| RS606231410 |
COL11A2
|
Health Risk |
Pathogenic |
Nonsyndromic Deafness, Autosomal recessive nonsyndromic hearing loss 53 |
| RS606231411 |
POU1F1
|
Health Risk |
Likely pathogenic |
Pituitary hormone deficiency, combined |
| RS606231412 |
GHRHR
|
Health Risk |
Likely pathogenic |
Isolated growth hormone deficiency type IB, Isolated growth hormone deficiency type IB |
| RS606231413 |
GHRHR
|
Health Risk |
Likely pathogenic |
Isolated growth hormone deficiency type IB, Isolated growth hormone deficiency type IB |
| RS606231416 |
BRF1
|
Health Risk |
Pathogenic/Likely pathogenic |
Cerebellar-facial-dental syndrome, Inborn genetic diseases |
| RS606231417 |
CTLA4
|
Health Risk |
Pathogenic |
Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency, Inborn genetic diseases |
| RS606231418 |
CTLA4
|
Health Risk |
Pathogenic |
Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency, Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency |
| RS606231419 |
CTLA4
|
Health Risk |
Pathogenic |
Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency, Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency |
| RS606231420 |
CTLA4
|
Health Risk |
Pathogenic |
Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency, Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency |
| RS606231421 |
CTLA4
|
Health Risk |
Likely pathogenic |
Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency, Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency |
| RS606231422 |
CTLA4
|
Health Risk |
Pathogenic/Likely pathogenic |
Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency, Autoimmune lymphoproliferative syndrome due to CTLA4 haploinsufficiency |
| RS606231423 |
RDH11
|
Health Risk |
Pathogenic |
Retinitis pigmentosa-juvenile cataract-short stature-intellectual disability syndrome, Retinitis pigmentosa-juvenile cataract-short stature-intellectual disability syndrome |
| RS606231424 |
RDH11
|
Health Risk |
Pathogenic |
Retinitis pigmentosa-juvenile cataract-short stature-intellectual disability syndrome, Retinitis pigmentosa-juvenile cataract-short stature-intellectual disability syndrome |
| RS606231425 |
MMACHC
|
Health Risk |
Pathogenic |
Cobalamin C disease, Cobalamin C disease |
| RS606231426 |
UQCC3
|
Health Risk |
Pathogenic |
Mitochondrial complex III deficiency nuclear type 9, Mitochondrial complex III deficiency nuclear type 9 |
| RS606231430 |
ATP1A3
|
Health Risk |
Likely pathogenic |
Alternating hemiplegia of childhood, Alternating hemiplegia of childhood |
| RS606231432 |
ATP1A3
|
Health Risk |
Pathogenic |
Dystonia 12, Dystonia 12 |
| RS606231434 |
ATP1A3
|
Health Risk |
Pathogenic |
Dystonia 12, Dystonia 12 |
| RS606231435 |
ATP1A3
|
Health Risk |
Pathogenic |
Dystonia 12, Alternating hemiplegia of childhood 2 |
| RS606231436 |
ATP1A3
|
Health Risk |
Likely pathogenic |
— |
| RS606231437 |
ATP1A3
|
Health Risk |
Pathogenic |
Alternating hemiplegia of childhood 2, Dystonia 12 |
| RS606231439 |
ATP1A3
|
Health Risk |
Likely pathogenic |
Dystonia 12, Developmental and epileptic encephalopathy 99 |
| RS606231440 |
ATP1A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Dystonia 12, Dystonia 12 |
| RS606231441 |
ATP1A3
|
Health Risk |
Pathogenic |
Alternating hemiplegia of childhood 2, Dystonia 12 |
| RS606231442 |
ATP1A3
|
Health Risk |
Pathogenic |
Dystonia 12, Dystonia 12 |
| RS606231443 |
ATP1A3
|
Health Risk |
Pathogenic/Likely pathogenic |
Dystonia 12, Developmental and epileptic encephalopathy 99 |
| RS606231444 |
ATP1A3
|
Health Risk |
Likely pathogenic |
Alternating hemiplegia of childhood 2, Cerebellar ataxia-areflexia-pes cavus-optic atrophy-sensorineural hearing loss syndrome |
| RS606231447 |
ATP1A3
|
Health Risk |
Conflicting classifications of pathogenicity |
Dystonia 12, Dystonia 12 |
| RS606231450 |
BRF1
|
Health Risk |
Likely pathogenic |
Cerebellar-facial-dental syndrome, See cases |
| RS606231451 |
TMEM240
|
Health Risk |
Pathogenic/Likely pathogenic |
Spinocerebellar ataxia type 21, Spinocerebellar ataxia type 21 |
| RS606231452 |
TMEM240
|
Health Risk |
Pathogenic |
Spinocerebellar ataxia type 21, Spinocerebellar ataxia type 21 |
| RS606231454 |
TMEM240
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 21, Spinocerebellar ataxia type 21 |
| RS606231455 |
TMEM240
|
Health Risk |
Conflicting classifications of pathogenicity |
Spinocerebellar ataxia type 21, Neurodevelopmental disorder |
| RS606231456 |
NDST1
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal recessive 46 |
| RS606231457 |
NDST1
|
Health Risk |
Pathogenic |
Intellectual disability, autosomal recessive 46 |
| RS606231458 |
NDST1
|
Health Risk |
Likely pathogenic |
Intellectual disability, autosomal recessive 46 |
| RS606231459 |
NDST1
|
Health Risk |
Pathogenic/Likely pathogenic |
Intellectual disability, autosomal recessive 46 |
| RS606231460 |
NLRC4
|
Health Risk |
Pathogenic |
Familial cold autoinflammatory syndrome 4, Periodic fever-infantile enterocolitis-autoinflammatory syndrome |
| RS606231461 |
DMXL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Polyendocrine-polyneuropathy syndrome, See cases |
| RS606231462 |
WDR72
|
Health Risk |
Pathogenic |
Amelogenesis imperfecta hypomaturation type 2A3, Amelogenesis imperfecta hypomaturation type 2A3 |
| RS606231464 |
COL4A1
|
Health Risk |
Pathogenic |
Brain small vessel disease 1 with or without ocular anomalies, Brain small vessel disease 1 with or without ocular anomalies |
| RS606231465 |
COL4A1
|
Health Risk |
Pathogenic |
Brain small vessel disease 1 with or without ocular anomalies, Brain small vessel disease 1 with or without ocular anomalies |
| RS606231466 |
NTRK1
|
Health Risk |
Pathogenic |
Hereditary insensitivity to pain with anhidrosis, Hereditary insensitivity to pain with anhidrosis |
| RS606231467 |
NTRK1
|
Health Risk |
Likely pathogenic |
Hereditary insensitivity to pain with anhidrosis, Hereditary insensitivity to pain with anhidrosis |
| RS606231468 |
GABRB2
|
Health Risk |
Pathogenic |
Developmental and epileptic encephalopathy 92, Developmental and epileptic encephalopathy 92 |
| RS606231469 |
TNNI3K
|
Health Risk |
Likely pathogenic |
Atrial conduction disease, Atrial conduction disease |
| RS606231470 |
COL9A3
|
Health Risk |
Pathogenic |
Stickler syndrome, type 6 |
| RS606231471 |
ECEL1
|
Health Risk |
Pathogenic |
Distal arthrogryposis type 5D, Distal arthrogryposis type 5D |
| RS606231472 |
RMND1
|
Health Risk |
Likely pathogenic |
Combined oxidative phosphorylation defect type 11, Combined oxidative phosphorylation defect type 11 |
| RS606231473 |
CSF3R
|
Health Risk |
Pathogenic/Likely pathogenic |
Severe congenital neutropenia, Autosomal recessive severe congenital neutropenia due to CSF3R deficiency |
| RS606231474 |
CSF3R
|
Health Risk |
Pathogenic |
Autosomal recessive severe congenital neutropenia due to CSF3R deficiency, Autosomal recessive severe congenital neutropenia due to CSF3R deficiency |
| RS606231475 |
CSF3R
|
Health Risk |
Pathogenic |
Autosomal recessive severe congenital neutropenia due to CSF3R deficiency, Autosomal recessive severe congenital neutropenia due to CSF3R deficiency |
| RS60627726 |
KRT6B
|
Health Risk |
Pathogenic |
Pachyonychia congenita 4, Pachyonychia congenita 4 |
| RS6063 |
FGG
|
Health Risk |
Conflicting classifications of pathogenicity |
Fibrinogen Milano XII, digenic |
| RS60637558 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Monogenic diabetes, Permanent neonatal diabetes mellitus |
| RS60652225 |
LMNA
|
Health Risk |
Pathogenic |
Hutchinson-Gilford progeria syndrome, childhood-onset |
| RS60662302 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Insulin-resistant diabetes mellitus AND acanthosis nigricans, Cardiovascular phenotype |
| RS60664170 |
VPS13B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cohen syndrome, Cohen syndrome |
| RS60682848 |
LMNA
|
Health Risk |
Pathogenic |
Dilated cardiomyopathy 1A, Emery-Dreifuss muscular dystrophy 2 |
| RS60687604 |
KRT86
|
Health Risk |
Pathogenic |
Monilethrix, Monilethrix-1 |
| RS6068812 |
CYP24A1
|
Health Risk |
Pathogenic/Likely pathogenic |
Hypercalcemia, infantile |
| RS60695352 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Charcot-Marie-Tooth disease type 2 |
| RS60715293 |
KRT5
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex 1A, generalized severe |
| RS60720877 |
KRT5
|
Health Risk |
Likely pathogenic |
KRT5-related disorder, KRT5-related disorder |
| RS60723330 |
KRT16
|
Health Risk |
Pathogenic |
Palmoplantar keratoderma, nonepidermolytic |
| RS60725382 |
KRT14
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex 1D, generalized |
| RS60734921 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Epilepsy, idiopathic generalized |
| RS60743141 |
TRDN
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Catecholaminergic polymorphic ventricular tachycardia 5 |
| RS60791294 |
ABCC6
|
Health Risk |
Pathogenic |
Autosomal recessive inherited pseudoxanthoma elasticum, Arterial calcification |
| RS60794673 |
PMS2
|
Health Risk |
Conflicting classifications of pathogenicity |
Breast and/or ovarian cancer, Hereditary cancer-predisposing syndrome |
| RS60794845 |
DES
|
Health Risk |
Likely pathogenic |
— |
| RS607969 |
MEN1
|
Health Risk |
Conflicting classifications of pathogenicity |
Multiple endocrine neoplasia, type 1 |
| RS60798368 |
DES
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy, Desmin-related myofibrillar myopathy |
| RS60809236 |
EVC2
|
Health Risk |
Pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS60824529 |
ABCC8
|
Health Risk |
Conflicting classifications of pathogenicity |
Diabetes mellitus, transient neonatal |
| RS60835976 |
RASA1
|
Health Risk |
Likely pathogenic |
Cardiovascular phenotype, Basal cell carcinoma |
| RS60864230 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Familial partial lipodystrophy, Dunnigan type |
| RS6087 |
MPL
|
Health Risk |
Conflicting classifications of pathogenicity |
Congenital amegakaryocytic thrombocytopenia, Thrombocythemia 2 |
| RS60872029 |
LMNA
|
Health Risk |
Pathogenic |
Congenital muscular dystrophy due to LMNA mutation, Charcot-Marie-Tooth disease type 2 |
| RS60890628 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1A, Mandibuloacral dysplasia with type A lipodystrophy |
| RS60891833 |
MECR
|
Health Risk |
Conflicting classifications of pathogenicity |
MECR-related disorder, Inborn genetic diseases |
| RS6089898 |
CHRNA4
|
Health Risk |
Conflicting classifications of pathogenicity |
Autosomal dominant nocturnal frontal lobe epilepsy, Inborn genetic diseases |
| RS6089914 |
KCNQ2
|
Health Risk |
Pathogenic |
Early-infantile DEE, Early-infantile DEE |
| RS60910145 |
APOL1
|
Health Risk |
Conflicting classifications of pathogenicity; risk factor |
Hyalinosis, Segmental Glomerular |
| RS60934003 |
LMNA
|
Health Risk |
Pathogenic |
Emery-Dreifuss muscular dystrophy 2, autosomal dominant |
| RS6094438 |
SLC2A10
|
Health Risk |
Conflicting classifications of pathogenicity |
Arterial tortuosity syndrome, Familial thoracic aortic aneurysm and aortic dissection |
| RS60944949 |
KRT16
|
Health Risk |
Pathogenic |
Pachyonychia congenita 1, Pachyonychia congenita 1 |
| RS60975032 |
ABCC6
|
Health Risk |
Likely pathogenic |
Autosomal recessive inherited pseudoxanthoma elasticum, Autosomal recessive inherited pseudoxanthoma elasticum |
| RS60986317 |
ATP7B
|
Health Risk |
Conflicting classifications of pathogenicity |
Wilson disease, Wilson disease |
| RS60992550 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Charcot-Marie-Tooth disease type 2, Primary dilated cardiomyopathy |
| RS61018135 |
CACNA1H
|
Health Risk |
Conflicting classifications of pathogenicity |
Hyperaldosteronism, familial |
| RS61027685 |
KRT14
|
Health Risk |
Pathogenic |
Epidermolysis bullosa simplex, Epidermolysis bullosa simplex |
| RS61046466 |
LMNA
|
Health Risk |
Pathogenic |
Emery-Dreifuss muscular dystrophy 2, autosomal dominant |
| RS61060395 |
GFAP
|
Health Risk |
Pathogenic |
Alexander disease, Alexander disease |
| RS61064130 |
LMNA
|
Health Risk |
Pathogenic |
Hutchinson-Gilford syndrome, Hutchinson-Gilford syndrome |
| RS61065977 |
SCN4B
|
Health Risk |
Conflicting classifications of pathogenicity |
Cardiovascular phenotype, Long QT syndrome 10 |
| RS61091894 |
KRT86
|
Health Risk |
Pathogenic |
Monilethrix, Monilethrix |
| RS61091998 |
GLI3
|
Health Risk |
Conflicting classifications of pathogenicity |
Polydactyly, Greig cephalopolysyndactyly syndrome |
| RS61094188 |
LMNA
|
Health Risk |
Conflicting classifications of pathogenicity |
Catecholaminergic polymorphic ventricular tachycardia 1, Emery-Dreifuss muscular dystrophy |
| RS61100157 |
P3H1
|
Health Risk |
Conflicting classifications of pathogenicity |
Osteogenesis imperfecta type 8, Osteogenesis Imperfecta |