RS689 Unknown gene
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What This Variant Does
"A strong association between rs689, a SNP within the insulin INS gene, has been reported with type-1...
GWAS Studies (13)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Type 1 diabetes | A | — | 5E-196 | PubMed |
| Type 1 diabetes | T | OR: 2.21 | 1E-160 | PubMed |
| Type 1 diabetes | A | OR: 0.56 | 3E-152 | PubMed |
| Type 1 diabetes | T | OR: 2.38 | 1E-100 | PubMed |
| Type 1 diabetes | A | OR: 0.59 | 2E-45 | PubMed |
| Type 1 diabetes | A | OR: 0.62 | 2E-39 | PubMed |
| Age of onset of type 1 diabetes | A | OR: 0.37 | 3E-28 | PubMed |
| Latent autoimmune diabetes vs. type 2 diabetes | — | OR: 1.47 | 1E-18 | PubMed |
| Glucose levels (UKB data field 30740) | T | β: 0.02 | 5E-17 | PubMed |
| Type 1 diabetes | — | OR: 1.03 | 5E-12 | PubMed |
| C-peptide levels in type I diabetes | T | OR: 0.14 | 6E-7 | PubMed |
| Type 1 diabetes | — | OR: 2.44 | 1E-6 | PubMed |
| Type 1 diabetes | A | OR: 0.92 | 8E-6 | PubMed |