Genetic variant
rs6567160
rs6567160 is a single-letter difference in human DNA, on chromosome 18. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs6567160 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs6567160, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs6567160
- Position
- chr18:60161902
Genome-wide association studies (20)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| Weight | T | β 0.055 | 7E-313 | PubMed |
| Body mass index | T | β 0.064 | 2E-269 | PubMed |
| Weight (maximum, inv-normal transformed) | T | OR 0.11 | 1E-234 | PubMed |
| Weight (mean, inv-normal transformed) | T | OR 0.11 | 2E-226 | PubMed |
| Basal metabolic rate (UKB data field 23105) | C | β 0.04 | 6E-188 | PubMed |
| Body mass index | T | β 0.055 | 8E-184 | PubMed |
| Body mass index | T | β 0.055 | 8E-184 | PubMed |
| Body mass index | T | β 0.055 | 8E-184 | PubMed |
| Body mass index (MTAG) | T | β 0.053 | 5E-180 | PubMed |
| Weight (UKB data field 21002) | C | β 0.051 | 1E-157 | PubMed |
| Weight (minimum, inv-normal transformed) | T | β 0.087 | 4E-154 | PubMed |
| Height (maximum, inv-normal transformed) | T | β 0.087 | 3E-153 | PubMed |
| height (mean, inv-normal transformed) | T | β 0.087 | 1E-148 | PubMed |
| Body mass index (BMI, maximum, inv-normal transformed) | T | β 0.091 | 1E-147 | PubMed |
| Whole body fat free mass (UKB data field 23101) | C | β 0.04 | 5E-143 | PubMed |
| Body mass index (BMI, mean, inv-normal transformed) | T | β 0.087 | 2E-137 | PubMed |
| Body mass index | — | — | 7E-126 | PubMed |
| Body mass index | — | — | 1E-125 | PubMed |
| Metabolic syndrome | — | β 0.042 | 4E-124 | PubMed |
| Body mass index | C | β 0.052 | 3E-118 | PubMed |
Sources
- dbSNP: rs6567160 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies