Genetic variant

rs737092

rs737092 is a single-letter difference in human DNA, on chromosome 20. Carrying it does not, on its own, mean you have or will develop any condition.

Register free Do I have this variant?

What is this?

Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs737092 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.

We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.

Why might it matter?

ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.

Do I have this variant?

If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs737092, if your test read this position.

Register free Upload DNA Log in

Connect this with your blood results

A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.

Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.

Upload blood results

What should I do next?

  1. Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
  2. Put it in context. Add your blood results, so the variant can be read against what your body is doing.
  3. Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
  4. Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
Register free Upload DNA Upload blood results Ask Dr. Hemsworth

This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.

Technical details

dbSNP ID
rs737092
Position
chr20:57415349

Genome-wide association studies (20)

TraitRisk alleleOR / betaP-valueStudy
Mean corpuscular hemoglobin C — 5E-300 PubMed
mean corpuscular volume (MCV, mean, inv-norm transformed) T OR 0.1 6E-297 PubMed
mean corpuscular volume (MCV, maximum, inv-norm transformed) T OR 0.1 7E-291 PubMed
Mean corpuscular hemoglobin C β 0.068 1E-272 PubMed
mean corpuscular hemoglobin (MCH, maximum, inv-norm transformed) T β 0.096 1E-250 PubMed
Mean corpuscular volume C β 0.065 3E-236 PubMed
mean corpuscular hemoglobin (MCH, mean, inv-norm transformed) T β 0.095 6E-236 PubMed
Mean corpuscular haemoglobin (UKB data field 30050) C β 0.054 7E-200 PubMed
Mean corpuscular hemoglobin C β 0.055 6E-166 PubMed
mean corpuscular volume (MCV, mean, inv-norm transformed) T β 0.086 1E-151 PubMed
mean corpuscular volume (MCV, maximum, inv-norm transformed) T β 0.083 7E-143 PubMed
mean corpuscular volume (MCV, minimum, inv-norm transformed) T β 0.08 8E-136 PubMed
mean corpuscular hemoglobin (MCH, maximum, inv-norm transformed) T β 0.077 6E-118 PubMed
mean corpuscular hemoglobin (MCH, mean, inv-norm transformed) T β 0.077 1E-116 PubMed
mean corpuscular hemoglobin (MCH, minimum, inv-norm transformed) T β 0.068 2E-100 PubMed
Mean corpuscular volume C β 0.067 2E-68 PubMed
Red blood cell count C — 8E-67 PubMed
Mean corpuscular volume C β 0.056 3E-53 PubMed
Mean corpuscular volume T β 0.062 1E-49 PubMed
Red blood cell count T β 0.016 5E-46 PubMed

Sources