RS182549 MCM6
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What This Variant Does
"Also known as 'G/A(-22018)' and located in the MCM6 but with influence on the lactase LCT gene, rs18...
Associated Conditions
LACTASE PERSISTENCE
LACTASE PERSISTENCE
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| 1,5-anhydroglucitol levels | C | OR: 16.91 | 4E-64 | PubMed |
| Gut microbiota relative abundance (hMGS.00004: Bifidobacterium adolescentis) | T | — | 2E-45 | PubMed |
| Gut microbial functional pathway relative abundance (KEGG-module M00244: Putative zinc/manganese transport system) | T | OR: 0.13 | 3E-33 | PubMed |
| Gut microbiome order abundance (Actinomycetales) | T | OR: 0.13 | 3E-25 | PubMed |
| Gut microbiome class abundance (Actinomycetia) | T | OR: 0.13 | 4E-25 | PubMed |
| Gut microbiome genus abundance (Bifidobacterium) | T | OR: 0.13 | 8E-25 | PubMed |
| Gut microbiome family abundance (Bifidobacteriaceae) | T | OR: 0.13 | 1E-24 | PubMed |
| Insulin-induced gene 1 protein protein levels (SomaScan ID:9017-58) | T | OR: 1.18 | 3E-23 | PubMed |
| Gut microbial functional pathway relative abundance (KEGG-module M00168: CAM (Crassulacean acid metabolism), dark) | T | β: 0.1 | 2E-22 | PubMed |
| Gut microbiota abundance (genus Bifidobacterium id.436) | C | OR: 9.31 | 1E-20 | PubMed |
| Bifidobacterium adolescentis abundance in stool | C | OR: 0.21 | 3E-20 | PubMed |
| Gut microbiota abundance (class Actinobacteria id.419) | C | OR: 9.19 | 4E-20 | PubMed |
| Gut microbiota abundance (family Bifidobacteriaceae id.433) | C | OR: 9.15 | 6E-20 | PubMed |
| Gut microbiota abundance (order Bifidobacteriales id.432) | C | OR: 9.15 | 6E-20 | PubMed |
| Gut microbiome phylum abundance (Actinomycetota) | T | OR: 0.11 | 6E-20 | PubMed |
| Urine X-12722 levels in chronic kidney disease | T | OR: 0.19 | 5E-17 | PubMed |
| Gut microbiome species abundance (Bifidobacterium adolescentis, GCF_000010425.1) | T | β: 0.1 | 2E-16 | PubMed |
| Gut microbiota abundance (k_Bacteria.p_Actinobacteria.c_Actinobacteria.o_Bifidobacteriales.f_Bifidobacteriaceae) | T | OR: 0.15 | 6E-15 | PubMed |
| Gut microbiota abundance (k_Bacteria.p_Actinobacteria.c_Actinobacteria.o_Bifidobacteriales) | T | OR: 0.15 | 6E-15 | PubMed |
| Gut microbiota abundance (k_Bacteria.p_Actinobacteria.c_Actinobacteria.o_Bifidobacteriales.f_Bifidobacteriaceae.g_Bifidobacterium) | T | OR: 0.15 | 9E-15 | PubMed |
Other Variants in MCM6