RS4646450 CYP3A5
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Associated Conditions
appendicular lean mass relative to body height
appendicular lean mass relative to body height
GWAS Studies (12)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Blood metabolite levels | — | — | 5E-50 | PubMed |
| Triglycerides to Total Lipids in Very Large VLDL percentage | A | β: 0.02 | 8E-14 | PubMed |
| Testosterone levels | A | β: 0.026 | 9E-14 | PubMed |
| Cholesteryl Esters to Total Lipids in Large VLDL percentage | A | β: 0.02 | 3E-13 | PubMed |
| Testosterone levels | A | β: 0.025 | 8E-13 | PubMed |
| Cholesterol to Total Lipids in Very Large VLDL percentage | A | β: 0.02 | 1E-12 | PubMed |
| Free Cholesterol to Total Lipids in Large HDL percentage | A | β: 0.02 | 2E-12 | PubMed |
| Cholesterol to Total Lipids in Large VLDL percentage | A | β: 0.02 | 1E-11 | PubMed |
| Free Cholesterol to Total Lipids in Very Large VLDL percentage | A | β: 0.02 | 1E-11 | PubMed |
| Neutrophil count | A | β: 0.016 | 5E-10 | PubMed |
| Hypertension (confirmatory factor analysis Factor 12) | — | — | 3E-8 | PubMed |
| 16a-hydroxy DHEA 3-sulfate levels | — | — | 5E-7 | PubMed |
Population Frequencies
1kG AFR
96.5%
1kG ALL
46.7%
1kG AMR
29.7%
1kG EAS
30%
1kG EUR
16.5%
1kG SAS
39.8%
Other Variants in CYP3A5