Familial Prostate Cancer

Cancer 149 variants 28 genes

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Associated Genes (28)

LOC105375751 PRNCR1 - CASC19 CASC21 CASC8 CASC21;CASC8 PTEN BRCA2 CHEK2 TP53 ATM NDUFAF6 FCSK STAT5B FOXP1 KCNQ1 HGD VHL REEP1 SEC61A1 XPC KDM6A MMAB FAH AR XRCC2 PLA2G6

Associated Variants (149)

RSID	Gene	Risk Allele	Odds Ratio	Evidence
RS182352457	LOC105375751	—	—	exploratory
RS183373024	PRNCR1	—	—	exploratory
RS188140481	-	—	—	exploratory
RS1428102803	CASC19	—	—	exploratory
RS138042437	CASC19	—	—	exploratory
RS201885483	CASC21	—	—	exploratory
RS78311688	CASC8	—	—	exploratory
RS201361304	CASC21;CASC8	—	—	exploratory
RS1564568719	PTEN	—	—	strong
RS747073940	BRCA2	—	—	strong
RS1555915295	CHEK2	—	—	strong
RS868137297	TP53	—	—	strong
RS1310128359	BRCA2	—	—	strong
RS1555116381	ATM	—	—	strong
RS765080766	CHEK2	—	—	strong
RS1555281997	BRCA2	—	—	strong
RS1554897856	PTEN	—	—	strong
RS753873681	NDUFAF6	—	—	strong
RS562205568	FCSK	—	—	strong
RS750399917	STAT5B	—	—	strong
RS2146007633	CHEK2	—	—	strong
RS745448468	FOXP1	—	—	strong
RS1273383569	PTEN	—	—	strong
RS2133650175	KCNQ1	—	—	strong
RS2137530514	BRCA2	—	—	strong
RS1057516307	HGD	—	—	strong
RS864622149	CHEK2	—	—	strong
RS5030816	VHL	—	—	strong
RS763395924	CHEK2	—	—	strong
RS876660674	ATM	—	—	strong
RS756250205	CHEK2	—	—	strong
RS200917541	CHEK2	—	—	strong
RS144874997	REEP1	—	—	strong
RS879254212	TP53	—	—	strong
RS879255648	SEC61A1	—	—	strong
RS886039629	CHEK2	—	—	strong
RS1450238352	XPC	—	—	strong
RS886041946	KDM6A	—	—	strong
RS756195708	MMAB	—	—	strong
RS1057523975	PTEN	—	—	strong
RS767329352	FAH	—	—	strong
RS200185441	AR	—	—	strong
RS1060500116	PTEN	—	—	strong
RS1060502477	BRCA2	—	—	strong
RS560785131	XRCC2	—	—	strong
RS767043399	CHEK2	—	—	strong
RS1114167621	PTEN	—	—	strong
RS1131691148	ATM	—	—	strong
RS750939090	PLA2G6	—	—	strong
RS1555525857	TP53	—	—	strong

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