1057519452 |
USP19
|
Health Risk |
Pathogenic |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS1057519453 |
KCND3
|
Health Risk |
Pathogenic |
Spinocerebellar ataxia type 19/22, Spinocerebellar ataxia type 19/22 |
| RS1057519454 |
PMPCA
|
Health Risk |
Pathogenic |
Autosomal recessive spinocerebellar ataxia 2, Autosomal recessive spinocerebellar ataxia 2 |
| RS1057519455 |
POLR1C
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypomyelinating leukodystrophy 11, Treacher Collins syndrome 3 |
| RS1057519456 |
POLR1C
|
Health Risk |
Pathogenic |
Hypomyelinating leukodystrophy 11, Hypomyelinating leukodystrophy 11 |
| RS1057519457 |
SCN1B
|
Health Risk |
Pathogenic |
Cardiomyopathy, Cardiomyopathy |
| RS1057519458 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS1057519459 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS1057519460 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS1057519461 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS1057519462 |
HEXA
|
Health Risk |
Conflicting classifications of pathogenicity |
Tay-Sachs disease, Tay-Sachs disease |
| RS1057519463 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS1057519464 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS1057519465 |
HEXA
|
Health Risk |
Likely pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS1057519466 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS1057519467 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS1057519468 |
HEXA
|
Health Risk |
Pathogenic |
Tay-Sachs disease, Tay-Sachs disease |
| RS1057519469 |
CYP27A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cholestanol storage disease, Cholestanol storage disease |
| RS1057519471 |
FOXC1
|
Health Risk |
Pathogenic |
Axenfeld-Rieger syndrome type 3, Axenfeld-Rieger syndrome type 3 |
| RS1057519472 |
FOXC1
|
Health Risk |
Pathogenic |
Axenfeld-Rieger syndrome type 3, Axenfeld-Rieger syndrome type 3 |
| RS1057519474 |
FOXC1
|
Health Risk |
Likely pathogenic |
Axenfeld-Rieger syndrome type 3, Axenfeld-Rieger syndrome type 3 |
| RS1057519475 |
FOXC1
|
Health Risk |
Pathogenic |
Axenfeld-Rieger syndrome type 3, Axenfeld-Rieger syndrome type 3 |
| RS1057519477 |
FOXC1
|
Health Risk |
Pathogenic |
Anterior segment dysgenesis 3, Anterior segment dysgenesis 3 |
| RS1057519478 |
FOXC1
|
Health Risk |
Pathogenic |
Axenfeld-Rieger syndrome type 3, Axenfeld-Rieger syndrome type 3 |
| RS1057519479 |
FOXC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Axenfeld-Rieger syndrome type 3, Hypertelorism and tetralogy of fallot |
| RS1057519480 |
FOXC1
|
Health Risk |
Pathogenic |
Axenfeld-Rieger syndrome type 3, Anterior segment dysgenesis 3 |
| RS1057519481 |
FOXC1
|
Health Risk |
Pathogenic |
Axenfeld-Rieger syndrome type 3, Axenfeld-Rieger syndrome type 3 |
| RS1057519482 |
FOXC1
|
Health Risk |
Pathogenic |
Axenfeld-Rieger syndrome type 3, Axenfeld-Rieger syndrome type 3 |
| RS1057519483 |
PITX2
|
Health Risk |
Pathogenic |
Axenfeld-Rieger syndrome type 1, Axenfeld-Rieger syndrome type 1 |
| RS1057519484 |
PITX2
|
Health Risk |
Pathogenic |
Axenfeld-Rieger syndrome type 1, Axenfeld-Rieger syndrome type 1 |
| RS1057519485 |
PITX2
|
Health Risk |
Likely pathogenic |
Axenfeld-Rieger syndrome type 1, Anterior segment dysgenesis 4 |
| RS1057519487 |
PITX2
|
Health Risk |
Pathogenic |
Axenfeld-Rieger syndrome type 1, Axenfeld-Rieger syndrome type 1 |
| RS1057519488 |
PITX2
|
Health Risk |
Pathogenic |
Axenfeld-Rieger syndrome type 1, Axenfeld-Rieger syndrome type 1 |
| RS1057519489 |
PITX2
|
Health Risk |
Pathogenic |
Axenfeld-Rieger syndrome type 1, Axenfeld-Rieger syndrome type 1 |
| RS1057519491 |
IMPA1
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal recessive 59 |
| RS1057519492 |
NLRP1
|
Health Risk |
Pathogenic |
Corneal intraepithelial dyskeratosis-palmoplantar hyperkeratosis-laryngeal dyskeratosis syndrome, Corneal intraepithelial dyskeratosis-palmoplantar hyperkeratosis-laryngeal dyskeratosis syndrome |
| RS1057519493 |
NLRP1
|
Health Risk |
Likely pathogenic |
Corneal intraepithelial dyskeratosis-palmoplantar hyperkeratosis-laryngeal dyskeratosis syndrome, Corneal intraepithelial dyskeratosis-palmoplantar hyperkeratosis-laryngeal dyskeratosis syndrome |
| RS1057519495 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Breast-ovarian cancer |
| RS1057519496 |
BRCA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary breast ovarian cancer syndrome, Hereditary cancer-predisposing syndrome |
| RS1057519498 |
ASXL3
|
Health Risk |
Pathogenic |
Severe feeding difficulties-failure to thrive-microcephaly due to ASXL3 deficiency syndrome, Severe feeding difficulties-failure to thrive-microcephaly due to ASXL3 deficiency syndrome |
| RS1057519499 |
SMC1A
|
Health Risk |
Likely pathogenic |
Congenital muscular hypertrophy-cerebral syndrome, Congenital muscular hypertrophy-cerebral syndrome |
| RS1057519501 |
STXBP1
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy, 4 |
| RS1057519502 |
FBN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Marfan syndrome, Cardiovascular phenotype |
| RS1057519503 |
NCF1
|
Health Risk |
Pathogenic |
Hypertrophic cardiomyopathy 4, Hypertrophic cardiomyopathy 4 |
| RS1057519506 |
STIM1
|
Health Risk |
Pathogenic |
Combined immunodeficiency due to STIM1 deficiency, Combined immunodeficiency due to STIM1 deficiency |
| RS1057519507 |
PEX12
|
Health Risk |
Pathogenic |
Peroxisome biogenesis disorder 3A (Zellweger), Peroxisome biogenesis disorder 3A (Zellweger) |
| RS1057519508 |
KDF1
|
Health Risk |
Pathogenic |
Ectodermal dysplasia 12, hypohidrotic/hair/tooth/nail type |
| RS1057519509 |
BRPF1
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with dysmorphic facies and ptosis, Intellectual developmental disorder with dysmorphic facies and ptosis |
| RS1057519510 |
BRPF1
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with dysmorphic facies and ptosis, Inborn genetic diseases |
| RS1057519511 |
BRPF1
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with dysmorphic facies and ptosis, Neurodevelopmental disorder |
| RS1057519512 |
BRPF1
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with dysmorphic facies and ptosis, Intellectual developmental disorder with dysmorphic facies and ptosis |
| RS1057519513 |
BRPF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual developmental disorder with dysmorphic facies and ptosis, See cases |
| RS1057519514 |
BRPF1
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with dysmorphic facies and ptosis, Intellectual developmental disorder with dysmorphic facies and ptosis |
| RS1057519515 |
BRPF1
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with dysmorphic facies and ptosis, Intellectual developmental disorder with dysmorphic facies and ptosis |
| RS1057519516 |
BRPF1
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with dysmorphic facies and ptosis, Intellectual developmental disorder with dysmorphic facies and ptosis |
| RS1057519517 |
BRPF1
|
Health Risk |
Pathogenic |
Intellectual developmental disorder with dysmorphic facies and ptosis, Intellectual developmental disorder with dysmorphic facies and ptosis |
| RS1057519518 |
EBF3
|
Health Risk |
Likely pathogenic |
Hypotonia, ataxia |
| RS1057519519 |
EBF3
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypotonia, ataxia |
| RS1057519520 |
EBF3
|
Health Risk |
Pathogenic |
Hypotonia, ataxia |
| RS1057519521 |
EBF3
|
Health Risk |
Pathogenic |
Hypotonia, ataxia |
| RS1057519522 |
EBF3
|
Health Risk |
Pathogenic |
Hypotonia, ataxia |
| RS1057519523 |
SCN2A
|
Health Risk |
Pathogenic |
Malignant migrating partial seizures of infancy, Malignant migrating partial seizures of infancy |
| RS1057519524 |
SCN2A
|
Health Risk |
Likely pathogenic |
Epileptic encephalopathy, Developmental and epileptic encephalopathy |
| RS1057519525 |
SCN2A
|
Health Risk |
Likely pathogenic |
Focal epilepsy, SCN2A-related disorder |
| RS1057519526 |
SCN2A
|
Health Risk |
Pathogenic/Likely pathogenic |
Epileptic encephalopathy, Developmental and epileptic encephalopathy |
| RS1057519527 |
SCN2A
|
Health Risk |
Likely pathogenic |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS1057519528 |
SCN2A
|
Health Risk |
Likely pathogenic |
Epileptic encephalopathy, Developmental and epileptic encephalopathy |
| RS1057519529 |
SCN1A
|
Health Risk |
Pathogenic |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS1057519530 |
SCN1A
|
Health Risk |
Likely pathogenic |
Severe myoclonic epilepsy in infancy, Severe myoclonic epilepsy in infancy |
| RS1057519531 |
SCN1A
|
Health Risk |
Pathogenic |
Severe myoclonic epilepsy in infancy, Early-infantile DEE |
| RS1057519533 |
SCN1A
|
Health Risk |
Likely pathogenic |
Severe myoclonic epilepsy in infancy, Severe myoclonic epilepsy in infancy |
| RS1057519534 |
SCN1A
|
Health Risk |
Pathogenic |
Severe myoclonic epilepsy in infancy, Severe myoclonic epilepsy in infancy |
| RS1057519535 |
KCNQ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Epileptic encephalopathy, Inborn genetic diseases |
| RS1057519536 |
KCNQ2
|
Health Risk |
Pathogenic |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS1057519537 |
STXBP1
|
Health Risk |
Pathogenic |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS1057519538 |
STXBP1
|
Health Risk |
Pathogenic |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS1057519539 |
STXBP1
|
Health Risk |
Pathogenic |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS1057519540 |
SCN8A
|
Health Risk |
Pathogenic/Likely pathogenic |
Epileptic encephalopathy, Developmental and epileptic encephalopathy |
| RS1057519541 |
CDKL5
|
Health Risk |
Pathogenic |
Focal epilepsy, Focal epilepsy |
| RS1057519542 |
CDKL5
|
Health Risk |
Pathogenic |
Epileptic encephalopathy, Epileptic encephalopathy |
| RS1057519543 |
MECP2
|
Health Risk |
Likely pathogenic |
Focal epilepsy, Rett syndrome |