Diffuse Pediatric-type High-grade Glioma

Cancer 53 variants 24 genes

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Associated Genes (24)

TP53 NF1 FGFR1 SDHA PIK3CA PTEN PMS2 CDK4 RET MAX PIK3R1 TERT ATM ACVR1 KRAS RB1 PTPN11 NRAS BRAF AKT1 EGFR FBXW7 MSH6 MSH2

Associated Variants (53)

RSID	Gene	Risk Allele	Odds Ratio	Evidence
RS1555525857	TP53	—	—	strong
RS745407845	NF1	—	—	strong
RS779707422	FGFR1	—	—	strong
RS377470390	SDHA	—	—	strong
RS886039484	TP53	—	—	strong
RS121913287	PIK3CA	—	—	strong
RS121913288	PIK3CA	—	—	strong
RS121913277	PIK3CA	—	—	strong
RS867262025	PIK3CA	—	—	strong
RS1057519991	TP53	—	—	strong
RS1060501191	TP53	—	—	strong
RS867114783	TP53	—	—	strong
RS1555534596	NF1	—	—	strong
RS863224447	NF1	—	—	strong
RS1554898129	PTEN	—	—	strong
RS1554292741	PMS2	—	—	strong
RS1446831422	CDK4	—	—	strong
RS1553821144	PIK3CA	—	—	strong
RS373594744	RET	—	—	strong
RS587780068	TP53	—	—	strong
RS2063106020	MAX	—	—	strong
RS1747645807	PIK3R1	—	—	strong
RS1242535815	TERT	—	—	strong
RS1278985870	ATM	—	—	strong
RS1443098123	TP53	—	—	strong
RS121912678	ACVR1	—	—	strong
RS121912651	TP53	—	—	strong
RS28934574	TP53	—	—	strong
RS28934576	TP53	—	—	strong
RS28934874	TP53	—	—	strong
RS121913530	KRAS	—	—	strong
RS121913529	KRAS	—	—	strong
RS587776780	RB1	—	—	strong
RS121918454	PTPN11	—	—	strong
RS121913279	PIK3CA	—	—	strong
RS121434596	NRAS	—	—	strong
RS121913364	BRAF	—	—	strong
RS121434592	AKT1	—	—	strong
RS121909226	PTEN	—	—	strong
RS397514560	PTEN	—	—	strong
RS121913343	TP53	—	—	strong
RS397517126	EGFR	—	—	strong
RS397517201	PIK3CA	—	—	strong
RS149680468	FBXW7	—	—	strong
RS267608078	MSH6	—	—	strong
RS63749915	MSH2	—	—	strong
RS121913344	TP53	—	—	strong
RS17882252	TP53	—	—	strong
RS750600586	TP53	—	—	strong
RS121913293	PTEN	—	—	strong

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