| RS121908331 |
DMGDH
|
Health Risk |
Likely pathogenic |
Dimethylglycine dehydrogenase deficiency, Dimethylglycine dehydrogenase deficiency |
| RS121908332 |
KCNK9
|
Health Risk |
Pathogenic |
Birk-Barel syndrome, Birk-Barel syndrome |
| RS121908333 |
LDB3
|
Health Risk |
Pathogenic/Likely pathogenic |
Myofibrillar myopathy 4, Cardiomyopathy |
| RS121908334 |
LDB3
|
Health Risk |
Pathogenic/Likely pathogenic |
Myofibrillar myopathy 4, Neuromuscular disease |
| RS121908335 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Myofibrillar myopathy 4, Dilated cardiomyopathy 1C |
| RS121908338 |
LDB3
|
Health Risk |
Conflicting classifications of pathogenicity |
Dilated cardiomyopathy 1C, Primary dilated cardiomyopathy |
| RS121908340 |
ALG1
|
Health Risk |
Pathogenic |
ALG1-congenital disorder of glycosylation, Congenital disorder of glycosylation |
| RS121908341 |
MLC1
|
Health Risk |
Likely pathogenic |
Megalencephalic leukoencephalopathy with subcortical cysts 1, Megalencephalic leukoencephalopathy with subcortical cysts 1 |
| RS121908343 |
MLC1
|
Health Risk |
Pathogenic |
Megalencephalic leukoencephalopathy with subcortical cysts 1, Megalencephalic leukoencephalopathy with subcortical cysts 1 |
| RS121908344 |
MLC1
|
Health Risk |
Pathogenic |
Megalencephalic leukoencephalopathy with subcortical cysts 1, Megalencephalic leukoencephalopathy with subcortical cysts 1 |
| RS121908345 |
MLC1
|
Health Risk |
Pathogenic/Likely pathogenic |
Megalencephalic leukoencephalopathy with subcortical cysts 1, Megalencephalic leukoencephalopathy with subcortical cysts |
| RS121908347 |
CDH23
|
Health Risk |
Pathogenic |
Usher syndrome type 1D, Usher syndrome type 1 |
| RS121908348 |
CDH23
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 12, Hearing loss |
| RS121908349 |
CDH23
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 12, Hearing loss |
| RS121908350 |
CDH23
|
Health Risk |
Pathogenic |
Usher syndrome type 1D, Hearing loss |
| RS121908351 |
CDH23
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 12, Usher syndrome type 1 |
| RS121908352 |
CDH23
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 12, Usher syndrome |
| RS121908354 |
CDH23
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 12, Usher syndrome type 1D |
| RS121908356 |
AIP
|
Health Risk |
Pathogenic |
Pituitary adenoma predisposition, Somatotroph adenoma |
| RS121908357 |
AIP
|
Health Risk |
Pathogenic |
Somatotroph adenoma, Somatotroph adenoma |
| RS121908358 |
FOXL2
|
Health Risk |
Pathogenic |
BLEPHAROPHIMOSIS, PTOSIS |
| RS121908359 |
FOXL2
|
Health Risk |
Conflicting classifications of pathogenicity |
Premature ovarian failure 3, Blepharophimosis |
| RS121908360 |
SLC26A4
|
Health Risk |
Pathogenic |
Pendred syndrome, Pendred syndrome |
| RS121908361 |
SLC26A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 4, Pendred syndrome |
| RS121908362 |
SLC26A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Pendred syndrome, Autosomal recessive nonsyndromic hearing loss 4 |
| RS121908363 |
SLC26A4
|
Health Risk |
Likely pathogenic |
Autosomal recessive nonsyndromic hearing loss 4, Pendred syndrome |
| RS121908364 |
SLC26A4
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 4, Pendred syndrome |
| RS121908365 |
SLC26A4
|
Health Risk |
Pathogenic/Likely pathogenic |
Pendred syndrome, Autosomal recessive nonsyndromic hearing loss 4 |
| RS121908366 |
SLC26A4
|
Health Risk |
Pathogenic |
Autosomal recessive nonsyndromic hearing loss 4, Pendred syndrome |
| RS121908367 |
ATP6V0A4
|
Health Risk |
Pathogenic |
Autosomal recessive distal renal tubular acidosis, Renal tubular acidosis |
| RS121908368 |
ATP6V0A4
|
Health Risk |
Conflicting classifications of pathogenicity |
Renal tubular acidosis, distal |
| RS121908369 |
ATP6V0A4
|
Health Risk |
Pathogenic |
Renal tubular acidosis, distal |
| RS121908370 |
USH1C
|
Health Risk |
Pathogenic |
Usher syndrome type 1C, Autosomal recessive nonsyndromic hearing loss 18A |
| RS121908371 |
MCOLN1
|
Health Risk |
Pathogenic |
Mucolipidosis type IV, Inborn genetic diseases |
| RS121908372 |
MCOLN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucolipidosis type IV, MCOLN1-related disorder |
| RS121908373 |
MCOLN1
|
Health Risk |
Pathogenic |
Mucolipidosis type IV, Mucolipidosis type IV |
| RS121908374 |
MCOLN1
|
Health Risk |
Pathogenic/Likely pathogenic |
Mucolipidosis type IV, Mucolipidosis type IV |
| RS121908375 |
OPA1
|
Health Risk |
Pathogenic/Likely pathogenic |
Autosomal dominant optic atrophy classic form, Optic atrophy with or without deafness |
| RS121908376 |
OPA1
|
Health Risk |
Pathogenic |
Optic atrophy with or without deafness, ophthalmoplegia |
| RS121908377 |
FOXP2
|
Health Risk |
Pathogenic/Likely pathogenic |
Childhood apraxia of speech, FOXP2-related disorder |
| RS121908378 |
FOXP2
|
Health Risk |
Pathogenic |
Childhood apraxia of speech, Inborn genetic diseases |
| RS121908379 |
TNFRSF13B
|
Health Risk |
Pathogenic |
Immunodeficiency, common variable |
| RS121908380 |
MUTYH
|
Health Risk |
Pathogenic |
Familial adenomatous polyposis 2, Hereditary cancer-predisposing syndrome |
| RS121908381 |
MUTYH
|
Health Risk |
Pathogenic |
Familial adenomatous polyposis 2, Hereditary cancer-predisposing syndrome |
| RS121908383 |
MUTYH
|
Health Risk |
Pathogenic |
Gastric cancer, Gastric cancer |
| RS121908384 |
TBCE
|
Health Risk |
Pathogenic |
Hypoparathyroidism-retardation-dysmorphism syndrome, Hypoparathyroidism-retardation-dysmorphism syndrome |
| RS121908385 |
HPS1
|
Health Risk |
Likely pathogenic |
Hermansky-Pudlak syndrome 1, Hermansky-Pudlak syndrome |
| RS121908386 |
HPS1
|
Health Risk |
Pathogenic |
Hermansky-Pudlak syndrome 1, Hermansky-Pudlak syndrome 1 |
| RS121908387 |
SPINK5
|
Health Risk |
Pathogenic |
Netherton syndrome, Ichthyosis linearis circumflexa |
| RS121908388 |
CYLD
|
Health Risk |
Pathogenic |
Familial cylindromatosis, Brooke-Spiegler syndrome |
| RS121908389 |
CYLD
|
Health Risk |
Pathogenic |
Familial multiple trichoepitheliomata, Brooke-Spiegler syndrome |
| RS121908390 |
CYLD
|
Health Risk |
Pathogenic/Likely pathogenic |
Brooke-Spiegler syndrome, Familial cylindromatosis |
| RS121908391 |
TRIM37
|
Health Risk |
Conflicting classifications of pathogenicity |
Mulibrey nanism syndrome, Mulibrey nanism syndrome |
| RS121908402 |
TREM2
|
Health Risk |
Pathogenic/Likely pathogenic |
Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1, Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2 |
| RS121908403 |
SPINT2
|
Health Risk |
Pathogenic |
Congenital secretory sodium diarrhea 3, Congenital secretory sodium diarrhea 3 |
| RS121908404 |
SPINT2
|
Health Risk |
Pathogenic |
Congenital secretory sodium diarrhea 3, Congenital secretory sodium diarrhea 3 |
| RS121908405 |
ANKH
|
Health Risk |
Pathogenic |
Craniometaphyseal dysplasia, autosomal dominant |
| RS121908406 |
ANKH
|
Health Risk |
Pathogenic/Likely pathogenic |
Craniometaphyseal dysplasia, autosomal dominant |
| RS121908407 |
ANKH
|
Health Risk |
Pathogenic |
Chondrocalcinosis 2, Chondrocalcinosis 2 |
| RS121908408 |
ANKH
|
Health Risk |
Pathogenic |
CHONDROCALCINOSIS 2, SPORADIC |
| RS121908409 |
ANKH
|
Health Risk |
Likely pathogenic |
Chondrocalcinosis 2, Chondrocalcinosis 2 |
| RS121908410 |
ANKH
|
Health Risk |
Conflicting classifications of pathogenicity |
Chondrocalcinosis 2, ANKH-related disorder |
| RS121908411 |
HCN4
|
Health Risk |
Pathogenic/Likely pathogenic |
Sick sinus syndrome 2, autosomal dominant |
| RS121908415 |
ACTN4
|
Health Risk |
Pathogenic |
Focal segmental glomerulosclerosis 1, Focal segmental glomerulosclerosis 1 |
| RS121908416 |
ACTN4
|
Health Risk |
Pathogenic |
Focal segmental glomerulosclerosis 1, Focal segmental glomerulosclerosis 1 |
| RS121908417 |
ACTN4
|
Health Risk |
Pathogenic |
Focal segmental glomerulosclerosis 1, Focal segmental glomerulosclerosis 1 |
| RS121908419 |
ACAD8
|
Health Risk |
Pathogenic/Likely pathogenic |
Deficiency of isobutyryl-CoA dehydrogenase, Deficiency of isobutyryl-CoA dehydrogenase |
| RS121908420 |
ACAD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of isobutyryl-CoA dehydrogenase, Deficiency of isobutyryl-CoA dehydrogenase |
| RS121908421 |
ACAD8
|
Health Risk |
Pathogenic |
Deficiency of isobutyryl-CoA dehydrogenase, Deficiency of isobutyryl-CoA dehydrogenase |
| RS121908422 |
ACAD8
|
Health Risk |
Conflicting classifications of pathogenicity |
Deficiency of isobutyryl-CoA dehydrogenase, Deficiency of isobutyryl-CoA dehydrogenase |
| RS121908423 |
KL
|
Health Risk |
Conflicting classifications of pathogenicity |
Tumoral calcinosis, hyperphosphatemic |
| RS121908424 |
EVC
|
Health Risk |
Pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS121908425 |
EVC
|
Health Risk |
Pathogenic |
Ellis-van Creveld syndrome, Short-rib thoracic dysplasia 6 with or without polydactyly |
| RS121908426 |
EVC
|
Health Risk |
Pathogenic/Likely pathogenic |
Ellis-van Creveld syndrome, Curry-Hall syndrome |
| RS121908427 |
SLC12A6
|
Health Risk |
Pathogenic |
Agenesis of the corpus callosum with peripheral neuropathy, See cases |
| RS121908428 |
SLC12A6
|
Health Risk |
Pathogenic |
Agenesis of the corpus callosum with peripheral neuropathy, SLC12A6-related disorder |
| RS121908429 |
SLC12A6
|
Health Risk |
Conflicting classifications of pathogenicity |
Agenesis of the corpus callosum with peripheral neuropathy, Charcot-Marie-Tooth disease |
| RS121908430 |
TRPS1
|
Health Risk |
Pathogenic |
Trichorhinophalangeal dysplasia type I, Trichorhinophalangeal dysplasia type I |
| RS121908431 |
TRPS1
|
Health Risk |
Pathogenic |
Trichorhinophalangeal dysplasia type I, Trichorhinophalangeal syndrome |
| RS121908432 |
TRPS1
|
Health Risk |
Pathogenic |
Trichorhinophalangeal dysplasia type I, TRPS1-related disorder |
| RS121908433 |
TRPS1
|
Health Risk |
Pathogenic |
Trichorhinophalangeal syndrome, type III |
| RS121908434 |
TRPS1
|
Health Risk |
Pathogenic |
Trichorhinophalangeal dysplasia type I, Trichorhinophalangeal dysplasia type I |
| RS121908435 |
TRPS1
|
Health Risk |
Likely pathogenic |
Trichorhinophalangeal syndrome, type III |
| RS121908436 |
TRPS1
|
Health Risk |
Pathogenic |
Trichorhinophalangeal syndrome, type III |
| RS121908440 |
GPC6
|
Health Risk |
Pathogenic |
Autosomal recessive omodysplasia, Autosomal recessive omodysplasia |
| RS121908441 |
KCNE3
|
Health Risk |
Conflicting classifications of pathogenicity |
Brugada syndrome 6, Brugada syndrome |
| RS121908443 |
ALG6
|
Health Risk |
Pathogenic |
ALG6-congenital disorder of glycosylation 1C, ALG6-related disorder |
| RS121908444 |
ALG6
|
Health Risk |
Likely pathogenic |
ALG6-congenital disorder of glycosylation 1C, ALG6-congenital disorder of glycosylation 1C |
| RS121908445 |
CNTNAP2
|
Health Risk |
Conflicting classifications of pathogenicity |
Autism, susceptibility to |
| RS121908446 |
WRN
|
Health Risk |
Pathogenic |
Werner syndrome, Werner syndrome |
| RS121908447 |
WRN
|
Health Risk |
Pathogenic |
Werner syndrome, Werner syndrome |
| RS121908448 |
WRN
|
Health Risk |
Pathogenic |
Werner syndrome, Werner syndrome |
| RS121908449 |
RGS9
|
Health Risk |
Pathogenic |
Bradyopsia, Leber congenital amaurosis |
| RS121908450 |
EDAR
|
Health Risk |
Pathogenic/Likely pathogenic |
Ectodermal dysplasia 10B, hypohidrotic/hair/tooth type |
| RS121908452 |
EDAR
|
Health Risk |
Pathogenic |
Ectodermal dysplasia 10a, hypohidrotic/hair/tooth type |
| RS121908453 |
EDAR
|
Health Risk |
Pathogenic/Likely pathogenic |
Ectodermal dysplasia 10a, hypohidrotic/hair/tooth type |
| RS121908454 |
EDAR
|
Health Risk |
Likely pathogenic |
Ectodermal dysplasia 10B, hypohidrotic/hair/tooth type |
| RS121908455 |
EDAR
|
Health Risk |
Pathogenic |
Ectodermal dysplasia 10B, hypohidrotic/hair/tooth type |
| RS121908456 |
EDAR
|
Health Risk |
Pathogenic |
Ectodermal dysplasia 10a, hypohidrotic/hair/tooth type |
| RS121908457 |
MYOT
|
Health Risk |
Pathogenic/Likely pathogenic |
Progressive distal muscle weakness, Progressive proximal muscle weakness |