RS138213197 HOXB13
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What This Variant Does
"rs138213197, also known as c.251G>
Associated Conditions
Prostate cancer susceptibility
Hereditary cancer-predisposing syndrome
Prostate cancer
hereditary
9
Carcinoma of pancreas
Familial prostate cancer
HOXB13-Related Cancer Predisposition
Breast and/or ovarian cancer
HOXB13-related disorder
Prostate cancer susceptibility
Hereditary cancer-predisposing syndrome
Prostate cancer
hereditary
9
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Prostate cancer | T | OR: 4.32 | 8E-166 | PubMed |
| Prostate cancer | T | OR: 4.32 | 2E-165 | PubMed |
| Cancer of prostate (PheCode 185) | C | OR: 1.41 | 1E-124 | PubMed |
| Cancer of prostate (PheCode 185) | C | OR: 1.38 | 5E-102 | PubMed |
| Prostate cancer | C | OR: 1.43 | 1E-84 | PubMed |
| Prostate cancer | C | OR: 1.43 | 1E-81 | PubMed |
| Prostate cancer | T | OR: 2.61 | 4E-76 | PubMed |
| Prostate cancer | T | OR: 3.85 | 9E-63 | PubMed |
| Prostate cancer | T | OR: 3.98 | 1E-62 | PubMed |
| Prostate cancer | T | OR: 4.46 | 3E-43 | PubMed |
| Prostate cancer | — | OR: 5.01 | 6E-40 | PubMed |
| Prostate cancer | T | OR: 1.53 | 1E-38 | PubMed |
| Prostate cancer | T | OR: 4.48 | 2E-36 | PubMed |
| Elevated prostate specific antigen [PSA] (PheCode 796) | C | OR: 0.75 | 3E-35 | PubMed |
| ICD10 C61: Malignant neoplasm of prostate | T | OR: 2.76 | 2E-29 | PubMed |
| Elevated prostate specific antigen [PSA] (PheCode 796) | C | OR: 0.72 | 3E-26 | PubMed |
| Cancer code, self-reported: prostate cancer (UKB data field 20001_1044) | T | OR: 4 | 6E-23 | PubMed |
| Cancer of prostate (PheCode 185) | T | OR: 2.5 | 3E-19 | PubMed |
| Biological Father: Cancer, Prostate | C | OR: 0.73 | 5E-19 | PubMed |
| Takes medication for prostate cancer? | C | OR: 1.07 | 9E-19 | PubMed |
Other Variants in HOXB13