Genetic variant

rs934197

rs934197 is a single-letter difference in human DNA, on chromosome 2. Carrying it does not, on its own, mean you have or will develop any condition.

Register free Do I have this variant?

What is this?

Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs934197 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.

Multiple genetic determinants of plasma lipid levels in Caribbean Hispanics. beta-Carotene conversio...

From SNPedia

Why might it matter?

ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.

Do I have this variant?

If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs934197, if your test read this position.

Register free Upload DNA Log in

Connect this with your blood results

A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.

Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.

Upload blood results

What should I do next?

  1. Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
  2. Put it in context. Add your blood results, so the variant can be read against what your body is doing.
  3. Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
  4. Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
Register free Upload DNA Upload blood results Ask Dr. Hemsworth

This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.

Technical details

dbSNP ID
rs934197
Position
chr2:21044589

Genome-wide association studies (20)

TraitRisk alleleOR / betaP-valueStudy
Low density lipoprotein cholesterol levels — — 9E-971 PubMed
Total cholesterol levels — — 5E-796 PubMed
Low density lipoprotein cholesterol levels A β 0.096 2E-693 PubMed
Non-HDL cholesterol levels — — 2E-670 PubMed
Total cholesterol levels A β 0.085 4E-544 PubMed
Non-HDL cholesterol levels A β 0.094 2E-472 PubMed
LDL cholesterol levels G β 0.083 9E-312 PubMed
Cholesteryl esters to total lipids ratio in small LDL A β 0.099 4E-116 PubMed
Cholesteryl esters to total lipids ratio in medium LDL A β 0.098 5E-115 PubMed
Cholesteryl esters to total lipids ratio in large LDL A β 0.098 6E-115 PubMed
Remnant cholesterol (non-HDL, non-LDL -cholesterol) A β 0.097 4E-112 PubMed
Total cholesterol to total lipids ratio in small LDL A β 0.09 4E-98 PubMed
Total cholesterol to total lipids ratio in medium LDL A β 0.086 3E-89 PubMed
Total cholesterol to total lipids ratio in large LDL A β 0.086 5E-89 PubMed
LDL cholesterol levels x long total sleep time interaction (2df test) — OR 3.4 3E-78 PubMed
Triglycerides to total lipids ratio in large VLDL G β 0.074 1E-64 PubMed
Phospholipids to total lipids ratio in very large VLDL G β 0.072 2E-60 PubMed
Cholesteryl esters to total lipids ratio in small VLDL G β 0.064 1E-49 PubMed
Cholesterol to total lipids ratio in large VLDL G β 0.062 2E-47 PubMed
Low density lipoprotein cholesterol levels A OR 0.11 2E-45 PubMed

Sources