RS972283 Unknown gene
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What This Variant Does
"Genetic risk profiling for prediction of type 2 diabetes. [GWAS:Type 2 diabetes]"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Metabolic biomarkers (multivariate analysis) | A | — | 9E-98 | PubMed |
| Triglycerides | A | β: 0.033 | 2E-62 | PubMed |
| High density lipoprotein cholesterol levels | A | β: 0.03 | 2E-60 | PubMed |
| Body fat percentage | A | β: 0.014 | 2E-22 | PubMed |
| Body fat percentage (UKB data field 23099) | G | β: 0.013 | 5E-20 | PubMed |
| circulating leptin levels adjusted for BMI | G | β: 0.056 | 4E-18 | PubMed |
| circulating leptin levels adjusted for BMI | G | β: 0.053 | 6E-18 | PubMed |
| Medication use (agents acting on the renin-angiotensin system) | G | β: 0.044 | 8E-18 | PubMed |
| circulating leptin levels adjusted for BMI | G | β: 0.079 | 8E-18 | PubMed |
| Diastolic blood pressure | A | OR: 0.11 | 3E-16 | PubMed |
| Hypertension | A | OR: 8 | 1E-15 | PubMed |
| circulating leptin levels adjusted for BMI | G | β: 0.063 | 4E-15 | PubMed |
| Leg fat percentage right (UKB data field 23111) | G | β: 0.009 | 4E-15 | PubMed |
| Systolic blood pressure | A | OR: 0.17 | 5E-15 | PubMed |
| circulating leptin levels adjusted for BMI | G | β: 0.066 | 1E-14 | PubMed |
| Diastolic blood pressure | A | OR: 0.12 | 4E-14 | PubMed |
| circulating leptin levels adjusted for BMI | G | β: 0.071 | 6E-14 | PubMed |
| Arm fat percentage right (UKB data field 23119) | G | β: 0.011 | 8E-14 | PubMed |
| Leg fat percentage left (UKB data field 23115) | G | β: 0.009 | 1E-13 | PubMed |
| Trunk fat mass (UKB data field 23128) | G | β: 0.014 | 2E-13 | PubMed |