RS8283 Unknown gene
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What This Variant Does
"High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Serum levels of protein C4A;C4B | G | OR: 0.48 | 4E-102 | PubMed |
| Serum levels of protein FTMT | G | OR: 0.34 | 1E-46 | PubMed |
| MRPS34 protein levels | — | OR: 0.55 | 2E-36 | PubMed |
| TRIM42 protein levels | — | OR: 0.54 | 2E-35 | PubMed |
| TTC24 protein levels | — | OR: 0.54 | 2E-35 | PubMed |
| Serum levels of protein IL21 | G | OR: 0.27 | 1E-29 | PubMed |
| NEURL1B protein levels | — | OR: 0.46 | 5E-25 | PubMed |
| Oligomannose structures (multivariate analysis) | A | β: 0.015 | 3E-21 | PubMed |
| Ubiquitin carboxyl-terminal hydrolase 25 levels | G | OR: 0.25 | 4E-20 | PubMed |
| Percentage of M9 (GP18) | A | OR: 0.2 | 3E-19 | PubMed |
| Complement C4b levels | G | OR: 0.49 | 2E-17 | PubMed |
| FSD1 protein levels | — | OR: 0.35 | 1E-15 | PubMed |
| Rheumatoid arthritis or multiple sclerosis | — | — | 3E-15 | PubMed |
| Saturated fatty acids levels | G | — | 2E-14 | PubMed |
| Monounsaturated fatty acid levels | G | — | 5E-12 | PubMed |
| Monounsaturated fatty acid levels | G | — | 6E-12 | PubMed |
| Serum levels of protein TYK2 | G | OR: 0.16 | 3E-11 | PubMed |
| Omega-6 fatty acids to total fatty acids percentage | G | — | 4E-10 | PubMed |
| Omega-6 fatty acid levels | G | — | 1E-9 | PubMed |
| Total fatty acid levels | G | — | 1E-9 | PubMed |