IGF2BP2 Chromosome 3
Insulin like growth factor 2 mRNA binding protein 2
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What This Gene Does
This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]
Gene Info
Gene Group
"RNA binding motif containing|MicroRNA protein coding host genes"
Locus Type
gene with protein product
Location
3q27.2
Ensembl
ENSG00000073792
Associated Conditions (2)
Diabetes mellitus type 2
susceptibility to
Key Variants
All Variants (1)
| RSID | Category | Clinical Significance | Conditions |
|---|---|---|---|
| RS4402960 | Health Risk | risk factor | Diabetes mellitus type 2, susceptibility to, Diabetes mellitus type 2 |