RS8050136 Unknown gene
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What This Variant Does
"This SNP is in a linkage block in the FTO gene with rs1121980
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Type 2 diabetes or polycystic ovary syndrome (pleiotropy) | A | — | 2E-85 | PubMed |
| Body mass index | A | β: 0.084 | 2E-58 | PubMed |
| Body mass index (joint analysis main effects and physical activity interaction) | — | — | 4E-54 | PubMed |
| Body mass index | A | OR: 8.04 | 1E-47 | PubMed |
| Type 2 diabetes | A | OR: 0.11 | 3E-39 | PubMed |
| Body mass index in physically active individuals | A | β: 0.079 | 4E-39 | PubMed |
| Weight | A | OR: 7.05 | 5E-36 | PubMed |
| Adiposity | C | β: 0.06 | 3E-26 | PubMed |
| Blood urea nitrogen levels | A | β: 0.007 | 3E-23 | PubMed |
| Body fat percentage or coronary artery disease (MTAG) | — | β: 0.027 | 4E-19 | PubMed |
| Body mass index in physically inactive individuals | A | β: 0.093 | 2E-18 | PubMed |
| Type 2 diabetes | — | OR: 1.3 | 2E-17 | PubMed |
| Menarche (age at onset) | C | β: 0.04 | 2E-17 | PubMed |
| Body mass index | — | β: 0.056 | 7E-17 | PubMed |
| Type 2 diabetes | A | OR: 1.23 | 7E-14 | PubMed |
| Type 2 diabetes | A | OR: 1.17 | 1E-12 | PubMed |
| Pulse pressure (BMI unadjusted) | A | OR: 0.64 | 9E-11 | PubMed |
| Urate levels | A | β: 0.025 | 2E-10 | PubMed |
| Obesity (extreme) | A | OR: 1.51 | 8E-10 | PubMed |
| Body mass in chronic obstructive pulmonary disease | A | — | 4E-8 | PubMed |