Genetic variant
rs6882076
rs6882076 is a single-letter difference in human DNA, on chromosome 5. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs6882076 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs6882076, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs6882076
- Position
- chr5:156963286
Genome-wide association studies (20)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| T-cell immunoglobulin and mucin domain-containing protein 4 levels | T | OR 0.96 | 1E-363 | PubMed |
| Total cholesterol levels | T | β 0.054 | 1E-207 | PubMed |
| Low-density lipoprotein levels | T | β 0.047 | 4E-147 | PubMed |
| Triglyceride levels | T | β 0.044 | 6E-139 | PubMed |
| triglyceride (mean, inv-norm transformed) | T | β 0.07 | 8E-129 | PubMed |
| Non-HDL cholesterol levels | T | β 0.045 | 8E-112 | PubMed |
| Triglyceride levels | C | β 0.034 | 1E-84 | PubMed |
| Low density lipoprotein cholesterol levels | — | β 0.047 | 2E-69 | PubMed |
| Cholesterol levels (UKB data field 30690) | C | β 0.037 | 3E-69 | PubMed |
| Triglyceride levels (UKB data field 30870) | C | β 0.032 | 6E-63 | PubMed |
| Triglycerides | C | β 0.035 | 2E-57 | PubMed |
| Triglyceride levels | T | β 0.033 | 2E-57 | PubMed |
| Phospholipids to Total Lipids in Very Small VLDL percentage | C | β 0.03 | 1E-51 | PubMed |
| Polyunsaturated fatty acid levels | T | — | 2E-49 | PubMed |
| Omega-6 fatty acid levels | T | — | 2E-47 | PubMed |
| Total fatty acid levels | T | — | 3E-45 | PubMed |
| Total fatty acid levels | T | — | 1E-44 | PubMed |
| Total cholesterol levels | T | β 0.051 | 2E-43 | PubMed |
| Monounsaturated fatty acid levels | T | — | 3E-42 | PubMed |
| Monounsaturated fatty acid levels | T | — | 2E-41 | PubMed |
Sources
- dbSNP: rs6882076 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies