Genetic variant
rs8034802
rs8034802 is a single-letter difference in human DNA, on chromosome 15. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs8034802 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
Do Genetic Modifiers of HDL-C and Triglyceride Levels also Modify Their Response to a Lifestyle Intervention in the Setting of Obesity and Type-2 Diabetes Mellitus? The Look AHEAD Study
From SNPedia
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs8034802, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs8034802
- Position
- chr15:58432593
Genome-wide association studies (11)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| High density lipoprotein cholesterol levels | — | OR 0.84 | 3E-13 | PubMed |
| Phosphatidylethanolamine(34:2)_[M+H]1+ levels | T | β 0.036 | 5E-10 | PubMed |
| Phosphatidylethanolamine(36:4)_[M-H]1- levels | A | β 0.076 | 5E-10 | PubMed |
| Phosphatidylethanolamine(36:4)_[M+H]1+ levels | C | β 0.078 | 5E-10 | PubMed |
| Phosphatidylcholine(33:3)_[M+H]1+/Phosphatidylethanolamine(36:3)_[M+H]1+/Phosphatidate(38:4)_[M+NH4]1+ levels | G | β 0.069 | 5E-10 | PubMed |
| Phosphatidylcholine(33:2)_[M+H]1+/Phosphatidylethanolamine(36:2)_[M+H]1+/Phosphatidate(38:3)_[M+NH4]1+ levels | T | β 0.064 | 5E-10 | PubMed |
| Phosphatidylethanolamine(38:5)_[M-H]1- levels | G | β 0.077 | 5E-10 | PubMed |
| Phosphatidylcholine(35:4)_[M+H]1+/Phosphatidylethanolamine(38:4)_[M+H]1+/Phosphatidate(40:5)_[M+NH4]1+ levels | C | β 0.036 | 5E-10 | PubMed |
| Phosphatidylcholine(37:6)_[M+H]1+/Phosphatidylethanolamine(40:6)_[M+H]1+/Phosphatidate(42:7)_[M+NH4]1+ levels | A | β 0.063 | 5E-10 | PubMed |
| HDL cholesterol | A | OR 0.1 | 1E-9 | PubMed |
| Phosphatidylcholine (16:0_18:1) levels | A | OR 0.13 | 8E-8 | PubMed |
Sources
- dbSNP: rs8034802 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies