Genetic variant
rs7115739
rs7115739 is a single-letter difference in human DNA, on chromosome 11. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs7115739 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
rs7115739 and rs174570 http://www.sciencemag.org/content/349/6254/1343.full Greenlandic Inuit show g...
From SNPedia
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs7115739, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs7115739
- Position
- chr11:61874245
Genome-wide association studies (20)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| Omega-3 fatty acids to total fatty acids percentage | T | — | 2E-170 | PubMed |
| Omega-3 fatty acids to Omega-6 fatty acids ratio | T | — | 9E-153 | PubMed |
| Omega-3 fatty acids to total fatty acids percentage | T | — | 9E-140 | PubMed |
| Omega-3 fatty acids to total fatty acids percentage | T | — | 9E-138 | PubMed |
| Omega-3 fatty acids to Omega-6 fatty acids ratio | T | — | 6E-136 | PubMed |
| Omega-3 fatty acid levels | T | — | 3E-134 | PubMed |
| Omega-3 fatty acid levels | T | — | 8E-129 | PubMed |
| Degree of unsaturation | T | — | 2E-127 | PubMed |
| Omega-3 fatty acids to Omega-6 fatty acids ratio | T | — | 4E-124 | PubMed |
| Degree of unsaturation | T | — | 8E-112 | PubMed |
| Degree of unsaturation | T | — | 2E-107 | PubMed |
| Omega-3 fatty acid levels | T | — | 3E-105 | PubMed |
| Omega-3 fatty acids to total fatty acids percentage | T | — | 1E-102 | PubMed |
| Docosahexaenoic acid levels | T | — | 9E-97 | PubMed |
| Omega-3 fatty acids to Omega-6 fatty acids ratio | T | — | 3E-89 | PubMed |
| Omega-3 fatty acids to total fatty acids percentage | T | — | 8E-85 | PubMed |
| Omega-3 fatty acids to Omega-6 fatty acids ratio | T | — | 5E-84 | PubMed |
| Omega-3 fatty acids to total fatty acids percentage | T | — | 8E-84 | PubMed |
| Docosahexaenoic acid to total fatty acids percentage | T | — | 9E-83 | PubMed |
| Docosahexaenoic acid levels | T | — | 2E-82 | PubMed |
Sources
- dbSNP: rs7115739 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies