| RS72549373 |
CYP1B1
|
Health Risk |
Pathogenic/Likely pathogenic |
Congenital glaucoma, Congenital glaucoma |
| RS72549376 |
CYP1B1
|
Health Risk |
Pathogenic |
Congenital glaucoma, Anterior segment dysgenesis |
| RS72549379 |
CYP1B1
|
Health Risk |
Pathogenic |
Primary congenital glaucoma, Congenital glaucoma |
| RS72549380 |
CYP1B1
|
Health Risk |
Pathogenic |
Congenital glaucoma, Glaucoma 3A |
| RS72549381 |
CYP1B1
|
Health Risk |
Pathogenic |
Congenital glaucoma, Anterior segment dysgenesis 6 |
| RS72549382 |
CYP1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Glaucoma 3A, Congenital glaucoma |
| RS72549383 |
CYP1B1
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital glaucoma, Irido-corneo-trabecular dysgenesis |
| RS72549387 |
CYP1B1
|
Health Risk |
Pathogenic |
Irido-corneo-trabecular dysgenesis, Glaucoma 3A |
| RS72549388 |
CYP1B1
|
Health Risk |
Pathogenic |
Congenital glaucoma, Anterior segment dysgenesis 6 |
| RS72549389 |
CYP1B1
|
Health Risk |
Pathogenic |
Anterior segment dysgenesis 6, Primary congenital glaucoma |
| RS72549394 |
ABCB11
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive familial intrahepatic cholestasis, Progressive familial intrahepatic cholestasis type 2 |
| RS72549395 |
ABCB11
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive familial intrahepatic cholestasis type 2, ABCB11-related disorder |
| RS72549396 |
ABCB11
|
Health Risk |
Pathogenic/Likely pathogenic |
Benign recurrent intrahepatic cholestasis type 2, Progressive familial intrahepatic cholestasis type 2 |
| RS72549397 |
ABCB11
|
Health Risk |
Pathogenic |
Progressive familial intrahepatic cholestasis type 2, Benign recurrent intrahepatic cholestasis type 2 |
| RS72549398 |
ABCB11
|
Health Risk |
Pathogenic |
Abnormal liver function tests during pregnancy, Pruritus |
| RS72549399 |
ABCB11
|
Health Risk |
Pathogenic |
Progressive familial intrahepatic cholestasis type 2, Benign recurrent intrahepatic cholestasis type 2 |
| RS72549401 |
ABCB11
|
Health Risk |
Pathogenic |
Progressive familial intrahepatic cholestasis type 2, Benign recurrent intrahepatic cholestasis type 2 |
| RS72549402 |
ABCB11
|
Health Risk |
Pathogenic |
Progressive familial intrahepatic cholestasis type 2, Benign recurrent intrahepatic cholestasis type 2 |
| RS72549405 |
HYCC1
|
Health Risk |
Pathogenic |
Hypomyelination and Congenital Cataract, Hypomyelination and Congenital Cataract |
| RS72549406 |
HYCC1
|
Health Risk |
Pathogenic |
Hypomyelination and Congenital Cataract, Hypomyelination and Congenital Cataract |
| RS72549407 |
HYCC1
|
Health Risk |
Pathogenic |
Hypomyelination and Congenital Cataract, Hypomyelination and Congenital Cataract |
| RS72549410 |
SCN5A
|
Health Risk |
Pathogenic |
Congenital long QT syndrome, Long QT syndrome |
| RS72549411 |
SCN5A
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1E, Progressive familial heart block |
| RS72549413 |
SCN5A
|
Health Risk |
Likely pathogenic |
Brugada syndrome 1, Brugada syndrome 1 |
| RS72549417 |
RYR2
|
Health Risk |
Conflicting classifications of pathogenicity |
Arrhythmogenic right ventricular dysplasia 2, Cardiomyopathy |
| RS72549418 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome |
| RS72549419 |
KCNH2
|
Health Risk |
Conflicting classifications of pathogenicity |
Long QT syndrome, Cardiac arrhythmia |
| RS72550218 |
KCNE2
|
Health Risk |
Conflicting classifications of pathogenicity |
Atrial fibrillation, familial |
| RS72550822 |
KIT
|
Health Risk |
Conflicting classifications of pathogenicity |
Gastrointestinal stromal tumor, Hereditary cancer-predisposing syndrome |
| RS72550866 |
MASP2
|
Health Risk |
Conflicting classifications of pathogenicity |
MASP2-related disorder, MASP2-related disorder |
| RS72550870 |
MASP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Immunodeficiency due to MASP-2 deficiency, MASP2-related disorder |
| RS72550890 |
FUS
|
Health Risk |
Conflicting classifications of pathogenicity |
Amyotrophic lateral sclerosis type 6, Tremor |
| RS72551306 |
ABCB11
|
Health Risk |
Likely pathogenic |
Benign recurrent intrahepatic cholestasis type 2, Benign recurrent intrahepatic cholestasis type 2 |
| RS72551312 |
CYP27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cholestanol storage disease, CYP27A1-related disorder |
| RS72551313 |
CYP27A1
|
Health Risk |
Pathogenic |
Cholestanol storage disease, Cholestanol storage disease |
| RS72551314 |
CYP27A1
|
Health Risk |
Pathogenic |
Cholestanol storage disease, Cholestanol storage disease |
| RS72551315 |
CYP27A1
|
Health Risk |
Pathogenic |
Cholestanol storage disease, Cholestanol storage disease |
| RS72551316 |
CYP27A1
|
Health Risk |
Pathogenic |
Cholestanol storage disease, Cholestanol storage disease |
| RS72551317 |
CYP27A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cholestanol storage disease, Cholestanol storage disease |
| RS72551318 |
CYP27A1
|
Health Risk |
Pathogenic |
Cholestanol storage disease, Cholestanol storage disease |
| RS72551319 |
CYP27A1
|
Health Risk |
Pathogenic |
Cholestanol storage disease, Cholestanol storage disease |
| RS72551320 |
CYP27A1
|
Health Risk |
Pathogenic |
Cholestanol storage disease, Cholestanol storage disease |
| RS72551321 |
CYP27A1
|
Health Risk |
Pathogenic |
Cholestanol storage disease, Cholestanol storage disease |
| RS72551322 |
CYP27A1
|
Health Risk |
Pathogenic |
Cholestanol storage disease, CYP27A1-related disorder |
| RS72551323 |
CYP27A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Cholestanol storage disease, CYP27A1-related disorder |
| RS72551340 |
UGT1A1
|
Health Risk |
Pathogenic |
Crigler-Najjar syndrome, Crigler-Najjar syndrome |
| RS72551341 |
UGT1A1
|
Health Risk |
Conflicting classifications of pathogenicity; other |
Crigler-Najjar syndrome, type II |
| RS72551343 |
UGT1A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Crigler-Najjar syndrome, Inborn genetic diseases |
| RS72551345 |
UGT1A1
|
Health Risk |
Pathogenic |
Crigler-Najjar syndrome, type II |
| RS72551348 |
covers 10 genes, none of which curated to show dosage sensitivity
|
Health Risk |
Likely pathogenic |
Crigler-Najjar syndrome, type II |
| RS72551349 |
UGT1A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Crigler-Najjar syndrome type 1, Gilbert syndrome |
| RS72551350 |
UGT1A1
|
Health Risk |
Pathogenic |
— |
| RS72551351 |
covers 10 genes, none of which curated to show dosage sensitivity
|
Health Risk |
Likely pathogenic |
Crigler-Najjar syndrome type 1, Gilbert syndrome |
| RS72551353 |
UGT1A1
|
Health Risk |
Pathogenic |
Crigler-Najjar syndrome type 1, Crigler-Najjar syndrome |
| RS72551360 |
UGT1A1
|
Health Risk |
Conflicting classifications of pathogenicity |
— |
| RS72551362 |
PPARG
|
Health Risk |
Pathogenic |
PPARG-related familial partial lipodystrophy, PPARG-related familial partial lipodystrophy |
| RS72551363 |
PPARG
|
Health Risk |
Pathogenic |
PPARG-related familial partial lipodystrophy, PPARG-related familial partial lipodystrophy |
| RS72551364 |
PPARG
|
Health Risk |
Pathogenic/Likely pathogenic |
PPARG-related familial partial lipodystrophy, PPARG-related familial partial lipodystrophy |
| RS72552027 |
SCN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Generalized epilepsy with febrile seizures plus |
| RS72552028 |
SCN1B
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 5, Cardiovascular phenotype |
| RS72552029 |
KCNJ2
|
Health Risk |
Conflicting classifications of pathogenicity |
Short QT syndrome type 3, Andersen Tawil syndrome |
| RS72552053 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS72552255 |
ATP7B
|
Health Risk |
Pathogenic |
Wilson disease, Inborn genetic diseases |
| RS72552258 |
ALDH6A1
|
Health Risk |
Pathogenic |
Methylmalonate semialdehyde dehydrogenase deficiency, Methylmalonate semialdehyde dehydrogenase deficiency |
| RS72552259 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Epileptic encephalopathy |
| RS72552271 |
SLC16A1
|
Health Risk |
Conflicting classifications of pathogenicity |
Metabolic myopathy due to lactate transporter defect, Metabolic myopathy due to lactate transporter defect |
| RS72552272 |
SLC7A7
|
Health Risk |
Pathogenic |
Lysinuric protein intolerance, Lysinuric protein intolerance |
| RS72552281 |
ALDH5A1
|
Health Risk |
Pathogenic |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS72552282 |
ALDH5A1
|
Health Risk |
Likely pathogenic |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS72552283 |
ALDH5A1
|
Health Risk |
Likely pathogenic |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS72552284 |
ALDH5A1
|
Health Risk |
Pathogenic |
Succinate-semialdehyde dehydrogenase deficiency, Succinate-semialdehyde dehydrogenase deficiency |
| RS72552285 |
ATP7B
|
Health Risk |
Pathogenic/Likely pathogenic |
Wilson disease, Wilson disease |
| RS72552291 |
GPD1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 2, Death in infancy |
| RS72552292 |
GPD1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 2, Cardiovascular phenotype |
| RS72552293 |
GPD1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 2, SUDDEN INFANT DEATH SYNDROME |
| RS72552294 |
GPD1L
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 2, Brugada syndrome |
| RS72552295 |
OTC
|
Health Risk |
Pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS72552296 |
OTC
|
Health Risk |
Pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS72552297 |
OTC
|
Health Risk |
Pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS72552298 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS72552299 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS72552300 |
OTC
|
Health Risk |
Pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS72552301 |
OTC
|
Health Risk |
Pathogenic |
— |
| RS72552302 |
OTC
|
Health Risk |
Likely pathogenic |
Ornithine carbamoyltransferase deficiency, Ornithine carbamoyltransferase deficiency |
| RS72552322 |
CHEK2
|
Health Risk |
Likely pathogenic |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS72552323 |
CHEK2
|
Health Risk |
Conflicting classifications of pathogenicity |
Hereditary cancer-predisposing syndrome, Familial cancer of breast |
| RS72552377 |
FANCA
|
Health Risk |
Conflicting classifications of pathogenicity |
Fanconi anemia, Fanconi anemia complementation group A |
| RS72552401 |
SERPINA1
|
Health Risk |
Conflicting classifications of pathogenicity |
Alpha-1-antitrypsin deficiency, SERPINA1-related disorder |
| RS72552713 |
ABCG2
|
Health Risk |
association |
BLOOD GROUP, JUNIOR SYSTEM |
| RS72552722 |
SLC22A5
|
Health Risk |
Pathogenic/Likely pathogenic |
Renal carnitine transport defect, SLC22A5-related disorder |
| RS72552723 |
SLC22A5
|
Health Risk |
Pathogenic/Likely pathogenic |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS72552724 |
SLC22A5
|
Health Risk |
Pathogenic/Likely pathogenic |
Renal carnitine transport defect, SLC22A5-related disorder |
| RS72552725 |
SLC22A5
|
Health Risk |
Pathogenic |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS72552726 |
SLC22A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal carnitine transport defect, Carnitine deficiency |
| RS72552727 |
SLC22A5
|
Health Risk |
Pathogenic |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS72552728 |
SLC22A5
|
Health Risk |
Pathogenic/Likely pathogenic |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS72552729 |
SLC22A5
|
Health Risk |
Pathogenic/Likely pathogenic |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS72552730 |
SLC22A5
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS72552731 |
SLC22A5
|
Health Risk |
Pathogenic |
Renal carnitine transport defect, Renal carnitine transport defect |
| RS72552732 |
SLC22A5
|
Health Risk |
Pathogenic |
Renal carnitine transport defect, Inborn genetic diseases |