RS6544713 Unknown gene
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What This Variant Does
"}}per the 23andMe blog, the minor allele of this SNP (T) was associated with increased LDL cholester..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Campesterol levels | C | OR: 0.33 | 3E-37 | PubMed |
| Free Cholesterol to Total Lipids in Small VLDL percentage | C | β: 0.02 | 1E-25 | PubMed |
| Sterol ester (27:1/20:2) levels | T | OR: 0.29 | 2E-24 | PubMed |
| LDL cholesterol levels | T | OR: 1.93 | 3E-24 | PubMed |
| Ratio of apolipoprotein B to apolipoprotein A1 levels | T | β: 0.043 | 6E-23 | PubMed |
| Phospholipids to total lipids ratio in large HDL | T | β: 0.041 | 1E-21 | PubMed |
| Mixed hyperlipidemia (PheCode 272.13) | T | β: 0.05 | 2E-21 | PubMed |
| Phospholipids to total lipids ratio in medium VLDL | T | β: 0.04 | 2E-21 | PubMed |
| LDL cholesterol | T | OR: 0.15 | 2E-20 | PubMed |
| Cholesteryl esters to total lipids ratio in small VLDL | T | β: 0.041 | 6E-20 | PubMed |
| Coronary artery disease | — | — | 1E-19 | PubMed |
| Coronary artery disease | T | β: 0.055 | 6E-19 | PubMed |
| Total cholesterol to total lipids ratio in medium VLDL | T | β: 0.04 | 1E-18 | PubMed |
| Coronary artery disease | T | β: 0.049 | 2E-18 | PubMed |
| Cholesterol to Total Lipids in Small LDL percentage | C | β: 0.02 | 3E-18 | PubMed |
| Cholesteryl esters to total lipids ratio in medium VLDL | T | β: 0.037 | 2E-16 | PubMed |
| Triglycerides to total lipids ratio in large VLDL | T | β: 0.037 | 6E-16 | PubMed |
| Coronary artery disease or fibrinogen levels (pleiotropy) | — | — | 6E-15 | PubMed |
| Coronary artery disease or tissue plasminogen activator levels (pleiotropy) | — | — | 8E-15 | PubMed |
| Coronary artery disease or von Willebrand factor levels (pleiotropy) | — | — | 8E-15 | PubMed |