RS28934576 TP53
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What This Variant Does
"rs28934576, also known as Arg273His or R273H, is a SNP in the p53 TP53 tumor suppressor gene. The mi...
Associated Conditions
Li-Fraumeni syndrome 1
Thyroid gland undifferentiated (anaplastic) carcinoma
Hereditary cancer-predisposing syndrome
Squamous cell carcinoma of the head and neck
Li-Fraumeni syndrome
Lung adenocarcinoma
Neoplasm
Ovarian neoplasm
Rhabdomyosarcoma
Malignant tumor of breast
Familial cancer of breast
Multiple myeloma
Colorectal cancer
Adrenocortical carcinoma
hereditary
GWAS Studies (1)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Body fat percentage (adjusted for testosterone and SHBG) | — | OR: 3.86 | 1E-8 | PubMed |
Other Variants in TP53